Results 31 to 40 of about 7,881,496 (248)

A Systematic Review of WNT Signaling in Endothelial Cell Oligodendrocyte Interactions:Potential Relevance to Cerebral Small Vessel Disease [PDF]

, 2020
Key pathological features of cerebral small vessel disease (cSVD) include impairment of the blood brain barrier (BBB) and the progression of white matter lesions (WMLs) amongst other structural lesions, leading to the clinical manifestations of cSVD. The
Fulton, Daniel, Blankesteijn, W. Matthijs, Foulquier, Sebastien; id_orcid, Daniel Fulton, Ahmed, Zubair, Foulquier, Sébastien, Zubair Ahmed, Manukjan, Narek, Fulton, Daniel; id_orcid, W. Matthijs Blankesteijn, Narek Manukjan, Sébastien Foulquier, Ahmed, Zubair; id_orcid   +12 more
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The relation between total cerebral small vessel disease burden and gait impairment in patients with minor stroke [PDF]

, 2017
Background and aims Individual MRI markers of cerebral small vessel disease are associated with gait impairment. The impact of total cerebral small vessel disease-related brain damage, expressed by a cerebral small vessel disease MRI burden score, on ...
McHutchison, Caroline, Martin S Dennis, Cvoro, V., Cvoro, Vera, van Oostenbrugge, Robert J., Staals, Julie, Chappell, F., Francesca Chappell, Staals, J., Julie Staals, Loos, C. M., Makin, Stephen D. J., Joanna M Wardlaw, Dennis, M.S., Dennis, Martin S., Wardlaw, J. M., Caroline McHutchison, Dennis, Martin, Vera Cvoro, McHutchison, C., Loos, Caroline M. J., Makin, Stephen, Makin, S. D., Stephen DJ Makin, Robert J van Oostenbrugge, Chappell, Francesca, Wardlaw, Joanna M., Wardlaw, Joanna, Caroline MJ Loos, Loos, Caroline M.J., van Oostenbrugge, Robert J, van Oostenbrugge, R. J.   +31 more
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Imaging scoring methods for cerebral small vessel disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
The pathogenesis of cerebral small vessel disease (CSVD) is not yet clear, and there is no effective treatment method at present. MRI is an important imaging in diagnosing.
PAN Xi⁃juan, XING Ying⁃qi, LIU Yu⁃mei   +2 more
doaj   +1 more source

Depression in small-vessel disease relates to white matter ultrastructural damage, not disability. [PDF]

, 2014
OBJECTIVE: To determine whether cerebral small-vessel disease (SVD) is a specific risk factor for depression, whether any association is mediated via white matter damage, and to study the role of depressive symptoms and disability on quality of life (QoL)
Morris, RG, Brookes, RL, Lawrence, AJ, Morris, Robin G., Lawrence, Andrew J.; id_orcid, Herbert, Vanessa, Herbert, V, Brookes, Rebecca L., Markus, Hugh S., Markus, HS   +9 more
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Research progress of cerebral small vessel disease associated with immunoinflammatory mechanisms

Chinese Journal of Contemporary Neurology and Neurosurgery, 2021
Cerebral small vessel disease (CSVD) is a type of intracranial vascular disease characterized by recurrent stroke and neurodegenerative progression. The pathogenesis of CSVD is still unclear, and immunoinflammatory mechanisms such as blood⁃brain barrier ...
ZHANG Hai⁃bo, GUO Yan⁃jun
doaj   +1 more source

Early life characteristics and late life burden of cerebral small vessel disease in the Lothian Birth Cohort 1936 [PDF]

, 2016
It is unknown whether relations between early-life factors and overall health in later life apply to burden of cerebral small vessel disease (cSVD), a major cause of stroke and dementia.
Shenkin, Susan, McHutchison, Caroline, Gow, Alan, Field, Thalia S., Corley, Janie, Deary, Ian J., Pattie, Alison, Doubal, Fergus N., Deary, Ian, Backhouse, Ellen, Gow, Alan J.; id_orcid, Gow, Alan J., Cvoro, Vera, Staals, Julie, Johnson, Wendy, Cox, Simon, Doubal, Fergus, Morris, Zoe, Wardlaw, Joanna M., Wardlaw, Joanna, Shenkin, Susan; id_orcid, Bastin, Mark   +21 more
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Cerebral Venous Reflux and Dilated Basal Ganglia Perivascular Space in Hypertensive Intracerebral Hemorrhage [PDF]

Journal of Stroke, 2022
Background and Purpose Cerebral venous flow alterations potentially contribute to age-related white matter changes, but their role in small vessel disease has not been investigated. Methods This study included 297 patients with hypertensive intracerebral
Hsin-Hsi Tsai, Bo-Ching Lee, Ya-Fang Chen, Jiann-Shing Jeng, Li-Kai Tsai   +4 more
doaj   +1 more source

增龄相关性脑小血管病谱系的病理基础及其影像学特点 Pathological Basis and Imaging Characteristics of Spectrum of Age-related Cerebral Small Vessel Diseases

Zhongguo cuzhong zazhi, 2019
增龄相关性脑小血管病谱系（spectrum o f a ge-related cerebral small vessel diseases， ArCSVDS）是指随着年龄的增长，脑小动脉、微动脉、毛细血管、微静脉、小静脉出现老化的一组脑 小血管病（cerebral small vessel disease，CSVD），包括深穿支动脉病（deep perforating arteriopathy，DPA） 和β淀粉样蛋白（β-amyloid，Aβ）有关的脑淀粉样血管病（cerebral amyloid ...
陆正齐，宋康宇
doaj   +1 more source

A novel COL4A1 variant associated with recurrent epistaxis and glioblastoma

Human Genome Variation, 2021
COL4A1-related disorders are characterized by a higher incidence of cerebral hemorrhage than other hereditary cerebral small vessel diseases. Accumulating data have shown broad phenotypic variations, and extracerebral hemorrhages have been linked to ...
Kohei Muto, Ryosuke Miyamoto, Yuka Terasawa, Yoshimitsu Shimatani, Keijiro Hara, Takumi Kakimoto, Tatsuya Fukumoto, Yusuke Osaki, Koji Fujita, Masafumi Harada, Hisanori Uehara, Yasushi Takagi, Yuishin Izumi   +12 more
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Cerebral Small Vessel Disease and Alzheimer's Disease: A Review

Frontiers in Neurology, 2020
Alzheimer's disease (AD) is the most common cause of dementia. Despite this, clear pathophysiology for AD has not been confirmed, and effective treatments are still not available.
Hae Won Kim, Jeongho Hong, Jae Cheon Jeon   +2 more
doaj   +1 more source