Results 241 to 250 of about 1,027,636 (308)

Decoding chronic pain: the glutamate-GABA tug of war in the cerebral cortex. [PDF]

Front Mol Neurosci
Huang D, Dong YT, He LX, Zhou RZ, Zhou JX, Yang S, Yu SG.   +6 more
europepmc   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source

Mirror effect of genomic deletions and duplications on cognitive ability across the human cerebral cortex

Kumar K, Kazem S, Huguet G, Engchuan W, Kopal J, Renne T, Shanta O, Thiruvahindrapuram B, MacDonald J, Mollon J, Schultz LM, Knowles EEM, Porteous D, Davies G, Redmond P, Harris S, Cox S, Schumann G, Pausova Z, Greenwood C, Paus T, Scherer S, Almasy L, Sebat J, Glahn D, Dumas G, Jacquemont S.   +26 more
europepmc   +1 more source

Role of bisphenol A in the aberrant activation of ionotropic glutamate transporters in the cerebral cortex and altered behavioral responses in C57BL/6J mice. [PDF]

Front Toxicol
Khan J, Waseem M, Kamble K, Parvez S, Banerjee BD, Gupta S, Raisuddin S.   +6 more
europepmc   +1 more source

Meningeal Lymphatic LTBR Deficiency Links Spinal Cord Injury to Secondary Brain Pathology

Advanced Science, EarlyView.
Spinal cord injury (SCI) induces remote brain alterations beyond the injured spinal cord. This study links dysfunction of meningeal lymphatic vessels (mLVs) to neuroinflammation and neuronal injury after SCI. LTBR‐mediated lymphatic restoration improves meningeal lymphatic integrity and neurological outcomes, highlighting LTBR as a potential regulator ...
Yi Chen, Yu Tang, Chengpeng Hu, Xiaoyan Duan, LingXia Min, Boya Cong, Chao Ma, Mingliang Tan, Ya Luo, Pengfei Wei, Minpeng Xu, Zhou Feng, Jingming Hou   +12 more
wiley   +1 more source

The Pre-clinical Safety of Graphene-based Electrodes Implanted on Rat Cerebral Cortex. [PDF]

Exp Neurobiol
Kim G, Jeong H, Kim K, Lee S, Baeg E, Yang S, Kim B, Yang S.   +7 more
europepmc   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

Blood flow in the human cerebral cortex: Large-scale pial vascularization and 1D simulation. [PDF]

PLoS Comput Biol
Zilves EG, Müller LO, Talou GDM, Hachinski V, Spence JD, Blanco PJ.   +5 more
europepmc   +1 more source

Immune Modulatory Therapy for Severe Dengue Hemorrhagic Fever in a Patient With Mitochondrial Complex I Deficiency: A Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness, Ameya S. Walimbe, Emily R. Strouphauer, Michio Hirano, Alejandro D. Iglesias, Valentina Emmanuele, Caitlin C. Griffin, Sheldon L. Kaplan, William A. Gomes, Karen K. Moeller, Stephen F. Kralik, Fernando Scaglia   +11 more
wiley   +1 more source

Proteomic Analysis of Mouse Cerebral Cortex Following Experimental Ischemic Stroke: Identifying Novel Biomarkers of Damage and Repair. [PDF]

Cell Mol Neurobiol
Hamer D, Butorac A, Petrinec D, Berecki M, Mendes VM, Manadas B, Kelava V, K Hackenberger B, Glasnović A, Lovrić M, Gajović S, Dobrivojević Radmilović M.   +11 more
europepmc   +1 more source