Results 31 to 40 of about 98,114 (150)
Imaging scoring methods for cerebral small vessel disease
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 The pathogenesis of cerebral small vessel disease (CSVD) is not yet clear, and there is no effective treatment method at present. MRI is an important imaging in diagnosing.
PAN Xi⁃juan +2 more
doaj +1 more source
Research progress of cerebral small vessel disease associated with immunoinflammatory mechanisms
Chinese Journal of Contemporary Neurology and Neurosurgery, 2021 Cerebral small vessel disease (CSVD) is a type of intracranial vascular disease characterized by recurrent stroke and neurodegenerative progression. The pathogenesis of CSVD is still unclear, and immunoinflammatory mechanisms such as blood⁃brain barrier ...
ZHANG Hai⁃bo, GUO Yan⁃jun
doaj +1 more source
Genetics of Cerebral Small Vessel Disease [PDF]
Journal of Stroke, 2015 Cerebral small vessel disease (SVD) is an important cause of stroke and cognitive impairment among the elderly and is a more frequent cause of stroke in Asia than in the US or Europe. Although traditional risk factors such as hypertension or diabetes mellitus are important in the development of cerebral SVD, the exact pathogenesis is still uncertain ...
openaire +3 more sources
Cerebral Venous Reflux and Dilated Basal Ganglia Perivascular Space in Hypertensive Intracerebral Hemorrhage [PDF]
Journal of Stroke, 2022 Background and Purpose Cerebral venous flow alterations potentially contribute to age-related white matter changes, but their role in small vessel disease has not been investigated. Methods This study included 297 patients with hypertensive intracerebral
Hsin-Hsi Tsai +4 more
doaj +1 more source
Proteostasis in Cerebral Small Vessel Disease [PDF]
Frontiers in Neuroscience, 2019 Maintaining the homeostasis of proteins (proteostasis) by controlling their synthesis, folding and degradation is a central task of cells and tissues. The gradual decline of the capacity of the various proteostasis machineries, frequently in combination with their overload through mutated, aggregation-prone proteins, is increasingly recognized as an ...
openaire +4 more sources
Cerebral small vessel disease: A glymphopathy?
Current Opinion in Neurobiology, 2022 Small vessel disease (SVD) is a common instigator of dementia in the aging population. The hallmarks of SVD are enlargement of the perivascular spaces and white matter hyperintensities. The latter represents local fluid accumulation in white matter that either subsides or develops into lacunar infarcts.
Benveniste, Helene, Nedergaard, Maiken
openaire +3 more sources
Zhongguo cuzhong zazhi, 2019 增龄相关性脑小血管病谱系（spectrum o f a ge-related cerebral small vessel diseases， ArCSVDS）是指随着年龄的增长，脑小动脉、微动脉、毛细血管、微静脉、小静脉出现老化的一组脑 小血管病（cerebral small vessel disease，CSVD），包括深穿支动脉病（deep perforating arteriopathy，DPA） 和β淀粉样蛋白（β-amyloid，Aβ）有关的脑淀粉样血管病（cerebral amyloid ...
陆正齐，宋康宇
doaj +1 more source
A novel COL4A1 variant associated with recurrent epistaxis and glioblastoma
Human Genome Variation, 2021 COL4A1-related disorders are characterized by a higher incidence of cerebral hemorrhage than other hereditary cerebral small vessel diseases. Accumulating data have shown broad phenotypic variations, and extracerebral hemorrhages have been linked to ...
Kohei Muto +12 more
doaj +1 more source
Cerebral Small Vessel Disease and Alzheimer's Disease: A Review
Frontiers in Neurology, 2020 Alzheimer's disease (AD) is the most common cause of dementia. Despite this, clear pathophysiology for AD has not been confirmed, and effective treatments are still not available.
Hae Won Kim +2 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Previous studies have integrated genome‐wide association studies with expression quantitative trait locus (eQTL) data from bulk tissues to identify stroke susceptibility genes. However, eQTL data exhibit high cell‐type specificity, and genetic
Yijie He +8 more
doaj +1 more source