Results 61 to 70 of about 8,233,957 (244)

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Hereditary cerebral small vessel disease and stroke

, 2017
Cerebral small vessel disease is considered hereditary in about 5% of patients and is characterized by lacunar infarcts and white matter hyperintensities on MRI.
Hansen, Christine Krarup, Christian Baastrup Søndergaard, Jørgen Erik Nielsen, Nielsen, Jørgen Erik, Christensen, Hanne, Søndergaard, Christian Baastrup, Christine Krarup Hansen, Hanne Christensen   +7 more
core   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Immune cells in cerebral small vessel disease: Emerging roles and potential targeting therapies

Neural Regeneration Research
Cerebral small vessel disease is an age-related condition that severely affects the quality of life of older adults; however, there are currently no definitive treatments or preventive measures.
Yating Zhan, Yiqin Wang, Meiling Bai, Juan Feng, Jiayi Wei, Jue Wang   +5 more
doaj   +1 more source

MRI features of cerebral small vessel disease [PDF]

, 2019
Cerebral small vessel disease affects brain vessels with the smallest caliber - small arteries, arterioles, venules, capillaries. There is strong association with cognitive impairment, dementia, psychiatric conditions, gait disturbances. The main markers
Balev, Boyan; Medical University of Varna, Kalchev, Emilian; Medical University of Varna, Georgiev, Radoslav; Medical University of Varna, Boyan Balev, Radoslav Georgiev, Emilian Kalchev   +5 more
core   +5 more sources

Copine‐4 Paraneoplastic Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang, Amy Ml Quek, Clement Yong, Amir Adeli, Gabrielle N. Conway, Connie E. Lesnick, Diana Anissian, Divyanshu Dubey, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael Gilligan, Andrew McKeon   +12 more
wiley   +1 more source

Diabetic cerebral microvascular disorder: from key pathologies to targeted interventions

Annals of Medicine
Background Diabetes mellitus, a highly prevalent metabolic disorder worldwide, poses a severe threat to patient health primarily through its debilitating vascular complications.
Qihan Zhang, Jia Liu, Xunming Ji
doaj   +1 more source

Association Between Endothelial Cell Stabilizing Medication and Small Vessel Disease Stroke: A Case-Control Study

Frontiers in Neurology, 2019
Increasing evidence suggests a role for endothelial cell (EC) dysfunction in pathogenesis of cerebral small vessel disease. Commonly used medications including certain antihypertensives and statins have EC-stabilizing effects.
Charlotte Elisabeth Becker, Charlotte Elisabeth Becker, Terence J. Quinn, Anna Williams   +3 more
doaj   +1 more source

Progress on diabetic cerebrovascular diseases [PDF]

, 2014
Diabetic cerebrovascular diseases are defined as cerebral vascular diseases induced by diabetes with sugar, fat and a series of nutrient substance metabolic disorders, resulting in intracranial large and small vessel diseases. About 20%-40% patients with
Zhang, Xiaoming, Zhou, Houguang, Lu, Jianfeng   +2 more
core   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source