Results 21 to 30 of about 265,507 (241)

Inflammation and cerebral small vessel disease: A systematic review

Ageing Research Reviews, 2019
Inflammation is increasingly implicated as a risk factor for dementia, stroke, and small vessel disease (SVD). However, the underlying mechanisms and causative pathways remain unclear.
Audrey Low, Elijah Mak, James B Rowe Frcp   +2 more
exaly   +2 more sources

Different Characteristics of Incidental Diffusion‐Weighted Imaging‐Positive Lesions and Recent Small Subcortical Infarct in Patients With Cerebral Small Vessel Disease [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The mechanisms underlying covert versus symptomatic acute infarcts in cerebral small vessel disease are unclear. Methods Based on the multicenter Cerebral Small Vessel Disease Disability and Outcome Cohort Study, we consecutively enrolled ...
Zi‐Ang Pan, Ming Yao, Zi‐Yue Liu, Xing‐Qi Pan, Yan‐Yan Wang, Cheng‐Qian Li, Mei‐Jun Shu, Tain‐Qi Bao, Si‐Han Tang, Ding‐Ding Zhang, Li‐Xin Zhou, Jun Ni, Joanna M. Wardlaw, Fei Han, Yi‐Cheng Zhu   +14 more
doaj   +2 more sources

The glymphatic system and cerebral small vessel disease.

Journal of Stroke and Cerebrovascular Diseases
OBJECTIVES Cerebral small vessel disease is a group of pathologies in which alterations of the brain's blood vessels contribute to stroke and neurocognitive changes.
Phillip S. Ang, Douglas Zhang, S. Azizi, Salvador A. Norton de Matos, James R. Brorson   +4 more
semanticscholar   +4 more sources

Update of Immunosenescence in Cerebral Small Vessel Disease [PDF]

Frontiers in Immunology, 2020
Aging of the central nervous system (CNS) is closely associated with chronic sterile low-grade inflammation in older organisms and related immune response.
Banghao Jian, Mengyan Hu, Wei Cai, Wei Cai, Bingjun Zhang, Zhengqi Lu   +5 more
doaj   +3 more sources

Research progress of impaired cerebral hemodynamics in cerebral small vessel disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2021
Cerebral hemodynamic damage is an important mechanism in the pathogenesis of arteriolosclerotic cerebral small vessel disease (CSVD). The hemodynamic damage of cerebral small vessel disease includes the changes of blood pressure variability (BPV ...
LIU Na, XUE Yang, TANG Jie, ZHANG Miao⁃yi, REN Xue , FU Jian⁃hui   +5 more
doaj   +1 more source

Glymphatic clearance function in patients with cerebral small vessel disease

NeuroImage, 2021
Few studies have focused on the connection between glymphatic dysfunction and cerebral small vessel disease (CSVD), partially due to the lack of non-invasive methods to measure glymphatic function. We established modified index for diffusion tensor image
Wenhua Zhang, Ying Zhou, Jianan Wang, X. Gong, Zhicai Chen, Xuting Zhang, Jiong Cai, Siyan Chen, Lei Fang, Jian-zhong Sun, M. Lou   +10 more
semanticscholar   +1 more source

Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer’s disease

Molecular Neurodegeneration, 2023
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular injuries in cerebral large and small vessels and is a key driver of age-related cognitive decline.
Yasuteru Inoue, Francis Shue, G. Bu, T. Kanekiyo   +3 more
semanticscholar   +1 more source

Cerebral small vessel disease: Recent advances and future directions

International Journal of Stroke, 2022
Cerebral small vessel disease (SVD) causes lacunar stroke and intracerebral hemorrhage, and is the most common pathology underlying vascular cognitive impairment.
H. Markus, Frank Erik de Leeuw
semanticscholar   +1 more source

A Vessel for Change: Endothelial Dysfunction in Cerebral Small Vessel Disease [PDF]

Trends in Neurosciences, 2021
The blood vessels of the brain are lined with endothelial cells and it has been long known that these help to regulate blood flow to the brain. However, there is increasing evidence that these cells also interact with the surrounding brain tissue. These interactions change when the endothelial cells become dysfunctional and have an impact in diseases ...
Quick, S, Moss, J, Rajani, RM, Williams, A   +3 more
openaire   +4 more sources

Cerebral Small Vessel Disease, Hypertension, and Vascular Contributions to Cognitive Impairment and Dementia

HYPERTENSION, 2023
Hypertension-associated cerebral small vessel disease is a common finding in older people. Strongly associated with age and hypertension, small vessel disease is found at autopsy in over 50% of people aged ≥65 years, with a spectrum of clinical ...
A. Hainsworth, Hugh S. Markus, J. Schneider   +2 more
semanticscholar   +1 more source