Predictors of etiology and drug resistance in children with new‐onset focal seizures
Abstract Objective To examine the clinical features of new‐onset focal seizures in children and investigate clinical associations and predictors of underlying etiology and drug resistance. Methods Data were gathered from The Children's Hospital at Westmead admissions for patients aged 1 month to 18 years who presented with new‐onset focal seizures ...
Byoung Chan Lee +7 more
wiley +1 more source
Single-Cell RNA Sequencing Reveals Microglial Heterogeneity and Functional States After Cerebral Ischemia-Reperfusion Injury. [PDF]
Tang Y +10 more
europepmc +1 more source
Abstract The management of drug‐resistant epilepsy (DRE) in the pediatric population using neurostimulation of the centromedian (CM) nucleus of the thalamus (CMN) has been reported to be effective and safe. We present a case series of pediatric patients treated with responsive neurostimulation (RNS) and report on contact localization in relation to ...
Marian Michael Bercu +8 more
wiley +1 more source
Exploring the multi-repair effects of advanced biomimetic rapamycin nanoparticles on cerebral ischemia-reperfusion injury. [PDF]
Wang Y +11 more
europepmc +1 more source
Sudden unexpected death in epilepsy (SUDEP): Risk management of pediatric patients with epilepsy
Abstract Objective Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in people with epilepsy with an incidence of 1:1000. The primary risk factors for SUDEP are generalized or focal to bilateral tonic–clonic seizures. Preventive measures like nighttime monitoring devices and resuscitation training address modifiable risk factors.
Laura Lutz +3 more
wiley +1 more source
Uric Acid in Cerebral Ischemia: A Systematic Review of Its Biomarker Value and Role in Neuroprotection. [PDF]
Roman-Filip I +5 more
europepmc +1 more source
MFGM modulated gut microbiota accompanied by the increased serum RVD1 and AEA levels, which subsequently regulated the miRNA profile. This modulation alleviated neuroinflammation via suppressing the NLRP3 inflammasome signaling and microglial activation, thereby attenuating AD‐related cognitive impairment both in vivo and in vitro.
Han Gong +4 more
wiley +1 more source
Lithium reduces cerebral ischemia/reperfusion injury in dexamethasone-treated rats: The role of the PI3K/Akt pathway. [PDF]
Askar MM, Ibrahim IAAE, Mahmoud MF.
europepmc +1 more source
Transoral Styloidectomy Approach: A Systematic Review and Enhanced Endoscopic Approach
ABSTRACT Background Synthesize transoral styloidectomy approaches, highlight advantages, disadvantages, surgical outcomes, and describe an improved endoscopic transoral technique. Methods A systematic review of peer‐reviewed articles was conducted on November 11, 2025 in PubMed, Embase, the Cochrane Library, and Medline.
Nana‐Hawwa Abdul‐Rahman +4 more
wiley +1 more source
Electroacupuncture regulates neuronal ferroptosis and ferritinophagy through lysosomal-mediated TFEB activation in cerebral ischemia-reperfusion. [PDF]
Tang B +5 more
europepmc +1 more source

