Results 251 to 260 of about 355,372 (304)

The protein arginine methyltransferase PRMT1 ameliorates cerebral ischemia-reperfusion injury by suppressing RIPK1-mediated necroptosis and apoptosis. [PDF]

open access: yesActa Pharm Sin B
Liu T   +15 more
europepmc   +1 more source

Role of nitric oxide in cerebral ischemia/reperfusion injury: A biomolecular overview.

open access: yesWorld J Clin Cases
Anaya-Prado R   +16 more
europepmc   +1 more source

Experimental cerebral ischemia

Neurosurgery, 1980
The basic concepts of the pathology and pathophysiology of cerebral ischemia are presented. Special emphasis is given to the changes that occur in the microcirculation and in autoregulation because of their primary role in the pathogenesis of cerebral infarction. The effects of adrenal steroids, barbiturates, and cerebral revascularization are reviewed.
Fernando G. Diaz, James I. Ausman
openaire   +3 more sources

MicroRNAs in Cerebral Ischemia

Translational Stroke Research, 2010
Pathogenesis of cerebral ischemia has so far been described in the context of proteins and the pathways that they regulate. The discovery of biomarkers has also been focussed mainly on proteins and to some extent on the mRNAs that encode them. The knowledge on the role of microRNAs in understanding the pathogenesis of cerebral ischemia is still at its ...
Lim, K.-Y.   +7 more
openaire   +2 more sources

Cerebral ischemia with CT

Computerized Tomography, 1977
One hundred fifty-eight patients with cerebral ischemia, and divided into four clinical groups were studied with CT. The results were correlated with those of angiography, scintigraphy and regional cerebral blood flow measurement. CT evolution was closely correlated with clinical and anatomical evolution.
P. Constant   +4 more
openaire   +3 more sources

Pharmacotherapy of cerebral ischemia

Expert Opinion on Pharmacotherapy, 2009
Ischemic stroke remains one of the leading causes of death and disability in the developed world. Despite many promising preclinical results, the only pharmacologic treatments proven effective in improving clinical outcome following ischemic stroke until now are administration of aspirin and acute thrombolysis using tissue-plasminogen activator.To ...
Andrew F. Ducruet   +5 more
openaire   +2 more sources

Cerebral Ischemia and Angiogenesis

Current Neurovascular Research, 2006
Angiogenesis occurs in a wide range of conditions. As ischemic tissue usually depends on collateral blood flow from newly produced vessels, acceleration of angiogenesis should be of therapeutic value to ischemic disorders. Indeed, therapeutic angiogenesis reduced tissue injury in myocardial or limb ischemia.
Atsushi Tsuchiya   +6 more
openaire   +3 more sources

Cerebral ischemia and inflammation

Current Opinion in Neurology, 2001
Cerebral ischemia is accompanied by a marked inflammatory reaction that is initiated by ischemia-induced expression of cytokines, adhesion molecules, and other inflammatory mediators, including prostanoids and nitric oxide. Preclinical studies suggest that interventions that are aimed at attenuating such inflammation reduce the progression of brain ...
Costantino Iadecola, Mihaela Alexander
openaire   +3 more sources

Polyamines in cerebral ischemia

Neurochemical Pathology, 1988
The present series of experiments was designed to study regional profiles of polyamines (putrescine, spermidine, and spermine) in reversible cerebral ischemia produced in rats and Mongolian gerbils. Polyamine profiles did not change during ischemia, but did following recirculation.
Joachim Hallmayer   +3 more
openaire   +3 more sources

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