Results 11 to 20 of about 127,750 (253)

Proteostasis in Cerebral Small Vessel Disease [PDF]

Frontiers in Neuroscience, 2019
Maintaining the homeostasis of proteins (proteostasis) by controlling their synthesis, folding and degradation is a central task of cells and tissues. The gradual decline of the capacity of the various proteostasis machineries, frequently in combination ...
Christof Haffner
doaj   +4 more sources

Hypercholesterolemia induced cerebral small vessel disease.

PLoS ONE, 2017
BackgroundWhile hypercholesterolemia plays a causative role for the development of ischemic stroke in large vessels, its significance for cerebral small vessel disease (CSVD) remains unclear.
Peter Kraft, Michael K Schuhmann, Cornelia Garz, Solveig Jandke, Daniela Urlaub, Stine Mencl, Alma Zernecke, Hans-Jochen Heinze, Roxana O Carare, Christoph Kleinschnitz, Stefanie Schreiber   +10 more
doaj   +4 more sources

Estrogen and cerebral small vessel disease

Chinese Medical Journal, 2021
Hui Gao, Lin-Yan Fu, Hong-Yu Mu, Chen Sang, Ning-Ning Wang   +4 more
doaj   +3 more sources

Dawson's Fingers in Cerebral Small Vessel Disease [PDF]

Frontiers in Neurology, 2020
To explore Dawson's fingers in cerebral small vessel disease (CSVD) and factors related to the development of Dawson's finger, we collected and analyzed clinical data of 65 patients with CSVD. We found a venous abnormality feature called Dawson's fingers
Aowei Lv, Zaiqiang Zhang, Ying Fu, Yaping Yan, Li Yang, Wenli Zhu   +5 more
doaj   +3 more sources

Update of Immunosenescence in Cerebral Small Vessel Disease [PDF]

Frontiers in Immunology, 2020
Aging of the central nervous system (CNS) is closely associated with chronic sterile low-grade inflammation in older organisms and related immune response.
Banghao Jian, Mengyan Hu, Wei Cai, Wei Cai, Bingjun Zhang, Zhengqi Lu   +5 more
doaj   +3 more sources

Cerebral small vessel disease: A review

Advances in Clinical and Experimental Medicine, 2021
Cerebral small vessel disease (CSVD) is the most common, chronic and progressive vascular disease. The changes affect arterioles, capillaries and small veins supplying the white matter and deep structures of the brain. It is the most common incidental finding on brain scans, especially in people over 80 years of age.
Justyna Chojdak-Łukasiewicz, Edyta Dziadkowiak, Anna Zimny, Bogusław Paradowski   +3 more
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A Vessel for Change: Endothelial Dysfunction in Cerebral Small Vessel Disease [PDF]

Trends in Neurosciences, 2021
The blood vessels of the brain are lined with endothelial cells and it has been long known that these help to regulate blood flow to the brain. However, there is increasing evidence that these cells also interact with the surrounding brain tissue. These interactions change when the endothelial cells become dysfunctional and have an impact in diseases ...
Quick, S, Moss, J, Rajani, RM, Williams, A   +3 more
openaire   +4 more sources

Cerebral small vessel disease: a bibliometric analysis

Journal of Molecular Neuroscience, 2022
Abstract Background Cerebral small vessel disease is a common neurological disease, and its incidence is increasing year by year worldwide. In recent years, research on cerebral small vessel disease has gained more and more attention. Our research aims to visualize publications to identify the hotspots and frontiers of cerebral small vessel ...
Ma, Wei, Yang, Yi-Bao, Xie, Ting-Ting, Xu, Yi, Liu, Na, Mo, Xue-Ni   +5 more
openaire   +2 more sources

Large-vessel correlates of cerebral small-vessel disease [PDF]

Neurology, 2013
Our aim was to investigate the relationship of carotid structure and function with MRI markers of cerebral ischemic small-vessel disease.The study comprised 1,800 participants (aged 72.5 ± 4.1 years, 59.4% women) from the 3C-Dijon Study, a population-based, prospective cohort study, who had undergone quantitative brain MRI and carotid ultrasound.
Brisset, Marion, Boutouyrie, Pierre, Pico, Fernando, Zhu, Yicheng, Zureik, Mahmoud, Schilling, Sabrina, Dufouil, Carole, Mazoyer, Bernard, Laurent, Stéphane, Tzourio, Christophe, Debette, Stéphanie   +10 more
openaire   +3 more sources

Gait in Elderly With Cerebral Small Vessel Disease [PDF]

Stroke, 2010
Background and Purpose— Gait disorders are common in the elderly and are related to loss of functional independence and death. White matter lesions (WMLs) may be related, but only a minority of individuals with WMLs has gait disorders.
de Laat, K.F., van Norden, A.G.W., Gons, R.A.R., van Oudheusden, L.J.B., van Uden, I.W.M., Bloem, B.R., Zwiers, M.P., Zwiers, M.P., de Leeuw, F.E.   +8 more
openaire   +5 more sources