Results 41 to 50 of about 7,881,496 (248)

Cerebral Small Vessel Diseases: From Vessel Alterations to Cortical Parenchymal Injury

, 2020
Cerebral Small Vessel Diseases (CSVD) represent a group of common age-related (but not clearly age-driven) microvascular brain pathologies, in which vessel injury leads to progressive accumulation of various small sized-tissue lesions (seen on ...

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Integration of Genome‐Wide Association Studies With Single‐Cell and Bulk Expression Quantitative Trait Locus to Identify Stroke Susceptibility Genes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Previous studies have integrated genome‐wide association studies with expression quantitative trait locus (eQTL) data from bulk tissues to identify stroke susceptibility genes. However, eQTL data exhibit high cell‐type specificity, and genetic
Yijie He, Tao Zhang, Ping Zhu, Shan Gao, Shiyang Wu, Fengzhen Liu, Yan Chen, Yingshui Yao, Guiyou Liu   +8 more
doaj   +1 more source

Asymptomatic Cerebral Small Vessel Disease: Insights from Population-Based Studies [PDF]

Journal of Stroke, 2019
Cerebral small vessel disease (CSVD) is a common group of neurological conditions that confer a significant burden of morbidity and mortality worldwide.
Alvin S. Das, Robert W. Regenhardt, Meike W. Vernooij, Deborah Blacker, Andreas Charidimou, Anand Viswanathan   +5 more
doaj   +1 more source

Cerebral small vessel disease: Cerebrospinal fluid aspects

, 2011
Introduction: The most common cerebral small vessel disease is the arteriolosclerotic variant located in the subcortical white and gray matter of the brain [1].
Bjerke, Maria,, Wallin, Anders,
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Neuroimaging Characteristics of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) in Korean Based on Jeju Cohort: A Pictorial Essay

Journal of the Korean Society of Radiology, 2023
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary small artery vasculopathy caused by mutations in the NOTCH3 gene on chromosome 19.
Yeh Rin Suh, Ho Kyu Lee, Kyeong Ho Jung, Jung Seok Lee, Jay Chol Choi   +4 more
doaj   +1 more source

Nonfocal Transient Neurological Attacks Are Associated With Cerebral Small Vessel Disease

, 2019
Background and Purpose-Nonfocal transient neurological attacks (TNAs), such as unsteadiness, bilateral weakness, or confusion, are associated with an increased risk of stroke and dementia.
Greving, Jacoba P., Kappelle, L. Jaap, Oudeman, Eline A., Bron, Esther E., Biessels, Geert Jan, Van den Berg-Vos, Renske M., de Bresser, Jeroen, van Oostenbrugge, Robert   +7 more
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Cerebral Small Vessel Disease

, 2020
Cerebral small vessel disease (CSVD) represents a cluster of various vascular disorders with different pathological backgrounds. The advanced vasculature net of cerebral vessels, including small arteries, capillaries, arterioles and venules, is usually ...
Marek Mazurek, Cezary Grochowski, Jakub Litak, Bartłomiej Kulesza, Paweł Szmygin, Joanna Litak, Piotr Kamieniak   +6 more
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Data from: Blood-brain barrier impairment and hypoperfusion are linked in cerebral small vessel disease [PDF]

, 2019
Objective: To investigate the link between BBB permeability and CBF and the relation with white matter hyperintensities (WMHs) in cerebral small vessel disease (cSVD).
Hoff, Erik I., van Oostenbrugge, Robert J., Staals, Julie, Wong, Sau May, Zhang, C. Eleana, Jansen, Jacobus F. A.; id_orcid, Jansen, Jacobus F. A., Backes, Walter H.   +7 more
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Targeting the brain’s glymphatic pathway: A novel therapeutic approach for cerebral small vessel disease

Neural Regeneration Research
Cerebral small vessel disease encompasses a group of neurological disorders characterized by injury to small blood vessels, often leading to stroke and dementia.
Yuhui Ma, Yan Han
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source