Results 51 to 60 of about 98,114 (150)

Effects of Carotid Artery Stiffness on Cerebral Small‐Vessel Disease and Cognition

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Carotid artery stiffness is associated with cognitive impairment and dementia, but the underlying mechanisms remain unknown. We examined the associations of carotid artery stiffness with cerebral small‐vessel disease markers, cognition, and ...
Caroline Robert, Lieng‐Hsi Ling, Eugene S. J. Tan, Bibek Gyanwali, Narayanaswamy Venketasubramanian, Shir Lynn Lim, Lingli Gong, Josephine Lunaria Berboso, Arthur Mark Richards, Christopher Chen, Saima Hilal   +10 more
doaj   +1 more source

Asymmetric Dimethylarginine in Cerebral Small Vessel Disease [PDF]

Stroke, 2007
Background and Purpose— Endothelial dysfunction may play a causal role in cerebral small vessel disease (SVD). Asymmetric dimethylarginine (ADMA), a circulating endogenous inhibitor of nitric oxide, has been implicated in endothelial dysfunction, particularly in hyperhomocystinemia, a known risk ...
Usman, Khan, Ahamad, Hassan, Patrick, Vallance, Hugh S, Markus   +3 more
openaire   +2 more sources

Dawson's Fingers in Cerebral Small Vessel Disease [PDF]

Frontiers in Neurology, 2020
To explore Dawson's fingers in cerebral small vessel disease (CSVD) and factors related to the development of Dawson's finger, we collected and analyzed clinical data of 65 patients with CSVD. We found a venous abnormality feature called Dawson's fingers around the ventricles in magnetic resonance images (MRIs) of 20 out of 65 patients with CSVD (30. 8%
Aowei Lv, Zaiqiang Zhang, Ying Fu, Yaping Yan, Li Yang, Wenli Zhu   +5 more
openaire   +3 more sources

Imaging-validated correlates and implications of the pathophysiologic mechanisms of ageing-related cerebral large artery and small vessel diseases: a systematic review and meta-analysis

Behavioral and Brain Functions
Background Cerebral large artery and small vessel diseases are considered substrates of neurological disorders. We explored how the mechanisms of neurovascular uncoupling, dysfunctional blood–brain-barrier (BBB), compromised glymphatic pathway, and ...
Joseph A. Ackah, Xuelong Li, Huixing Zeng, Xiangyan Chen   +3 more
doaj   +1 more source

Progressive Cerebral Small Vessel Disease Caused by an Autoimmune Response to Intravesical Bacille-Calmette-Guérin Treatment

Frontiers in Neurology, 2020
Systemic BCGitis and autoimmune diseases are possible adverse events of intravesical Bacille Calmette-Guérin-(BCG)-instillations in the treatment of urothelioma cancer.
Anouck Becker, Iris Quasar Grunwald, Iris Quasar Grunwald, Marcus M. Unger, Stefanie Behnke, Joerg Spiegel, Umut Yilmaz, Silke Walter, Silke Walter, Klaus Faßbender   +9 more
doaj   +1 more source

Neuroimaging of Cerebral Small Vessel Disease

Brain Pathology, 2014
Neuroimaging of cerebral small vessel vascular disease is often nonspecific and the diagnosis is challenging; clinical and family history is pivotal in interpreting neuroimaging findings. Hereditary small vessel diseases have recently gained significant interest, and MRI is a sensitive tool to detect white matter abnormality.
openaire   +3 more sources

Genetics of common cerebral small vessel disease

Nature Reviews Neurology, 2022
Cerebral small vessel disease (cSVD) is a leading cause of ischaemic and haemorrhagic stroke and a major contributor to dementia. Covert cSVD, which is detectable with brain MRI but does not manifest as clinical stroke, is highly prevalent in the general population, particularly with increasing age.
Bordes, Constance, Sargurupremraj, Muralidharan, Mishra, Aniket, Debette, Stephanie   +3 more
openaire   +3 more sources

Advances in the correlation between cerebral small vessel disease and sleep disorders

Chinese Journal of Contemporary Neurology and Neurosurgery, 2021
In clinical practice, cerebral small vessel disease (CSVD) and sleep disorders are two common diseases in the elderly, the correlation between the two is not clear yet.
ZHAN Fei⁃xia, CHEN Xiao⁃han, ZHAO Yu⁃cheng, MA Yue⁃jin, ZHUANG Jian⁃hua, YIN You   +5 more
doaj   +1 more source

Hypercholesterolemia induced cerebral small vessel disease

PLOS ONE, 2017
While hypercholesterolemia plays a causative role for the development of ischemic stroke in large vessels, its significance for cerebral small vessel disease (CSVD) remains unclear. We thus aimed to understand the detailed relationship between hypercholesterolemia and CSVD using the well described Ldlr-/- mouse model.We used Ldlr-/- mice (n = 16) and ...
Peter Kraft, Michael K. Schuhmann, Cornelia Garz, Solveig Jandke, Daniela Urlaub, Stine Mencl, Alma Zernecke, Hans-Jochen Heinze, Roxana O. Carare, Christoph Kleinschnitz, Stefanie Schreiber   +10 more
openaire   +5 more sources

Diabetic cerebral microvascular disorder: from key pathologies to targeted interventions

Annals of Medicine
Background Diabetes mellitus, a highly prevalent metabolic disorder worldwide, poses a severe threat to patient health primarily through its debilitating vascular complications.
Qihan Zhang, Jia Liu, Xunming Ji
doaj   +1 more source