Objective This study investigated the correlation between the pulsatility index (PI) of the middle cerebral artery with the total burden of cerebral small vessel disease and cognitive impairment.
Huijuan Wu+6 more
doaj +1 more source
Asymmetric Dimethylarginine and Hypertension in Cerebral Small Vessel Disease [PDF]
Kazushi Tsuda
openalex +1 more source
Expanding the Tyrosine Kinase Domain of CSF1R? A Case Report From an Adult‐Onset Leukoencephalopathy
ABSTRACT Adult‐onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), also termed hereditary diffuse leukoencephalopathy with spheroids‐1 (HDLS1), results from mutations in the CSF1R gene and leads to progressive leukoencephalopathy.
Piervito Lopriore+11 more
wiley +1 more source
Retinal structure and vessel density changes in cerebral small vessel disease
BackgroundCerebral small vessel disease (CSVD) attaches people’s attention in recent years. In this study, we aim to explore retinal structure and vessel density changes in CSVD patients.MethodsWe collected information on retinal metrics assessed by ...
Dandan Wang+8 more
doaj +1 more source
Increased Aortic Pulse Wave Velocity Is Associated With Silent Cerebral Small-Vessel Disease in Hypertensive Patients [PDF]
Léon H.G. Henskens+7 more
openalex +1 more source
Vascular dementia: Current concepts and nomenclature harmonization. [PDF]
Several types of cerebrovascular lesions are associated with cognitive decline, but the role of each type in dementia manifestation has yet to be determined.
Grinberg, Lea Tenenholz
core
Establishment and evaluation of a novel rat model of the fourth ventricle hemorrhage
In this study, a novel rat model of fourth ventricle hemorrhage was established via autologous blood injection through the foramen of Magendie. Anesthetized rats were positioned in a stereotaxic apparatus with their heads tilted downward at an angle of approximately 20° relative to the vertical axis.
Chuhua Fu+8 more
wiley +1 more source
Clinical study of cerebral small vessel disease [PDF]
Ageing and hypertension are the main causes of cerebral small vessel disease (SVD) known until today. Endothelial dysfunction, rupture of blood-brain barrier (BBB) and protein elimination failure angiopathy have become important in its pathophysiology.
López Dequidt, Iria Alejandra
core +1 more source
Objective Vascular NOTCH3 protein ectodomain aggregation is a pathological hallmark of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a monogenic small vessel disease typically caused by cysteine‐altering variants in NOTCH3.
Minne N. Cerfontaine+10 more
wiley +1 more source
Cerebral Small Vessel Disease-Induced Apolipoprotein E Leakage Is Associated With Alzheimer Disease and the Accumulation of Amyloid β-Protein in Perivascular Astrocytes [PDF]
Sabrina Utter+7 more
openalex +1 more source