Results 131 to 140 of about 1,645,602 (269)

Targeting the IL33–NLRP3 axis improves therapy for experimental cerebral malaria

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Cerebral malaria (CM) is a neurological complication of malaria infection that, despite antimalarial drug treatment, results in fatality or neurodisability in approximately 25% of cases.
Patrick Strangward   +16 more
semanticscholar   +1 more source

Maternal Malaria and Gravidity Interact to Modify Infant Susceptibility to Malaria [PDF]

open access: yes, 2005
Background In endemic areas, placental malaria due to Plasmodium falciparum is most frequent and severe in first-time mothers, and increases the risk of infant mortality in their offspring.
Theonest K Mutabingwa   +20 more
core   +2 more sources

Actividades físico-deportivas y daño cerebral adquirido

open access: yes, 2021
El presente documento recoge el resumen y las conclusiones de un taller sobre actividades físico-deportivas y daño cerebral adquirido (DCA). También para las personas con DCA, la práctica de actividades deportivas puede constituir un importante factor de
Federación Española de Daño Cerebral
core  

miR-155 Modifies Inflammation, Endothelial Activation and Blood-Brain Barrier Dysfunction in Cerebral Malaria

open access: yesMolecular Medicine, 2017
miR-155 has been shown to participate in host response to infection and neuroinflammation via negative regulation of blood-brain barrier (BBB) integrity and T cell function.
K. Barker   +13 more
semanticscholar   +1 more source

Two complement receptor one alleles have opposing associations with cerebral malaria and interact with α+thalassaemia

open access: yeseLife, 2018
Malaria has been a major driving force in the evolution of the human genome. In sub-Saharan African populations, two neighbouring polymorphisms in the Complement Receptor One (CR1) gene, named Sl2 and McCb, occur at high frequencies, consistent with ...
D. Opi   +22 more
semanticscholar   +1 more source

Pathogenesis of Cerebral Malaria: New Diagnostic Tools, Biomarkers and Therapeutic Approaches

open access: yesFrontiers in Cellular and Infection Microbiology, 2015
Cerebral malaria is a severe neuropathological complication of Plasmodium falciparum infection. It results in high mortality and post-recovery neuro-cognitive disorders in children, even after appropriate treatment with effective anti-parasitic drugs ...
Praveen Kishore Sahu   +6 more
doaj   +1 more source

Children with cerebral malaria or severe malarial anaemia lack immunity to distinct variant surface antigen subsets

open access: yesScientific Reports, 2018
Variant surface antigens (VSAs) play a critical role in severe malaria pathogenesis. Defining gaps, or “lacunae”, in immunity to these Plasmodium falciparum antigens in children with severe malaria would improve our understanding of vulnerability to ...
Mark A. Travassos   +24 more
semanticscholar   +1 more source

samkioko/Cerebral-malaria-EV-RNAseq: v2

open access: yes
<p>These customised R scripts were used to analyse the RNA content of extracellular vesicles obtained from plasma of cerebral malaria patients</p ...
samkioko
core   +1 more source

Malaria in pregnancy.

open access: yes, 2005
Malaria in pregnancy is one of the major causes of maternal morbidity worldwide, and leads to poor birth outcomes. There is a complex interaction between pregnancy and parasite-all favour the parasite and disadvantage the pregnant woman.
Jesus R. Alvarez   +6 more
core   +1 more source

Malaria-filaria coinfection in mice makes malarial disease more severe unless filarial infection achieves patency [PDF]

open access: yes, 2005
Coinfections are common in natural populations, and the literature suggests that helminth coinfection readily affects how the immune system manages malaria.
Lamb, Tracey J   +8 more
core   +2 more sources

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