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The protein arginine methyltransferase PRMT1 ameliorates cerebral ischemia-reperfusion injury by suppressing RIPK1-mediated necroptosis and apoptosis. [PDF]
Liu T+15 more
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Electroacupuncture Inhibits Ferroptosis by Modulating Iron Metabolism and Oxidative Stress to Alleviate Cerebral Ischemia-Reperfusion Injury. [PDF]
Liu Y, Wang Q, Hou Z, Gao Y, Li P.
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Role of nitric oxide in cerebral ischemia/reperfusion injury: A biomolecular overview.
Anaya-Prado R+16 more
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Experimental cerebral ischemia
Neurosurgery, 1980The basic concepts of the pathology and pathophysiology of cerebral ischemia are presented. Special emphasis is given to the changes that occur in the microcirculation and in autoregulation because of their primary role in the pathogenesis of cerebral infarction. The effects of adrenal steroids, barbiturates, and cerebral revascularization are reviewed.
Fernando G. Diaz, James I. Ausman
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MicroRNAs in Cerebral Ischemia
Translational Stroke Research, 2010Pathogenesis of cerebral ischemia has so far been described in the context of proteins and the pathways that they regulate. The discovery of biomarkers has also been focussed mainly on proteins and to some extent on the mRNAs that encode them. The knowledge on the role of microRNAs in understanding the pathogenesis of cerebral ischemia is still at its ...
Lim, K.-Y.+7 more
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Computerized Tomography, 1977
One hundred fifty-eight patients with cerebral ischemia, and divided into four clinical groups were studied with CT. The results were correlated with those of angiography, scintigraphy and regional cerebral blood flow measurement. CT evolution was closely correlated with clinical and anatomical evolution.
P. Constant+4 more
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One hundred fifty-eight patients with cerebral ischemia, and divided into four clinical groups were studied with CT. The results were correlated with those of angiography, scintigraphy and regional cerebral blood flow measurement. CT evolution was closely correlated with clinical and anatomical evolution.
P. Constant+4 more
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Pharmacotherapy of cerebral ischemia
Expert Opinion on Pharmacotherapy, 2009Ischemic stroke remains one of the leading causes of death and disability in the developed world. Despite many promising preclinical results, the only pharmacologic treatments proven effective in improving clinical outcome following ischemic stroke until now are administration of aspirin and acute thrombolysis using tissue-plasminogen activator.To ...
Andrew F. Ducruet+5 more
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Cerebral Ischemia and Angiogenesis
Current Neurovascular Research, 2006Angiogenesis occurs in a wide range of conditions. As ischemic tissue usually depends on collateral blood flow from newly produced vessels, acceleration of angiogenesis should be of therapeutic value to ischemic disorders. Indeed, therapeutic angiogenesis reduced tissue injury in myocardial or limb ischemia.
Atsushi Tsuchiya+6 more
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Cerebral ischemia and inflammation
Current Opinion in Neurology, 2001Cerebral ischemia is accompanied by a marked inflammatory reaction that is initiated by ischemia-induced expression of cytokines, adhesion molecules, and other inflammatory mediators, including prostanoids and nitric oxide. Preclinical studies suggest that interventions that are aimed at attenuating such inflammation reduce the progression of brain ...
Costantino Iadecola, Mihaela Alexander
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Polyamines in cerebral ischemia
Neurochemical Pathology, 1988The present series of experiments was designed to study regional profiles of polyamines (putrescine, spermidine, and spermine) in reversible cerebral ischemia produced in rats and Mongolian gerbils. Polyamine profiles did not change during ischemia, but did following recirculation.
Joachim Hallmayer+3 more
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