Results 221 to 230 of about 129,062 (275)

Efficacy and Safety of Glibenclamide on Functional Outcomes and Cerebral Edema following Ischemic and Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Med Princ Pract
Hegazi A, Mohamed RG, Kashbour M, Hussein HO, Amin AM, Kassar O, Nashwan AJ, Abouelmagd ME.   +7 more
europepmc   +1 more source

The Efficacy and Safety of Glibenclamide in Improving Cerebral Edema and Neurological Outcomes in Stroke: a GRADE-Evaluated Systematic Review and Meta-analysis with Subgroup Analysis. [PDF]

Neurocrit Care
Mohammed HE, Haseeb ME, Bady Z, Nasser M, Meshref M.   +4 more
europepmc   +1 more source

Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries

Experimental Physiology, EarlyView.
Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted, Alex Aupetit, Karl Björling, Kristian Agmund Haanes, Susanne Syberg, Niklas Rye Jørgensen, Blanca I. Aldana, Hirotsugu Tsuchimochi, Mark T. Waddingham, Kristine Freude, James Todd Pearson, Lars Jørn Jensen   +11 more
wiley   +1 more source

Do auditory deviants evoke cortical state changes under anaesthesia? A proof‐of‐concept study

Experimental Physiology, EarlyView.
Abstract Context‐dependent sensory processing within the predictive coding framework relies on detecting mismatches between incoming stimuli and internal predictive models. Sensory deviants elicit prediction errors, seen as enhanced neural responses, that update these models and influence attention and behaviour.
Laura H Bohórquez, Manuel S Malmierca, Adam Hockley   +2 more
wiley   +1 more source

ESM‐1 and GBP‐1 are associated with endothelial dysfunction: emerging biomarkers or key players in the pathophysiology of preeclampsia?

The Journal of Physiology, EarlyView.
Abstract figure legend Endothelial specific molecule‐1 (ESM‐1) and guanylate binding protein‐1 (GBP‐1) are proteins that are produced by activated/dysfunctional endothelial cells and are increased and decreased, respectively, during preeclampsia. It remains to be established whether ESM‐1 and GBP‐1 could potentially be included as biomarkers for the ...
Ines Pronk, Joost H. N. Schuitemaker, Marijke M. Faas, Alexandra M. Smink   +3 more
wiley   +1 more source

Predicting cerebral edema in patients with spontaneous intracerebral hemorrhage using machine learning. [PDF]

Front Neurol
Xu J, Yuan C, Yu G, Li H, Dong Q, Mao D, Zhan C, Yan X.   +7 more
europepmc   +1 more source

The glia‐immune network: Astrocytes and oligodendrocytes as microglial co‐ordinators in health and disease

The Journal of Physiology, EarlyView.
Abstract figure legend The glia‐immune network involves the communication(s) of glia via immune signalling pathways. In neuro‐homeostasis these pathways have been shown to modulate key processes such as synaptic pruning and myelination. The dynamics of these processes is critical to CNS function.
Verity F. T. Mitchener, Millie J. Thackray, I. Lorena Arancibia‐Cárcamo   +2 more
wiley   +1 more source

Extracellular(Serum) Levels of Matrix Metalloproteinases in Pediatric Type 1 Diabetes Mellitus and Association with Diabetic Ketoacidosis and Cerebral Edema. [PDF]

Diabetes Metab Syndr Obes
Xu Q, Yang Y, Huang Q, Xie L, Feng Y, Yang L.   +5 more
europepmc   +1 more source

Astrocytes: Orchestrators of brain gas exchange and oxygen homeostasis

The Journal of Physiology, EarlyView.
Abstract figure legend Oxygen and carbon dioxide enter the body via breathing; in the brain astrocytes play a key role balancing oxygen delivery with carbon dioxide removal. Abstract If we consider neurons like muscles during exercise, the demand for oxygen (O2) and carbon dioxide (CO2) elimination is constantly changing.
Isabel N. Christie
wiley   +1 more source

Transcranial photobiomodulation with near‐infrared laser induces analgesia in rats

The Journal of Physiology, EarlyView.
Abstract figure legend Transcranial photobiomodulation (tPBM) with a 1064 nm laser alleviated pain. Local field potential (LFP) intensity markedly increased following formalin injection, indicating nociceptive activation. However, after tPBM, this formalin‐induced LFP hyperactivation was diminished. Meanwhile, tPBM preserved brain connectivity that was
Zhen Wang, Anqi Wu, Hanli Liu, Yuan Bo Peng   +3 more
wiley   +1 more source