Cerebral small-vessel disease is associated with the severity of diabetic retinopathy in type 1 diabetes [PDF]
Introduction Cerebral small-vessel disease is common in neurologically asymptomatic individuals with type 1 diabetes. The retinal vasculature is thought to mirror the brain’s vasculature, but data on this association are limited in type 1 diabetes.
Turgut Tatlisumak+10 more
doaj +3 more sources
Cerebral Small Vessel Disease and Alzheimer's Disease: A Review [PDF]
Alzheimer's disease (AD) is the most common cause of dementia. Despite this, clear pathophysiology for AD has not been confirmed, and effective treatments are still not available.
Hae Won Kim+2 more
doaj +3 more sources
Genetics of common cerebral small vessel disease
Cerebral small vessel disease (cSVD) is a leading cause of ischaemic and haemorrhagic stroke and a major contributor to dementia. Covert cSVD, which is detectable with brain MRI but does not manifest as clinical stroke, is highly prevalent in the general population, particularly with increasing age.
Constance Bordes+3 more
semanticscholar +3 more sources
Cerebral Small Vessel Disease and Chronic Kidney Disease [PDF]
Chronic kidney disease, defined by a decreased glomerular filtration rate or albuminuria, is recognized as a major global health burden, mainly because it is an established risk factor for cardiovascular and cerebrovascular diseases. The magnitude of the
Kazunori Toyoda
doaj +4 more sources
Update of Immunosenescence in Cerebral Small Vessel Disease [PDF]
Aging of the central nervous system (CNS) is closely associated with chronic sterile low-grade inflammation in older organisms and related immune response.
Banghao Jian+5 more
doaj +3 more sources
Advanced Neuroimaging of Cerebral Small Vessel Disease [PDF]
Cerebral small vessel disease (SVD) is characterised by damage to deep grey and white matter structures of the brain and is responsible for a diverse range of clinical problems that include stroke and dementia. In this review, we describe advances in neuroimaging published since January 2015, mainly with magnetic resonance imaging (MRI), that, in ...
Blair, Gordon W.+4 more
openaire +6 more sources
Zooming in on cerebral small vessel function in small vessel diseases with 7T MRI: Rationale and design of the “ZOOM@SVDs” study [PDF]
Background: Cerebral small vessel diseases (SVDs) are a major cause of stroke and dementia. Yet, specific treatment strategies are lacking in part because of a limited understanding of the underlying disease processes.
Hilde van den Brink+16 more
doaj +5 more sources
Associations of Cerebral Small Vessel Disease and Chronic Kidney Disease in Patients With Acute Ischemic Stroke [PDF]
Background The relationship between chronic kidney disease (CKD) and cerebral small vessel disease has been inconsistently reported. In particular, there is a lack of research focusing on patients with acute ischemic stroke, a key area that could provide
Rentang Bi+6 more
doaj +2 more sources
Arterial Stiffness and Cerebral Small Vessel Disease
Background and Objective: Studies on relations between arterial stiffness and full spectrum of radiological features of cerebral small vessel disease (CSVD) are scarce.
Fei-Fei Zhai+14 more
doaj +3 more sources
Structural retinal changes in cerebral small vessel disease
Cerebral small vessel disease (CSVD) is an important contributor to cognitive impairment and stroke. Previous research has suggested associations with alterations in single retinal layers. We have assessed changes of all individual retinal layers in CSVD
S. Magdalena Langner+10 more
doaj +2 more sources