Results 141 to 150 of about 1,645,602 (269)

A shared inflammatory signature across severe malaria syndromes manifested by transcriptomic, proteomic and metabolomic analyses

Nature Communications
Factors governing the clinical trajectory of Plasmodium falciparum infection remain an important area of investigation. Here we present transcriptomic, proteomic and metabolomic analyses comparing clinical subtypes of severe Plasmodium falciparum malaria
Rafal S. Sobota, Emily M. Stucke, Drissa Coulibaly, Jonathan G. Lawton, Bryan E. Cummings, Savy Sebastian, Antoine Dara, James B. Munro, Amed Ouattara, Abdoulaye K. Kone, Bourama Kane, Karim Traoré, Bouréima Guindo, Bourama M. Tangara, Amadou Niangaly, Noah T. Ventimiglia, Modibo Daou, Issa Diarra, Youssouf Tolo, Mody Sissoko, Fayçal Maiga, Aichatou Diawara, Amidou Traore, Ali Thera, Matthew B. Laurens, Kirsten E. Lyke, Bourema Kouriba, Ogobara K. Doumbo, Christopher V. Plowe, David R. Goodlett, Joana C. Silva, Mahamadou A. Thera, Mark A. Travassos   +32 more
doaj   +1 more source

Murine malaria is associated with significant hearing impairment

Malaria Journal, 2010
Background Plasmodium falciparum malaria has been suspected to cause hearing loss. Developmental, cognitive and language disorders have been observed in children, surviving cerebral malaria.
Stephan Kurt, Reindl Markus, Glueckert Rudolf, Fischer Marlene, Dietmann Anelia, Lackner Peter, Kositz Christian H, Schmutzhard Joachim, Riechelmann Herbert, Schrott-Fischer Annelies, Schmutzhard Erich   +10 more
doaj   +1 more source

Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria

BMC Medicine, 2017
BackgroundExpression of group A and the A-like subset of group B Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is associated with severe malaria (SM).
E. Shabani, B. Hanisch, R. Opoka, T. Lavstsen, Chandy C. John   +4 more
semanticscholar   +1 more source

Congenital malaria in Uraba, Colombia

, 2011
: Background: Congenital malaria has been considered a rare event; however, recent reports have shown frequencies ranging from 3% to 54.2% among newborns of mothers who had suffered malaria during pregnancy.
Martínez Manrique, Enrique, Piñeros Jiménez, Juan Gabriel, Blair Trujillo, Silvia, Tobón Castaño, Alberto, Arboleda Naranjo, Margarita, Álvarez Sánchez, Luis Gonzalo   +5 more
core   +1 more source

Severe vivax malaria: Newly recognised or rediscovered? [PDF]

, 2008
Stephen Rogerson and Richard Carter discuss two new studies that challenge current dogma by suggesting that vivax malaria can cause severe ...
Carter Richard, Carter, Richard, Carter, R, Stephen J Rogerson, Richard Carter, Rogerson, Stephen J., Rogerson Stephen J, Rogerson, SJ   +7 more
core   +2 more sources

Differential plasma microvesicle and brain profiles of microRNA in experimental cerebral malaria

Malaria Journal, 2018
BackgroundCerebral malaria (CM) is a fatal complication of Plasmodium infection, mostly affecting children under the age of five in the sub-Saharan African region.
A. Cohen, Anna Zinger, N. Tiberti, G. Grau, V. Combes   +4 more
semanticscholar   +1 more source

Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase

Malaria Journal, 2017
Aspartate, which is converted from oxaloacetate (OAA) by aspartate aminotransferase, is considered an important precursor for purine salvage and pyrimidine de novo biosynthesis, and is thus indispensable for the growth of Plasmodium parasites at the ...
M. Niikura, Keisuke Komatsuya, S. Inoue, Risa Matsuda, H. Asahi, D. Inaoka, K. Kita, Fumie Kobayashi   +7 more
semanticscholar   +1 more source

IFN-γ-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain.

, 2012
It is well established that IFN-γ is required for the development of experimental cerebral malaria (ECM) during Plasmodium berghei ANKA infection of C57BL/6 mice. However, the temporal and tissue-specific cellular sources of IFN-γ during P.
Hunter, Christopher A, Couper, Kevin N, Riley, Eleanor M, Greig, Rachel, Blount, Daniel G, Blount, Daniel G., Stumhofer, Jason S, Hafalla, Julius CR, De Souza, J. Brian, Findlay, Emily Gwyer, Shaw, Tovah N, de Souza, J Brian, Riley, Eleanor M., Shaw, Tovah N., Stumhofer, Jason S., Hunter, Christopher A., Hafalla, Julius C R, Couper, Kevin N., Gwyer Findlay, Emily, Villegas-Mendez, Ana, de, Souza JB, Hunter, CA, Greig, R, Gwyer, Findlay E, Stumhofer, JS, Couper, KN, Blount, DG, Villegas-Mendez, A, Shaw, TN, Hafalla, JC, Riley, EM   +30 more
core   +1 more source

Planificación y gestión de proyectos en las asociaciones de daño cerebral

, 2021
La actividad de las entidades del movimiento asociativo de daño cerebral adquirido (DCA) tiene por objeto apoyar a las familias, reclamar atención sociosanitaria para las personas con daño cerebral adquirido; atenderlas y promover su inclusión social ...
Federación Española de Daño Cerebral
core  

Estimating the potential public health impact of seasonal malaria chemoprevention in African children. [PDF]

, 2012
Seasonal malaria chemoprevention, previously known as intermittent preventive treatment in children, is highly effective in areas with a short malaria transmission season.
Greenwood, Brian M, Roca-Feltrer, A., Ghani, Azra C, Cairns, M., Garske, Tini, Diallo, Diadier, Wilson, Anne L, Ghani, A.C., Greenwood, B.M., Milligan, Paul J, Diallo, D., Roca-Feltrer, Arantxa, Wilson, A.L., Milligan, P.J., Garske, T., Cairns, Matthew   +15 more
core   +1 more source