Genetic considerations in cerebral small vessel diseases. [PDF]
Cerebral small vessel disease (CSVD) encompasses a broad clinical spectrum united by pathology of the small vessels of the brain. CSVD is commonly identified using brain magnetic resonance imaging with well characterized markers including covert infarcts,
Bhagat R, Marini S, Romero JR.
europepmc +3 more sources
Background: Cerebral small vessel diseases (SVDs) are a major cause of stroke and dementia. Yet, specific treatment strategies are lacking in part because of a limited understanding of the underlying disease processes.
Hilde van den Brink +16 more
doaj +2 more sources
Heterogeneous blood-brain barrier dysfunction in cerebral small vessel diseases. [PDF]
We explored how blood‐brain barrier (BBB) leakage rate of gadolinium chelates (Ktrans) and BBB water exchange rate (kw) varied in cerebral small vessel disease (cSVD) subtypes.
Ying Y +10 more
europepmc +2 more sources
Association between Computed Tomographic Biomarkers of Cerebral Small Vessel Diseases and Long-Term Outcome after Spontaneous Intracerebral Hemorrhage. [PDF]
A study was undertaken to assess whether cerebral small vessel disease (SVD) computed tomographic (CT) biomarkers are associated with long‐term outcome after intracerebral hemorrhage.
Rodrigues MA +8 more
europepmc +2 more sources
Rationale and design of a longitudinal study of cerebral small vessel diseases, clinical and imaging outcomes in patients presenting with mild ischaemic stroke: Mild Stroke Study 3. [PDF]
Background Cerebral small vessel disease is a major cause of dementia and stroke, visible on brain magnetic resonance imaging. Recent data suggest that small vessel disease lesions may be dynamic, damage extends into normal-appearing brain and ...
Clancy U +26 more
europepmc +2 more sources
Brain atrophy in cerebral small vessel diseases: Extent, consequences, technical limitations and perspectives: The HARNESS initiative. [PDF]
Brain atrophy is increasingly evaluated in cerebral small vessel diseases. We aim at systematically reviewing the available data regarding its extent, correlates and cognitive consequences.
De Guio F +9 more
europepmc +2 more sources
Essential nutrients and cerebral small vessel diseases: a two-sample Mendelian randomization study. [PDF]
BackgroundPrevious studies have suggested a potential association between nutrients and cerebral small vessel disease (CSVD), but this association has not been fully addressed.ObjectWe intended to clarify the causal associations between four categories ...
Li J +10 more
europepmc +2 more sources
Optical coherence tomography angiography as a potential screening tool for cerebral small vessel diseases. [PDF]
Background The retina and the brain share anatomic, embryologic, and physiologic characteristics. Therefore, retinal imaging in patients with brain disorders has been of significant interest. Using optical coherence tomography angiography (OCTA), a novel
Lee JY +11 more
europepmc +2 more sources
Exploring the association between Cerebral small-vessel diseases and motor symptoms in Parkinson's disease. [PDF]
to explore the association between cerebral small‐vessel diseases (CSVDs) and motor symptoms in Parkinson's disease (PD).
Wan Y +6 more
europepmc +2 more sources
Segmentation of incident lacunes during the course of ischemic cerebral small vessel diseases. [PDF]
BackgroundLacunes represent key imaging markers of cerebral small vessel diseases (cSVDs). During their progression, incident lacunes are related to stroke manifestations and contribute to progressive cognitive and/or motor decline. Assessing new lesions
Lebenberg J +6 more
europepmc +2 more sources

