Results 1 to 10 of about 156,008 (150)

Genetic considerations in cerebral small vessel diseases. [PDF]

Front Neurol, 2023
Cerebral small vessel disease (CSVD) encompasses a broad clinical spectrum united by pathology of the small vessels of the brain. CSVD is commonly identified using brain magnetic resonance imaging with well characterized markers including covert infarcts,
Bhagat R, Marini S, Romero JR.
europepmc   +3 more sources

Zooming in on cerebral small vessel function in small vessel diseases with 7T MRI: Rationale and design of the “ZOOM@SVDs” study

Cerebral Circulation - Cognition and Behavior, 2021
Background: Cerebral small vessel diseases (SVDs) are a major cause of stroke and dementia. Yet, specific treatment strategies are lacking in part because of a limited understanding of the underlying disease processes.
Hilde van den Brink, Anna Kopczak, Tine Arts, Laurien Onkenhout, Jeroen C.W. Siero, Jaco J.M. Zwanenburg, Marco Duering, Gordon W. Blair, Fergus N. Doubal, Michael S. Stringer, Michael J. Thrippleton, Hugo J. Kuijf, Alberto de Luca, Jeroen Hendrikse, Joanna M. Wardlaw, Martin Dichgans, Geert Jan Biessels   +16 more
doaj   +2 more sources

Heterogeneous blood-brain barrier dysfunction in cerebral small vessel diseases. [PDF]

Alzheimers Dement
We explored how blood‐brain barrier (BBB) leakage rate of gadolinium chelates (Ktrans) and BBB water exchange rate (kw) varied in cerebral small vessel disease (cSVD) subtypes.
Ying Y, Li Y, Yao T, Shao X, Tang W, Montagne A, Chabriat H, Wang DJJ, Wang C, Yang Q, Cheng X.   +10 more
europepmc   +2 more sources

Association between Computed Tomographic Biomarkers of Cerebral Small Vessel Diseases and Long-Term Outcome after Spontaneous Intracerebral Hemorrhage. [PDF]

Ann Neurol, 2021
A study was undertaken to assess whether cerebral small vessel disease (SVD) computed tomographic (CT) biomarkers are associated with long‐term outcome after intracerebral hemorrhage.
Rodrigues MA, E Samarasekera N, Lerpiniere C, Perry LA, Moullaali TJ, J M Loan J, Wardlaw JM, Al-Shahi Salman R, Lothian Audit of the Treatment of Cerebral Haemorrhage Collaborators.   +8 more
europepmc   +2 more sources

Rationale and design of a longitudinal study of cerebral small vessel diseases, clinical and imaging outcomes in patients presenting with mild ischaemic stroke: Mild Stroke Study 3. [PDF]

Eur Stroke J, 2021
Background Cerebral small vessel disease is a major cause of dementia and stroke, visible on brain magnetic resonance imaging. Recent data suggest that small vessel disease lesions may be dynamic, damage extends into normal-appearing brain and ...
Clancy U, Garcia DJ, Stringer MS, Thrippleton MJ, Valdés-Hernández MC, Wiseman S, Hamilton OK, Chappell FM, Brown R, Blair GW, Hewins W, Sleight E, Ballerini L, Bastin ME, Maniega SM, MacGillivray T, Hetherington K, Hamid C, Arteaga C, Morgan AG, Manning C, Backhouse E, Hamilton I, Job D, Marshall I, Doubal FN, Wardlaw JM.   +26 more
europepmc   +2 more sources

Brain atrophy in cerebral small vessel diseases: Extent, consequences, technical limitations and perspectives: The HARNESS initiative. [PDF]

J Cereb Blood Flow Metab, 2020
Brain atrophy is increasingly evaluated in cerebral small vessel diseases. We aim at systematically reviewing the available data regarding its extent, correlates and cognitive consequences.
De Guio F, Duering M, Fazekas F, De Leeuw FE, Greenberg SM, Pantoni L, Aghetti A, Smith EE, Wardlaw J, Jouvent E.   +9 more
europepmc   +2 more sources

Essential nutrients and cerebral small vessel diseases: a two-sample Mendelian randomization study. [PDF]

Front Nutr, 2023
BackgroundPrevious studies have suggested a potential association between nutrients and cerebral small vessel disease (CSVD), but this association has not been fully addressed.ObjectWe intended to clarify the causal associations between four categories ...
Li J, Xia K, Wang Z, Liu Y, Tong Y, Wang Y, Zhou Y, Zhang L, Tang L, Fan D, Yang Q.   +10 more
europepmc   +2 more sources

Optical coherence tomography angiography as a potential screening tool for cerebral small vessel diseases. [PDF]

Alzheimers Res Ther, 2020
Background The retina and the brain share anatomic, embryologic, and physiologic characteristics. Therefore, retinal imaging in patients with brain disorders has been of significant interest. Using optical coherence tomography angiography (OCTA), a novel
Lee JY, Kim JP, Jang H, Kim J, Kang SH, Kim JS, Lee J, Jung YH, Na DL, Seo SW, Oh SY, Kim HJ.   +11 more
europepmc   +2 more sources

Exploring the association between Cerebral small-vessel diseases and motor symptoms in Parkinson's disease. [PDF]

Brain Behav, 2019
to explore the association between cerebral small‐vessel diseases (CSVDs) and motor symptoms in Parkinson's disease (PD).
Wan Y, Hu W, Gan J, Song L, Wu N, Chen Y, Liu Z.   +6 more
europepmc   +2 more sources

Segmentation of incident lacunes during the course of ischemic cerebral small vessel diseases. [PDF]

Front Neurol, 2023
BackgroundLacunes represent key imaging markers of cerebral small vessel diseases (cSVDs). During their progression, incident lacunes are related to stroke manifestations and contribute to progressive cognitive and/or motor decline. Assessing new lesions
Lebenberg J, Zhang R, Grosset L, Guichard JP, Fernandes F, Jouvent E, Chabriat H.   +6 more
europepmc   +2 more sources