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Cerebral Salt Wasting Syndrome: A Review

Neurosurgery, 1996
Hyponatremia is frequently seen in neurosurgical patients and is often attributed to inappropriate secretion of antidiuretic hormone. A number of studies in recent years have shown that hyponatremia in many patients with intracranial disease may actually be caused by cerebral salt wasting, in which a renal loss of sodium leads to hyponatremia and a ...
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Cerebral Salt Wasting: Pathophysiology, Diagnosis, and Treatment

Neurosurgery Clinics of North America, 2010
Cerebral salt wasting (CSW) is a syndrome of hypovolemic hyponatremia caused by natriuresis and diuresis. The mechanisms underlying CSW have not been precisely delineated, although existing evidence strongly implicates abnormal elevations in circulating natriuretic peptides.
Alan H, Yee   +2 more
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Cerebral Salt-Wasting Syndrome: Does It Exist?

Nephron, 1999
Cerebral salt-wasting syndrome (CSWS) has been regarded as a misnomer of the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). We take the position that CSWS does exist and might be more common than SIADH. Differentiation between groups has been difficult because of overlapping signs, symptoms, and associated diseases.
J K, Maesaka, S, Gupta, S, Fishbane
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The role of fludrocortisone in a child with cerebral salt wasting

Pediatric Nephrology, 1998
Cerebral salt wasting (CSW) is a syndrome of hyponatremia due to excessive natriuresis described in patients with central nervous system insult. We present a 29-month-old black male with tuberculous meningitis who developed CSW with depressed mineralocorticoid activity. The patient required hypertonic saline and ionotropic support.
A, Sakarcan, J, Bocchini
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Cerebral Salt Wasting in a Child with Cervicothoracic Hematoma

Journal of Pediatric Endocrinology and Metabolism, 2008
Although the syndrome of inappropriate antidiuretic hormone secretion (SIADH) is commonly observed in patients with acute or chronic central nervous system (CNS) disorders, cerebral salt wasting (CSW) that results in hyponatremia has rarely been reported in children.
Enver, Simsek   +5 more
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Cerebral salt wasting in tuberculous meningitis: treatment with fludrocortisone

Annals of Tropical Paediatrics, 2005
Three cases of cerebral salt wasting complicating tuberculous meningitis are described. Diagnosis was based on hyponatraemia associated with high urinary sodium excretion and inappropriately high urine output in the presence of dehydration. Treatment with fludrocortisone resulted in sodium and fluid homeostasis.
Celik Ü.S.   +5 more
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Fludrocortisone Treatment in a Child with Severe Cerebral Salt Wasting

Pediatric Neurosurgery, 2001
Hyponatremia is a common complication of intracranial disease or surgery. An evaluation should be undertaken to determine whether cerebral salt wasting (CSW) or inappropriate secretion of antidiuretic hormone is present as a cause. Since the treatment principles are completely different in the two pathological states, differential diagnosis is very ...
Akalan, N   +4 more
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Cerebral Salt Wasting in Elderly Persons

Annals of Internal Medicine, 1987
Excerpt To the editors: Ishikawa and colleagues (1) have recently reported cases of hyponatremia with persistent urinary excretion of sodium in three elderly patients after head injury.
R. A. TANNEAU   +3 more
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Cerebral Salt-Wasting Associated With the Guillain-Barré Syndrome

Archives of Internal Medicine, 1965
INAPPROPRIATE secretion of antidiuretic hormone has been implicated as the cause of the hyponatremia and renal salt-wasting associated with certain cases of intracranial and intrathoracic disease. Cases of traumatic, infectious, and neoplastic intracranial disease, and of neoplastic thoracic disease have been associated with the salt-wasting syndrome ...
W C, COOPER, I J, GREEN, S P, WANG
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Mineralocorticoid Deficiency in Post-Operative Cerebral Salt Wasting

Journal of Pediatric Endocrinology and Metabolism, 2007
Acute hyponatremia, following neurosurgery, results from inappropriate antidiuretic hormone secretion (SIADH) or cerebral salt wasting (CSW). CSW is due to abnormally high atrial or brain natriuretic peptides (ANP, BNP), which block all stimulators of zona glomerulosa steroidogenesis, resulting in mineralocorticoid deficiency.
Dimitrios T, Papadimitriou   +9 more
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