A Vessel for Change: Endothelial Dysfunction in Cerebral Small Vessel Disease [PDF]
The blood vessels of the brain are lined with endothelial cells and it has been long known that these help to regulate blood flow to the brain. However, there is increasing evidence that these cells also interact with the surrounding brain tissue. These interactions change when the endothelial cells become dysfunctional and have an impact in diseases ...
Quick, S +3 more
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How diet affects Alzheimer's disease and small vessel disease
Introduction The number of people with memory disorders is increasing worldwide. Changing certain lifestyle factors can prevent the development of those disorders. Diet is a central factor that can be changed.
Juha Lempiäinen
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Progress of deep learning in cerebral small vessel disease imaging markers
With the rapid development of artificial intelligence (AI) technology, especially the application of deep learning (DL), the detection and quantitative evaluation of typical imaging markers of small cerebral vascular disease (CSVD) has been accelerated ...
BAI Xue⁃dong +2 more
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Cerebral small vessel disease: a bibliometric analysis
Abstract Background Cerebral small vessel disease is a common neurological disease, and its incidence is increasing year by year worldwide. In recent years, research on cerebral small vessel disease has gained more and more attention. Our research aims to visualize publications to identify the hotspots and frontiers of cerebral small vessel ...
Ma, Wei +5 more
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Large-vessel correlates of cerebral small-vessel disease [PDF]
Our aim was to investigate the relationship of carotid structure and function with MRI markers of cerebral ischemic small-vessel disease.The study comprised 1,800 participants (aged 72.5 ± 4.1 years, 59.4% women) from the 3C-Dijon Study, a population-based, prospective cohort study, who had undergone quantitative brain MRI and carotid ultrasound.
Brisset, Marion +10 more
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Gait in Elderly With Cerebral Small Vessel Disease [PDF]
Background and Purpose— Gait disorders are common in the elderly and are related to loss of functional independence and death. White matter lesions (WMLs) may be related, but only a minority of individuals with WMLs has gait disorders.
de Laat, K.F. +8 more
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Mechanisms of Cognitive Impairment in Cerebral Small Vessel Disease: Multimodal MRI Results from the St George's Cognition and Neuroimaging in Stroke (SCANS) Study. [PDF]
Cerebral small vessel disease (SVD) is a common cause of vascular cognitive impairment. A number of disease features can be assessed on MRI including lacunar infarcts, T2 lesion volume, brain atrophy, and cerebral microbleeds.
Lawrence, AJ +40 more
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Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate [PDF]
Cerebral small vessel disease is a leading cause of stroke and a major contributor to cognitive decline and dementia, but our understanding of specific genes underlying the cause of sporadic cerebral small vessel disease is limited.
Debette, Stephanie +99 more
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Advanced MRI in cerebral small vessel disease [PDF]
Cerebral small vessel disease (cSVD) is a major cause of stroke and dementia. This review summarizes recent developments in advanced neuroimaging of cSVD with a focus on clinical and research applications. In the first section, we highlight how advanced structural imaging techniques, including diffusion magnetic resonance imaging (MRI), enable improved
Hilde van den Brink +2 more
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Structural network efficiency is associated with cognitive impairment in small-vessel disease. [PDF]
To characterize brain network connectivity impairment in cerebral small-vessel disease (SVD) and its relationship with MRI disease markers and cognitive impairment.METHODS: A cross-sectional design applied graph-based efficiency analysis to deterministic
Lawrence, AJ +14 more
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