Results 261 to 270 of about 253,504 (317)
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Computerized Tomography, 1977
One hundred fifty-eight patients with cerebral ischemia, and divided into four clinical groups were studied with CT. The results were correlated with those of angiography, scintigraphy and regional cerebral blood flow measurement. CT evolution was closely correlated with clinical and anatomical evolution.
P, Constant +4 more
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One hundred fifty-eight patients with cerebral ischemia, and divided into four clinical groups were studied with CT. The results were correlated with those of angiography, scintigraphy and regional cerebral blood flow measurement. CT evolution was closely correlated with clinical and anatomical evolution.
P, Constant +4 more
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Cerebral Ischemia and Angiogenesis
Current Neurovascular Research, 2006Angiogenesis occurs in a wide range of conditions. As ischemic tissue usually depends on collateral blood flow from newly produced vessels, acceleration of angiogenesis should be of therapeutic value to ischemic disorders. Indeed, therapeutic angiogenesis reduced tissue injury in myocardial or limb ischemia.
Takeshi, Hayashi +6 more
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Polyamines in cerebral ischemia
Neurochemical Pathology, 1988The present series of experiments was designed to study regional profiles of polyamines (putrescine, spermidine, and spermine) in reversible cerebral ischemia produced in rats and Mongolian gerbils. Polyamine profiles did not change during ischemia, but did following recirculation.
W, Paschen +3 more
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Microvascular Research, 1977
Abstract Total cerebral ischemia often injures or alters the microcirculation. This injury is highly variable within microregions, often resulting in different patterns of reperfusion within 100 μm. There is a growing consensus that the microcirculation injury is a consequence of ischemic brain injury rather than an essential pathogenetic step to it.
J H, Halsey +3 more
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Abstract Total cerebral ischemia often injures or alters the microcirculation. This injury is highly variable within microregions, often resulting in different patterns of reperfusion within 100 μm. There is a growing consensus that the microcirculation injury is a consequence of ischemic brain injury rather than an essential pathogenetic step to it.
J H, Halsey +3 more
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Pharmacotherapy of cerebral ischemia
Expert Opinion on Pharmacotherapy, 2009Ischemic stroke remains one of the leading causes of death and disability in the developed world. Despite many promising preclinical results, the only pharmacologic treatments proven effective in improving clinical outcome following ischemic stroke until now are administration of aspirin and acute thrombolysis using tissue-plasminogen activator.To ...
Andrew F, Ducruet +5 more
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JAMA, 1961
Because of the sensitivity of the brain to hypoxia, acute cerebral ischemia due to operative or postoperative disruption of circulatory homeostasis, especially in older persons, should not be surprising. Six cases were selected to illustrate various peripheral circulatory mechanisms which, in conjunction with unrecognized preexisting cerebral vascular ...
R A, BURNS +5 more
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Because of the sensitivity of the brain to hypoxia, acute cerebral ischemia due to operative or postoperative disruption of circulatory homeostasis, especially in older persons, should not be surprising. Six cases were selected to illustrate various peripheral circulatory mechanisms which, in conjunction with unrecognized preexisting cerebral vascular ...
R A, BURNS +5 more
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Archives of Surgery, 1970
Eighteen of twenty patients with subclavian or innominate artery obstruction experienced episodes of transient cerebral arterial insufficiency; one patient suffered acute stroke and coma; all patients had angiographic evidence of subclavian or innominate artery obstruction; and most were shown to have retrograde flow in a vertebral artery. Two clinical
R L, Hewitt, R F, Weichert, T, Drapanas
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Eighteen of twenty patients with subclavian or innominate artery obstruction experienced episodes of transient cerebral arterial insufficiency; one patient suffered acute stroke and coma; all patients had angiographic evidence of subclavian or innominate artery obstruction; and most were shown to have retrograde flow in a vertebral artery. Two clinical
R L, Hewitt, R F, Weichert, T, Drapanas
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Electrophysiology of cerebral ischemia
Neuropharmacology, 2008Organized brain activity requires the coordinated firing of vast numbers of nerve cells. To maintain this, all these cells must be adequately polarized, their axons capable of conducting action potentials and releasing transmitters at an even greater numbers of synapses. Hence the often dire consequences of any interruption in the normal supply of O(2)
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Hemichannels in Cerebral Ischemia
Current Molecular Medicine, 2009Hemichannels are transmembrane channels that represent the functional subunits of gap junctions. Each hemichannel is composed of a connexin or pannexin hexamer and, after being transported to the membrane, remains unpaired until it is incorporated in a gap junction. Several studies have already provided evidence that gap junction-mediated intercellular
Panagiotis, Bargiotas +2 more
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Cerebral ischemia and inflammation
Current Opinion in Neurology, 2001Cerebral ischemia is accompanied by a marked inflammatory reaction that is initiated by ischemia-induced expression of cytokines, adhesion molecules, and other inflammatory mediators, including prostanoids and nitric oxide. Preclinical studies suggest that interventions that are aimed at attenuating such inflammation reduce the progression of brain ...
C, Iadecola, M, Alexander
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