Results 61 to 70 of about 823,827 (207)

Inhibition of the cGAS–STING pathway: contributing to the treatment of cerebral ischemia-reperfusion injury

open access: yesNeural Regeneration Research
The cGAS–STING pathway plays an important role in ischemia-reperfusion injury in the heart, liver, brain, and kidney, but its role and mechanisms in cerebral ischemia-reperfusion injury have not been systematically reviewed.
Hang Yang   +6 more
doaj   +1 more source

NDRG4 prevents cerebral ischemia/reperfusion injury by inhibiting neuronal apoptosis

open access: yesGenes and Diseases, 2019
Cerebral ischemia is a major cause of mortality and long-term morbidity worldwide. NDRG4 has been shown to protect against cerebral ischemia, although the underlying mechanisms remain largely unclear.
Lan Wen   +6 more
doaj   +1 more source

O nucleosídeo guanosina promove neuroproteção contra o estresse oxidativo e bioenergético em um modelo de isquemia cerebral in vitro [PDF]

open access: yes, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Bioquímica, Florianópolis, 2015As doenças vasculares cerebrais isquêmicas representam uma importante causa de mortalidade no ...
Thomaz, Daniel Tonial
core  

Cerebral Ischemia in Diabetics and Oxidative Stress

open access: yes, 2014
Cerebral ischemia is one of the major complications of diabetes. Eighty four percent of diabetics die from either heart disease or stroke (both cause cerebral ischemia).
Fuchs, Perry   +5 more
core   +1 more source

Effect of NLRP3 inflammasome on cerebral ischemia-reperfusion [PDF]

open access: yes, 2021
NLRP3 inflammasome is a polyprotein complex with complicated structure and unknown regulatory mechanism. Excessive activation of NLRP3 inflammasome is believed to be related to pathophysiological processes with multiple systemic diseases.
GUO Yan-qin, YIN Bo-kai, ZHANG Juan, HE Zhi
core  

Cerebral ischemia and histamine.

open access: yesFolia Pharmacologica Japonica, 2002
Cerebral ischemia induces excess release of glutamate and an increase in the intracellular Ca2+ concentration, which provoke catastrophic enzymatic processes leading to irreversible neuronal injury. Histamine plays the role of neurotransmitter in the central nervous system, and histaminergic fibers are widely distributed in the brain.
openaire   +3 more sources

Cerebral microdialysis: research technique or clinical tool [PDF]

open access: yes, 2006
Cerebral microdialysis is a well-established laboratory tool that is increasingly used as a bedside monitor to provide on-line analysis of brain tissue biochemistry during neuro-intensive care.
Tisdall, M.M., Smith, M.
core  

Effect of Saponin on Cerebral Edema Rate in An Animal Model of Stroke

open access: yesJournal of Mazandaran University of Medical Sciences, 2022
Background and purpose: Oxidative stress and neuroinflammation are the main causes of cerebral ischemia. Saponin with steroid or triterpenoid compounds with a sugar part has strong antioxidant and anti-inflammatory properties.
Elmira Shiri   +3 more
doaj  

Neuroprotective potential for mitigating ischemia-reperfusion-induced damage

open access: yesNeural Regeneration Research
Reperfusion following cerebral ischemia causes both structural and functional damage to brain tissue and could aggravate a patient’s condition; this phenomenon is known as cerebral ischemia-reperfusion injury.
Zi Ye   +8 more
doaj   +1 more source

Salidroside ameliorates cerebral ischemic injury and regulates the glutamate metabolism pathway in astrocytes

open access: yesFrontiers in Pharmacology
Background and AimSalidroside (SA) is the main active component of Rhodiola rosea L., with potential in treating cardiovascular and cerebrovascular diseases and cerebral ischemia.
Xiaoyu Zheng   +11 more
doaj   +1 more source

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