Results 261 to 270 of about 602,933 (343)

Timing of Peri‐Ictal MRI Abnormalities in Status Epilepticus – One Size Does Not Fit All

Annals of Neurology, EarlyView.
Objective We aimed to investigate timing of occurrence of peri‐ictal MRI abnormalities – a potential risk biomarker of status epilepticus‐related cerebral injury (t2). Methods This prospective study enrolled adult patients with status epilepticus and acute magnetic resonance imaging (MRI); patients with peri‐ictal MRI abnormalities underwent follow‐up ...
Pilar Bosque Varela, Lukas Machegger, Tanja Prüwasser, Wanda Lauth, Jürgen Steinbacher, Andreas Oellerer, Georg Zimmermann, Johannes Pfaff, Mark McCoy, Bernardo Crespo Pimentel, Markus Leitinger, Eugen Trinka, Giorgi Kuchukhidze   +12 more
wiley   +1 more source

Trelagliptin Ameliorates Memory Decline in Diabetic Rats through the AMPK/AKT/GSK-3β Pathway in the Cerebral Cortex. [PDF]

ACS Omega
Yao Y, Shu T, Guo X, Huang J, Chen Q, Liu X, Ouyang C, Yang X, Lei M.   +8 more
europepmc   +1 more source

Harnessing the Neurobiology of Empathy and Compassion to Alleviate Burnout in Neurology

Annals of Neurology, EarlyView.
The neurologist cares for patients with complex chronic conditions that compromise their wellbeing. Many such disorders are poorly understood. Whereas for some, effective symptomatic treatments exist, for most we lack an understanding of the molecular and cellular bases for disease pathogenesis needed for discovering disease‐modifying treatments ...
Fadel Zeidan, Joseph D. Stern, William C. Mobley   +2 more
wiley   +1 more source

Anatomical Progression of Neuropathology in FTLD‐TDP Type C and Linkage to Annexin A11

Annals of Neurology, EarlyView.
Objective Frontotemporal lobar degenerations (FTLD)‐TDP type C (TDP‐C) is distinguished from other FTLD‐TDP subtypes by 3 unique features: (1) invariable onset in the anterior temporal lobe (ATL), (2) phosphorylated TDP‐43 (pTDP) neurites in cortex, and (3) colocalization of all pTDP deposits with annexin A11 (ANXA11).
Allegra Kawles, Caroline Nelson, Ivan Ayala, Elena Barbieri, Rudolph Castellani, Changiz Geula, Tamar Gefen, M. Marsel Mesulam   +7 more
wiley   +1 more source

DCC in the cerebral cortex is required for cognitive functions in mouse. [PDF]

Brain Pathol
Hu YQ, Liu WT, Wu Y, Hu ZB, Tao YC, Zhang Q, Chen JY, Li M, Hu L, Ding YQ.   +9 more
europepmc   +1 more source

Anatomical Associations Between Focal Mitochondrial Metabolism and Patterns of Neurodegeneration in Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) has a very specific neuroimaging signature, but the molecular underpinnings of the strikingly selective anatomic involvement have not elucidated to date. Accordingly, a large neuroimaging study was conducted with 258 participants to evaluate associations between patterns of neurodegeneration and focal ...
Marlene Tahedl, We Fong Siah, Efstratios Karavasilis, Jennifer C. Hengeveld, Mark A. Doherty, Russell L. McLaughlin, Orla Hardiman, Ee Ling Tan, Foteini Christidi, Jana Kleinerova, Peter Bede   +10 more
wiley   +1 more source

A quantitative analysis of bestrophin 1 cellular localization in mouse cerebral cortex. [PDF]

Acta Physiol (Oxf)
Di Palma M, Koh W, Lee CJ, Conti F.
europepmc   +1 more source

The Phenotypic Spectrum of Sporadic Creutzfeldt‐Jakob Disease Cortical Subtype

Annals of Neurology, EarlyView.
Objective The objective of this study was to characterize the phenotypic spectrum of the rare sporadic Creutzfeldt‐Jakob disease cortical subtype (sCJDMM/MV2C) in a large multicentric autopsy cohort. Methods We evaluated clinical histories, biofluid markers, brain diffusion‐weighted (DW)‐magnetic resonance imaging (MRI), and electroencephalogram (EEG ...
Simone Baiardi, Claudia Marina Vargiu, Brian S. Appleby, Marcelo Barria, Giuseppe Mario Bentivenga, Ignazio Calì, Benedetta Carlà, Mark Cohen, Armin Giese, Jochen Herms, Aino‐Minerva Kortelainen, Anna Ladogana, Angela Mammana, Diane Ritchie, Otto Windl, Sabina Capellari, Piero Parchi   +16 more
wiley   +1 more source

Serotonin 5-HT2A receptor expression is chronically decreased in the anterior cerebral cortex of male rats following repetitive low-level blast exposure. [PDF]

Front Neurol
De Gasperi R, Perez Garcia G, Gama Sosa MA, Perez GM, Abutarboush R, Kawoos U, Hof PR, Zhu CW, Ahlers ST, Elder GA.   +9 more
europepmc   +1 more source