Results 61 to 70 of about 7,881,496 (248)

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Two cases of IgG4-related disease accompanied by many cerebral microbleeds and a review of the literature : can IgG4-related disease cause cerebral small vessel vasculitis/vasculopathy? [PDF]

, 2021
IgG4-related disease (IgG4-RD) is a condition of unknown cause, which involves marked tissue infiltration by IgG4-positive plasma cells into various organs throughout the body. Histopathological examinations based on biopsy examinations are essential for
Ukai, Katsuyuki
core   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate [PDF]

, 2022
Cerebral small vessel disease is a leading cause of stroke and a major contributor to cognitive decline and dementia, but our understanding of specific genes underlying the cause of sporadic cerebral small vessel disease is limited.
Debette, Stephanie, Psaty, Bruce M., Weiss, Stefan, Gudnason, Vilmundur, Rotter, Jerome I, Yang, Qiong, Tzourio, Christophe, Fornage, Myriam, Bülow, Robin, Jian, Xueqiu, Vojinovic, Dina, Duplaà, Cécile, Kardia, Sharon LR, Gottesman, Rebecca F., Vernooij, Meike W, SMITH, Jennifer A., Boerwinkle, Erik, Kardia, Sharon L R, Ikram, M. Arfan, Grabe, Hans J, Hofer, Edith, Bis, Joshua C, DeCarli, Charles S, MUNOZ MANIEGA, Susana, Lathrop, Mark, ROTTER, Jerome I., Harris, Sarah E, Gottesman, Rebecca F, Schmidt, Helena, Gampawar, Piyush G., KNOPMAN, David S., Lopez, Oscar L, Beiser, Alexa S., Zilhão, Nuno R, van der Auwera-Palitschka, Sandra, Bastin, Mark E., Luciano, Michelle, Bastin, Mark E, Zhao, Wei, Deary, Ian J, Psaty, Bruce M, Matthews, Paul M, Joutel, Anne, Li, Shuo, Launer, Lenore J, Decarli, Charles S., Ihara, Masafumi, Schmidt, Reinhold, Kardia, Sharon L.R., Adams, Hieab H H, Wittfeld, Katharina, Dufouil, Carole, Gampawar, Piyush G, Adams, Hieab H.H., Lopez, Oscar L., Muñoz Maniega, Susana; id_orcid, Valdés Hernández, Maria, Mosley, Thomas H., Beiser, Alexa S, Kacprowski, Tim, Longstreth, William T., Morris, Zoe, Satizabal, Claudia L, Bartz, Traci M, Völker, Uwe, Zhu, Yicheng, Longstreth, William T, Vernooij, Meike W., Sargurupremraj, Muralidharan, Suzuki, Hideaki, Adams, Hieab HH, Vernooij, Meike W.; id_orcid, Grabe, Hans J., Wardlaw, Joanna M., Knopman, David S, Mosley, Thomas H, Deary, Ian J., Maniega, Susana Muñoz, Couffinhal, Thierry, Harris, Sarah E., ZILHAO, Nuno R., Amouyel, Philippe, Mazoyer, Bernard, Mishra, Aniket, Yu, Miao, van Duijn, Cornelia M, Bis, Joshua C., Ikram, M Arfan, Bartz, Traci M., Seshadri, Sudha, Launer, Lenore J., Satizabal, Claudia L., Wardlaw, Joanna M, Matthews, Paul M., Teumer, Alexander, Smith, Jennifer A, Van Duijn, Cornelia M., Tournier-Lasserve, Elizabeth, Hernández, Maria Valdés, Soumare, Aicha   +99 more
core   +2 more sources

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes, Leonardo Cruz‐Criollo, Eric Kontowicz, Marta Olivé‐Gadea, Francesco Diana, Johannes Kaesmacher, Adnan Mujanovic, Serdar Geyik, Songul Senadim, Amedeo Cervo, Andrea Salcuni, Mariangela Piano, Manuel Moreu, Alfonso López‐Frías, Ameer E. Hassan, Samantha Miller, Elena Zapata‐Arriaza, Asier de Albóniga‐Chindurza, Mauro Bergui, Stefano Molinaro, João André Sousa, Fábio Gomes, João Sargento‐Freitas, Andrea Alexandre, Alessandro Pedicelli, Jeremy Hofmeister, Paolo Machi, Luca Scarcia, Erwah Kalsoum, Jose Amorim, Torcato Meira, Leonardo Renieri, Francesco Capasso, Daniele Romano, Eduardo Bárcena‐Ruiz, David Seoane, Mohamad Abdalkader, Piers Klein, Thanh N. Nguyen, Catarina Perry da Câmara, Anderson Brito, Nashwa Abdelhakim, Isabel Fragata, Dileep R. Yavagal, Jude H. Charles, Jose Rodriguez Castro, Pedro Vega, Atilla Özcan Özdemir, Zehra Uysal Kocabaş, Stanislas Smajda, Sadiq Al Salman, Jane Khalife, Tudor G. Jovin, Francesco Biraschi, Francesca Richetti, Pedro Castro, Luis Albuquerque, Adnan Siddiqui, Vinay Jaikumar, Pedro Navia, Nikolaos Ntoulias, Marios Psychogios, Mariano Velo, Joaquín Zamarro, Gonzalo de Paco, Yazan Ashouri, Mohammad AlMajali, Juan F. Arenillas, Alicia Sierra, Michele Romoli, João Pedro Marto, Shadi Yaghi, Marc Ribo, Alejandro Tomasello, Manuel Requena, Santiago Ortega‐Gutierrez   +75 more
wiley   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Hereditary cerebral small vessel diseases: A review.

, 2012
Cerebral microangiopathies are responsible of a great number of strokes. In the recent years advances in molecular genetics identified several monogenic conditions involving cerebral small vessels and predisposing to ischemic and/or hemorrhagic stroke ...
FEDERICO, ANTONIO, Di Palma C, DI DONATO, ILARIA, Taglia I, DOTTI, MARIA, BIANCHI, SILVIA   +5 more
core   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source