Results 61 to 70 of about 14,563 (162)
Plasma proteomics of cerebrovascular disease, cognitive decline, and clinical outcomes
Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.Abstract INTRODUCTION The plasma proteomic signatures underlying cerebrovascular disease (CeVD) remains poorly understood. METHODS A total of N = 2534 participants across two independent longitudinal Southeast‐Asian cohorts were included. We profiled 1441 baseline plasma proteins in a memory‐clinic cohort (N = 518), followed‐up for 4 years.
Ming Ann Sim +22 more
wiley +1 more source
Annals of Neurology, Volume 100, Issue 2, Page 345-360, August 2026.Objectives The interleukin (IL)‐1, IL‐6, and C‐reactive protein (CRP) pathway is central to the immune response after intracerebral hemorrhage (ICH). We tested for associations between hematoma and plasma cytokine concentrations and patient outcomes in Minimally Invasive Surgery Plus Rt‐PA for ICH Evacuation Phase III (MISTIE III) participants ...
Adrian R. Parry‐Jones +54 more
wiley +1 more source
Brain and Behavior, Volume 16, Issue 8, August 2026.ABSTRACT Introduction Pituitary neuroendocrine tumors (PitNETs) account for up to 15% of intracranial tumors. Patients commonly present with various emotional and cognitive impairments, including a high prevalence of anxiety and depression. Therefore, this study aimed to identify the latent subtypes of negative emotions in patients with PitNETs and ...
Lei Jin +7 more
wiley +1 more source
Brain‐Wide Mapping and Synaptic Localization of C1QL3 Using a Novel Epitope‐Tagged Knock‐In Mouse
Journal of Comparative Neurology, Volume 534, Issue 8, August 2026.C1QL3 is a secreted adhesion molecule that acts as a key regulator of synaptic structure and function. We generated and validated a novel epitope‐tagged knock‐in mouse line (C1ql32HA) in which two hemagglutinin (HA) epitopes were inserted near the N‐terminus of the endogenous C1QL3 protein.
William P. Armstrong IV +12 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.A trimodal machine‐learning framework integrating preoperative clinical variables, T1 morphometry, and glymphatic MRI metrics (DTI‐ALPS, choroid plexus volume) predicts symptom‐specific outcomes after bilateral STN‐DBS in PD. Trimodal models outperformed uni/bimodal approaches, achieving AUC 0.850–0.970 for motor, tremor, and gait improvement ...
Yining Wang +11 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.This study developed and externally validated the IVH topographical score (ITS) based on 11 IVH topographical patterns and clinical variables. The ITS classifies IVH patterns into four risk levels (0–3 points) and integrates GCS (3–8: 1 point), ICH volume (≥ 20 mL: 1 point), and hydrocephalus (4 points).
Ao Chen +5 more
wiley +1 more source
A 57-year-old male with diffuse astrocytoma in the lateral ventricle: case report. [PDF]
BMC NeurolWang J, Fan Y, Zhang W.
europepmc +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.Early postoperative inflammatory indices (SIRI, PLR, LMR) independently predict long‐term Neuro‐ICU stay after supratentorial brain tumor resection. By combining these biomarkers with clinical variables, the integrated prediction model enables reliable risk stratification and early clinical triage.
Biwu Wu +5 more
wiley +1 more source
When Stroke Leads to Hydrocephalus: A Case of Unilateral Ventricular Enlargement. [PDF]
CureusAyaluri VK, Reddy H, Mantri Vera Sai A.
europepmc +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.In our community‐based cohort, a lower baseline ALPS index is primarily associated with the progression of white matter microstructural disruption. Cortical atrophy occurs mainly in projection areas of affected white matter fibers. Therefore, the ALPS index represents a composite marker of perivascular dynamics and white matter microstructural ...
Chengqian Li +12 more
wiley +1 more source