Results 151 to 160 of about 1,244,067 (429)

The spectrum of Ischemia-induced white matter injury varies with age [PDF]

open access: yes, 2013
Stroke is a neurological condition that targets the whole range of the human population, from the pre-term infant to the elderly and is a major cause of death worldwide (Ingall 2004).
Muscat, Richard   +2 more
core   +1 more source

Autophagy: a double-edged sword for neuronal survival after cerebral ischemia

open access: yesNeural Regeneration Research, 2014
Evidence suggests that autophagy may be a new therapeutic target for stroke, but whether activation of autophagy increases or decreases the rate of neuronal death is still under debate.
Wenqi Chen   +3 more
semanticscholar   +1 more source

The brain‐before‐heart strategy for coronary artery bypass grafting in the severely atherosclerotic aorta: A single‐institution experience

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1264-1271, December 2022., 2022
Abstract Background Severe atherosclerosis of the ascending aorta (SAA) in patients undergoing surgical revascularization by coronary artery bypass grafting (CABG) is becoming an increasing problem as more elderly patients are diagnosed with coronary artery disease.
Rakan I. Nazer, Ali M. Albarrati
wiley   +1 more source

Salidroside ameliorates cerebral ischemic injury and regulates the glutamate metabolism pathway in astrocytes

open access: yesFrontiers in Pharmacology
Background and AimSalidroside (SA) is the main active component of Rhodiola rosea L., with potential in treating cardiovascular and cerebrovascular diseases and cerebral ischemia.
Xiaoyu Zheng   +11 more
doaj   +1 more source

Protective Effect of Aerobic Exercise and Adenosine on Changes in Inflammation Mediators after Transient Ischemia of Common Carotid Arteries in Male Wistar Rats

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2021
Background and Objective: Stroke and cerebral ischemia are the second leading causes of death in the world. Currently, there are limited therapeutic interventions for patients with ischemia / reperfusion.
Zahra Eslami   +8 more
doaj  

Protective actions of des-acylated ghrelin on brain injury and blood-brain barrier disruption after stroke in mice [PDF]

open access: yes, 2016
The major ghrelin forms, acylated ghrelin and des-acylated ghrelin, are novel gastrointestinal hormones. Moreover, emerging evidence indicates that these peptides may have other functions including neuro- and vaso-protection.
Andrews, Zane B.   +8 more
core   +1 more source

Chrysophanol Inhibits NALP3 Inflammasome Activation and Ameliorates Cerebral Ischemia/Reperfusion in Mice

open access: yesMediators of Inflammation, 2014
The most effective way to contain cerebral ischemic injury is reperfusion; however, reperfusion itself may result in tissue injury, for which inflammatory damage is one of the main causative factors. NALP3 inflammasome is a multiprotein complex.
N. Zhang   +7 more
semanticscholar   +1 more source

Targeting Oxidative Stress and Inflammation to Prevent Ischemia-Reperfusion Injury

open access: yesFrontiers in Molecular Neuroscience, 2020
The cerebral ischemia injury can result in neuronal death and/or functional impairment, which leads to further damage and dysfunction after recovery of blood supply.
Liquan Wu   +6 more
semanticscholar   +1 more source

ARRB1/β-arrestin-1 mediates neuroprotection through coordination of BECN1-dependent autophagy in cerebral ischemia

open access: yesAutophagy, 2014
Autophagy, a highly conserved process conferring cytoprotection against stress, contributes to the progression of cerebral ischemia. β-arrestins are multifunctional proteins that mediate receptor desensitization and serve as important signaling scaffolds
Pei Wang   +8 more
semanticscholar   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

open access: yesAggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai   +6 more
wiley   +1 more source

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