Results 1 to 10 of about 6,146 (158)

Fludrocortisone Is Associated With a Higher Risk of All‐Cause Hospitalizations Compared With Midodrine in Patients With Orthostatic Hypotension

Journal of the American Heart Association, 2017
BackgroundOrthostatic hypotension causes ≈80 000 hospitalizations per year in the United States. Treatments for orthostatic hypotension include fludrocortisone, a mineralocorticoid analog that promotes sodium reabsorption; and midodrine, an α‐1 ...
Marie Griffin, Italo Biaggioni, CARLOS Grijalva   +2 more
exaly   +3 more sources

Hydrocortisone combined with fludrocortisone for treatment of adults with septic shock: an updated meta-analysis and systematic review. [PDF]

Front Med (Lausanne)
PurposeTo evaluate the efficacy and safety of hydrocortisone combined with fludrocortisone in the treatment of septic shock in adults.MethodsWe searched PubMed, Embase, Web of Science, and the Cochrane Library for studies on hydrocortisone combined with ...
Sun A, Gao X, Gao Z, Zhang Q, He W.
europepmc   +2 more sources

Impact of COVID‑19 infection on subsequent prescriptions of autonomic dysfunction pharmacotherapy: a nationwide propensity‑score‑matched Cohort study in Japan. [PDF]

Ann Med
Background Autonomic dysfunction, including orthostatic hypotension and postural tachycardia syndrome, has emerged as a COVID-19 complication.
Miyamori D, Ito M.
europepmc   +2 more sources

Efficacy and side effects of long-term treatment strategies of canine primary hypoadrenocorticism. [PDF]

Front Vet Sci
BackgroundHypoadrenocorticism (HA) with hyponatremia and hyperkalemia represents primary disease and indicates cortisol and aldosterone insufficiency. Treatment involves replacement of mineralocorticoids and glucocorticoids.
Dobosz DA, Zablotski Y, Wehner A.
europepmc   +2 more sources

Successful Management of Cerebral Salt-Wasting Syndrome in a Child With Epileptic Encephalopathy: A Case Report. [PDF]

Clin Case Rep
This case highlights the integral role of clinical pharmacists in the treatment process and suggests that fludrocortisone can serve as a safe and effective treatment option for CSWS in pediatric patients, especially when standard sodium supplementation ...
Zhang R, Deng Y, Li W.
europepmc   +2 more sources

Corticosteroids for sepsis and septic shock: a meta-analysis of 18 RCTs with dose-stratified and fludrocortisone subgroup evaluation. [PDF]

BMC Anesthesiol
Background The therapeutic benefit of corticosteroids in managing sepsis and septic shock remains controversial, particularly concerning optimal dosing strategies and the role of adjunctive fludrocortisone.
Ruyuan L, Zhangshun S, Hongling L, Jianling S.   +3 more
europepmc   +2 more sources

Control, Fludrocortisone or Midodrine for the treatment of Orthostatic Hypotension: CONFORM-OH pilot RCT and economic evaluation.

Health Technol Assess
Background Orthostatic hypotension is a significant drop in blood pressure upon standing upright. It is very common and can result in symptoms such as postural dizziness, fainting and falls.
Mossop H, Al Ashmori S, Sotire T, Clark E, Watson G, Witham M, Vale L, McGregor N, Phillipson J, Wason JM, Yarnall AJ, Hancock H, Kenny RA, Frith J.   +13 more
europepmc   +2 more sources

Correction: Hydrocortisone combined with fludrocortisone for treatment of adults with septic shock: an updated meta-analysis and systematic review. [PDF]

Front Med (Lausanne)
Sun A, Gao X, Gao Z, Zhang Q, He W.
europepmc   +2 more sources

Fludrocortisone Induces Aortic Pathologies in Mice

Biomolecules, 2022
Background and Objective: In an experiment designed to explore the mechanisms of fludrocortisone-induced high blood pressure, we serendipitously observed aortic aneurysms in mice infused with fludrocortisone.
Dien Ye, Congqing Wu, Hui Chen, Ching-Ling Liang, Deborah A. Howatt, Michael K. Franklin, Jessica J. Moorleghen, Samuel C. Tyagi, Estrellita Uijl, A. H. Jan Danser, Hisashi Sawada, Alan Daugherty, Hong S. Lu   +12 more
doaj   +1 more source

Cardiac and vascular effects of low-dose steroids during the early phase of septic shock: An echocardiographic study

Frontiers in Cardiovascular Medicine, 2022
BackgroundLow-dose steroids are known to increase arterial pressure during septic shock through restoration of vasopressor response to norepinephrine. However, their effects on cardiac performance and ventriculo-arterial coupling (VAC) have never been ...
François Bagate, François Bagate, Alexandre Coppens, Paul Masi, Paul Masi, Nicolas de Prost, Nicolas de Prost, Nicolas de Prost, Guillaume Carteaux, Guillaume Carteaux, Guillaume Carteaux, Keyvan Razazi, Keyvan Razazi, Armand Mekontso Dessap, Armand Mekontso Dessap, Armand Mekontso Dessap   +15 more
doaj   +1 more source