Results 231 to 240 of about 355,372 (304)

Research progress of neurovascular units involved in ischemic stroke

open access: yesIbrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang   +4 more
wiley   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

open access: yesIbrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou   +6 more
wiley   +1 more source

Recent applications of magnetic iron oxide nanoparticles for cerebral blood volume quantification in functional magnetic resonance imaging

open access: yesIbrain, EarlyView.
This study explores the recent advances in the use of iron oxide nanoparticles (IONPs) in functional MRI (fMRI) for studying brain functions, specifically cerebral blood volume (CBV) measurements. It covers fMRI techniques, magnetic nanoparticle synthesis, coating methods, and their applications in CBV imaging, in comparison to other contrast agents in
Giorgio Capuzzello   +3 more
wiley   +1 more source

Evaluating predictive values of umbilical cord arterial lactate for adverse newborn outcomes among term‐births in northern Uganda: A cross sectional analytical study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 408-420, April 2025.
Abstract Objective Birth asphyxia is one of the leading causes of death for neonates worldwide. Lack of an objective cost effective test to predict poor newborn outcomes at birth affects the ability to respond appropriately. This study determined predictive values of umbilical cord arterial lactate in relation to adverse neonatal outcomes. Methods This
Elizabeth Ayebare   +7 more
wiley   +1 more source

Is amnioinfusion for intrapartum variable decelerations effective? Evaluation of the total deceleration area: A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Data regarding the efficiency of amnioinfusion in the presence of recurrent variable decelerations (VD) are limited. Total deceleration area (TDA) has been shown to be a useful indicator of both intrapartum fetal acid–base status and neonatal morbidity.
Gal Cohen   +6 more
wiley   +1 more source

Preterm meconium‐stained amniotic fluid: A red flag for infection and adverse perinatal outcomes

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Meconium‐stained amniotic fluid (MSAF) is uncommon in preterm deliveries and raises concerns about maternal and neonatal infectious risks. We aimed to evaluate maternal, perinatal, and microbiological outcomes in preterm deliveries complicated by MSAF compared to clear amniotic fluid (AF) and to assess outcomes in preterm versus term
Raneen Abu Shqara   +3 more
wiley   +1 more source

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