Results 181 to 190 of about 435,514 (353)

Cerebral Small Vessel Disease in Dementia and Depression: a prospective population-based MRI study [PDF]

, 2004
__Abstract__ Cerebral white matter lesions and asymptomatic brain infarcts are common in elderly people. These brain lesions are thought to result from cerebral small vessel disease, and their presence and severity increase with age and the presence
Prins, N.D. (Niels)
core  

Designed Biomaterial‐Enhanced Cell Transplantation for Neural Tissue Engineering

Aggregate, EarlyView.
Biomaterials offer a promising solution for cell transplantation in the central nervous system by creating a protective environment that enhances cell survival, integration, and functional recovery in preclinical models of neurological disorders. ABSTRACT Cell transplantation therapy in the central nervous system is hindered by limited survival and ...
Yun Tang, Alice Le Friec, Menglin Chen, Di Sun   +3 more
wiley   +1 more source

Diffusion imaging markers of cerebral small vessel disease [PDF]

, 2020
Diffusion magnetic resonance imaging (MRI) is widely used as a research tool to assess (subtle) alterations of the cerebral white matter. Measures derived from diffusion MRI appear to be valuable markers for cerebral small vessel disease (SVD).
Finsterwalder, Sofia
core   +2 more sources

Cognitive impairment and amygdala subregion volumes in elderly with cerebral small vessel disease: A large prospective cohort study

Neurobiology of Disease
Although the amygdala is associated with cognitive impairment resulting from cerebral small vessel disease, the relationship between alterations in amygdala structure and cerebral small vessel disease (CSVD) remains controversial. Given that the amygdala
Zhenyu Cheng, Linfeng Yang, Jing Li, Yiwen Chen, Pengcheng Liang, Yuanyuan Wang, Na Wang, Xinyue Zhang, Yian Gao, Chaofan Sui, Meng Li, Changhu Liang, Lingfei Guo   +12 more
doaj  

Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats

Science Translational Medicine, 2018
Endothelial cell–stabilizing drugs reverse white matter pathology in a rat model of cerebral small vessel disease. Defeating dysfunction Cerebral small vessel disease (SVD) affects arterioles in the brain, increasing risk of stroke and causing symptoms ...
Rikesh M. Rajani, Sophie Quick, S. Ruigrok, D. Graham, S. Harris, Benjamin F. J. Verhaaren, M. Fornage, S. Seshadri, S. Atanur, A. Dominiczak, Colin Smith, J. Wardlaw, Anna C. Williams   +12 more
semanticscholar   +1 more source

Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery

Aggregate, EarlyView.
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail, Guangze Yang, Yilong Fan, Yue Hui, Chun‐Xia Zhao, Yun Liu   +5 more
wiley   +1 more source

An NIR‐III 3P Excitable AIE Nanoprobe for High‐Quality Intravital Deep‐Brain Angiography

Aggregate, EarlyView.
A robust NIR‐III 3P excitable AIE probe was developed based on the proposed design strategy of π‐bridge manipulation to reconcile competing molecular parameters and optimize 3P fluorescence properties, which achieved optimal quality in intravital deep‐brain angiography among all reported organic 3P probes in terms of vascular imaging depth, SBR ...
Zhijun Zhang, Hui Cheng, Zengming Yang, Xiangquan Deng, Miaomiao Kang, Ping Qiu, Ke Wang, Dong Wang, Ben Zhong Tang   +8 more
wiley   +1 more source

Unruptured brain arteriovenous malformations causing seizures localize to one common brain network

Journal of Neuroscience Research, Volume 101, Issue 2, Page 245-255, February 2023., 2023
Seizures are a frequent symptom of unruptured brain arteriovenous malformations (bAVMs). Using VLSM and LNM analyses, we indicated that unruptured bAVMs causing seizures, while anatomically heterogeneous, were located within a common network, which could be a plausible neuroimaging biomarker for the prediction of possible seizures.
Shao‐Zhi Zhao, Yu‐Xin Zhao, Xiao‐Hua Liao, Ran Huo, Hao Li, Yu‐Ming Jiao, Jian‐Cong Weng, Jie Wang, Bing Liu, Yong Cao   +9 more
wiley   +1 more source

Quantitative Analysis of Multimodal MRI Markers and Clinical Risk Factors for Cerebral Small Vessel Disease Based on Deep Learning

International Journal of General Medicine
Zhiliang Zhang,1,* Zhongxiang Ding,2,* Fenyang Chen,2 Rui Hua,3 Jiaojiao Wu,3 Zhefan Shen,2 Feng Shi,3 Xiufang Xu1 1School of Medical Imaging, Hangzhou Medical College, Hangzhou, People’s Republic of China; 2Department of Radiology, Affiliated ...
Zhang Z, Ding Z, Chen F, Hua R, Wu J, Shen Z, Shi F, Xu X   +7 more
doaj  

Clonal Hematopoiesis and Thrombosis

American Journal of Hematology, EarlyView.
ABSTRACT Clonal hematopoiesis (CH) has been the focus of many research efforts in the last years and has emerged as a risk modifier for cardiovascular disease morbidity and mortality. While substantial evidence has accumulated regarding its impact on arterial system diseases, the connection with venous thrombosis has only recently been explored.
Cornelia Englisch, Cihan Ay
wiley   +1 more source