Results 241 to 250 of about 1,314,540 (419)

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Treatment of sagittal sinus thrombosis associated with cerebral hemorrhage and intracranial hypertension. [PDF]

open access: bronze, 1988
Daniel F. Hanley   +4 more
openalex   +1 more source

Phenotype and surgical management of drug‐resistant epilepsy in patients with COL4A1 and COL4A2 variants

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To summarize the clinical features of collagen type IV alpha 1/2 chain (COL4A)1/2‐related epilepsy and the seizure outcomes of patients undergoing epilepsy surgery. Methods We retrospectively analyzed the clinical, electroencephalography, and neuroimaging data; genetic characteristics; surgical details; and prognosis of 8 patients (4
Jie Shi   +12 more
wiley   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

open access: yesExploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang   +4 more
wiley   +1 more source

Unilateral traumatic hemorrhage of the basal ganglion and bihemisferic cerebral infarction

open access: yesRomanian Neurosurgery, 2017
Among the various injuries caused by the cerebral tramatic lesion are trau- matic brain contusions. Hemorrhagic contusions of the basal ganglia are unusual.
Luis Rafael Moscote-Salazar   +3 more
doaj  

Controlled Ascent Rate Enhances Autophagy and Mitigates Acute Lung Injury in Rats Exposed to High‐Altitude Hypoxia by Inhibiting Oxidative Stress and Inflammation

open access: yesGlobal Challenges, EarlyView.
This study explores how gradual ascent rates reduce acute pulmonary injury in rats exposed to high‐altitude hypoxia by activating autophagy and suppressing oxidative stress and inflammation. Results show that controlled ascent effectively mitigates such injury, highlighting its potential as a preventive strategy.
Kairui Huang   +4 more
wiley   +1 more source

Proteome‐Wide Mendelian Randomization Identifies Candidate Causal Proteins for Cardiovascular Diseases

open access: yesAdvanced Genetics, EarlyView.
Here, causal relations are examined between 2940 plasma proteins and 19 cardiovascular diseases (CVD) using a human genetics‐based method. 218 proteins are found whose blood levels influence CVD risks, with about half being new discoveries and largely confirmed in an independent cohort.
Chen Li   +13 more
wiley   +1 more source

Narrative review of the prevalence and distribution of acute pain in children in the self‐care setting

open access: yesPaediatric and Neonatal Pain, Volume 4, Issue 4, Page 169-191, December 2022., 2022
Abstract Acute pain among children is common, yet it may be underestimated and undertreated if the pain is not recognized. Assessing and managing pediatric pain can be complicated, and as such, measuring the prevalence of acute pain in children can be challenging.
Nutan Shinde   +2 more
wiley   +1 more source

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