Results 81 to 90 of about 1,638,797 (414)

Approximate invariance of metabolic energy per synapse during development in mammalian brains [PDF]

PLoS ONE 7(3): e33425 (2012), 2012
During mammalian development the cerebral metabolic rate correlates qualitatively with synaptogenesis, and both often exhibit bimodal temporal profiles. Despite these non-monotonic dependencies, it is found based on empirical data for different mammals that regional metabolic rate per synapse is approximately conserved from birth to adulthood for a ...
arxiv   +1 more source

How Forces Fold the Cerebral Cortex

Journal of Neuroscience, 2018
Improved understanding of the factors that govern folding of the cerebral cortex is desirable for many reasons. The existence of consistent patterns in folding within and between species suggests a fundamental role in brain function.
C. Kroenke, P. Bayly
semanticscholar   +1 more source

Global and regional brain metabolic scaling and its functional consequences [PDF]

, 2007
Background: Information processing in the brain requires large amounts of metabolic energy, the spatial distribution of which is highly heterogeneous reflecting complex activity patterns in the mammalian brain.
A Ames, A Devor, A Nehlig, A Nehlig, A Noda, A Zocchi, AG De Volder, AJ Hulbert, AJ Hulbert, AL Hodgkin, B Levant, B Siesjö, BG Cragg, BL Finlay, C Dube, C Kennedy, C Koch, C Redies, C Sahlin, CA Darveau, CC Sherwood, CF Stevens, CM Bishop, CR White, D Attwell, D Purves, DA Clark, DA Pelligrino, DB Chklovskii, DB Chklovskii, DD Clarke, DFS Rolfe, E Palombo, EM Nemoto, ER Kandel, ER Weibel, G Blomqvist, GB West, GF Striedter, H Haug, H Stephan, HT Chugani, I Quelven, I Vanzetta, J Astrup, J Blin, J Karbowski, J Karbowski, Jan Karbowski, JM Pell, JR Banavar, JW Prothero, K Meguro, K Schmidt-Nielsen, K Waschke, K Zhang, KH Harrison, KU Frerichs, L Sokoloff, LC Aiello, LJ Porrino, M Erecinska, M Kleiber, M Tsacopoulos, MA Hofman, N Turner, N Turner, NR Sibson, O Nakanishi, O Sporns, P Lennie, P Maquet, PH Harvey, PJ Magistretti, PL Else, PL Madsen, R Linde, R Lydic, R Olivares, R Stingele, RA Barton, RD Martin, RD Martin, RJ Haier, RJ Schwartzman, RK Porter, RK Suarez, S Herculano-Houzel, S Passero, S Shoham, SA Sheth, SB Laughlin, SC Hempleman, SJ Herdman, T Garland, V Bouilleret, V Braitenberg, WB Levy, WB Levy, WD Heiss, Z Wang   +100 more
core   +5 more sources

Correspondence of MRI and nTMS With EDSS in Multiple Sclerosis: Longitudinal Follow‐Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Considering the characteristics of multiple sclerosis (MS) disease and its impact on motor disability, this study aims to assess the functional integrity of the corticospinal tract by examining motor evoked potentials (MEPs), Expanded Disability Status Scale (EDSS) scores, magnetic resonance imaging (MRI) lesion counts, and ...
Antonia Bralić, Sanda Pavelin, Nikolina Pleić, Joško Šoda, Krešimir Dolić, Anita Markotić, Ana Ćurković Katić, Angela Mastelić, Nikolina Režić Mužinić, Jasna Duranović, Zlatko Kljajić, Ivona Stipica Safić, Zoran Đogaš, Maja Rogić Vidaković   +13 more
wiley   +1 more source

Interhemispheric asymmetry of the cerebral amino acid pool in rat with subtotal cerebral ischaemia

Анналы клинической и экспериментальной неврологии, 2019
The pathogenetic mechanisms of ischaemic stroke are complex and have not been fully studied, including the role of interhemispheric asymmetry in the brains biochemical organization. Study objective.
Yury E. Razvodovsky, Vitaliy Yu. Smirnov, Elina I. Troyan, Natalia E. Maksimovich   +3 more
doaj   +1 more source

Are the Neural Correlates of Consciousness in the Front or in the Back of the Cerebral Cortex? Clinical and Neuroimaging Evidence

Journal of Neuroscience, 2017
The role of the frontal cortex in consciousness remains a matter of debate. In this Perspective, we will critically review the clinical and neuroimaging evidence for the involvement of the front versus the back of the cortex in specifying conscious ...
M. Boly, M. Massimini, Naotsugu Tsuchiya, B. Postle, C. Koch, G. Tononi   +5 more
semanticscholar   +1 more source

Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats [PDF]

, 2007
Several studies suggest that cyclooxygenase (COX)-2 plays a pivotal role in the progression of ischemic brain damage. In the present study, we investigated the effects of selective inhibition of COX-2 with nimesulide (12 mg/kg) and selective inhibition ...
Candelario-Jalil, Eduardo, Fiebich, Bernd, Garcia-Cabrera, Michel, Gonzalez-Falcon, Armando, Leon, Olga Sonia   +4 more
core   +2 more sources

HPDL Variant Type Correlates With Clinical Disease Onset and Severity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recently, a mitochondrial encephalopathy due to biallelic HPDL variants was described, associated with a broad range of clinical manifestations ranging from severe, infantile‐onset neurodegeneration to adolescence‐onset hereditary spastic paraplegia. HPDL converts 4‐hydroxyphenylpyruvate acid (4‐HPPA) into 4‐hydroxymandelate (4‐HMA),
Eun Hye Lee, Olivia Kim‐Mcmanus, Jennifer H. Yang, Richard Haas, Maha S. Zaki, Ghada M. H. Abdel‐Salam, Yuji Nakamura, Mohamed S. Abdel‐Hamind, Darius Ebrahimi‐Fakhari, Julian E. Alecu, Nicola Brunetti‐Pierri, Varunvenkat M. Srinivasan, Vykuntaraju K. Gowda, Stephanie Gross, Yasemin Alanay, Paria Najarzadeh Totbati, Manya Yadavilli, Liana Friedman, Naomi Meave Ojeda, Joseph G. Gleeson   +19 more
wiley   +1 more source

Optogenetically Induced Spatiotemporal Gamma Oscillations in Visual Cortex [PDF]

arXiv, 2021
It has been hypothesized that Gamma cortical oscillations play important roles in numerous cognitive processes and may involve psychiatric conditions including anxiety, schizophrenia, and autism. Gamma rhythms are commonly observed in many brain regions during both waking and sleep states, yet their functions and mechanisms remain a matter of debate ...
arxiv  

Recurrent inhibition in the cerebral cortex [PDF]

Neuroscience Letters, 2019
Neuronal activity can be modulated by endogenous control mechanisms that either facilitate or suppress it. With this idea in mind, we attempted to evaluate and correlate spinal neuronal activity with the amplitude of corticogram (ECoG) event related potentials (ERP) in the presence of nociceptive stimulation in rats. We evaluated the ERP in response to
Javier Béjar-Alonso, Guadalupe Martínez-Lorenzana, Abimael González-Hernández, Ulises Cortes, Miguel Condés-Lara   +4 more
openaire   +4 more sources