Results 171 to 180 of about 211,077 (381)

Association of pulsatility index with total burden of cerebral small vessel disease and cognitive impairment

open access: yesBrain and Behavior
Objective This study investigated the correlation between the pulsatility index (PI) of the middle cerebral artery with the total burden of cerebral small vessel disease and cognitive impairment.
Huijuan Wu   +6 more
doaj   +1 more source

Expanding the Tyrosine Kinase Domain of CSF1R? A Case Report From an Adult‐Onset Leukoencephalopathy

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Adult‐onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), also termed hereditary diffuse leukoencephalopathy with spheroids‐1 (HDLS1), results from mutations in the CSF1R gene and leads to progressive leukoencephalopathy.
Piervito Lopriore   +11 more
wiley   +1 more source

Retinal structure and vessel density changes in cerebral small vessel disease

open access: yesFrontiers in Neuroscience
BackgroundCerebral small vessel disease (CSVD) attaches people’s attention in recent years. In this study, we aim to explore retinal structure and vessel density changes in CSVD patients.MethodsWe collected information on retinal metrics assessed by ...
Dandan Wang   +8 more
doaj   +1 more source

Increased Aortic Pulse Wave Velocity Is Associated With Silent Cerebral Small-Vessel Disease in Hypertensive Patients [PDF]

open access: bronze, 2008
Léon H.G. Henskens   +7 more
openalex   +1 more source

Vascular dementia: Current concepts and nomenclature harmonization. [PDF]

open access: yes, 2012
Several types of cerebrovascular lesions are associated with cognitive decline, but the role of each type in dementia manifestation has yet to be determined.
Grinberg, Lea Tenenholz
core  

Establishment and evaluation of a novel rat model of the fourth ventricle hemorrhage

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, a novel rat model of fourth ventricle hemorrhage was established via autologous blood injection through the foramen of Magendie. Anesthetized rats were positioned in a stereotaxic apparatus with their heads tilted downward at an angle of approximately 20° relative to the vertical axis.
Chuhua Fu   +8 more
wiley   +1 more source

Clinical study of cerebral small vessel disease [PDF]

open access: yes, 2019
Ageing and hypertension are the main causes of cerebral small vessel disease (SVD) known until today. Endothelial dysfunction, rupture of blood-brain barrier (BBB) and protein elimination failure angiopathy have become important in its pathophysiology.
López Dequidt, Iria Alejandra
core   +1 more source

Association Between Vascular NOTCH3 Aggregation and Disease Severity in a CADASIL Cohort – Implications for NOTCH3 Variant‐Specific Disease Prediction

open access: yesAnnals of Neurology, EarlyView.
Objective Vascular NOTCH3 protein ectodomain aggregation is a pathological hallmark of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a monogenic small vessel disease typically caused by cysteine‐altering variants in NOTCH3.
Minne N. Cerfontaine   +10 more
wiley   +1 more source

Cerebral Small Vessel Disease-Induced Apolipoprotein E Leakage Is Associated With Alzheimer Disease and the Accumulation of Amyloid β-Protein in Perivascular Astrocytes [PDF]

open access: bronze, 2008
Sabrina Utter   +7 more
openalex   +1 more source

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