Results 41 to 50 of about 330,546 (163)

18F‐FDG PET/CT in early phase of sporadic Creutzfeldt‐Jacob disease: A case report

open access: yesClinical Case Reports
Key Clinical Message Creutzfeldt–Jakob disease is a neurodegenerative disorder caused by brain accumulation of a misfolded form of the cellular prion protein, whose diagnosis is challenging, particularly in early stages, due to the variability and ...
Giovanni Boero   +6 more
doaj   +1 more source

The cerebellum in epilepsy

open access: yesEpilepsia, Volume 66, Issue 6, Page 1773-1792, June 2025.
Abstract The cerebellum, a subcortical structure, is traditionally linked to sensorimotor integration and coordination, although its role in cognition and affective behavior, as well as epilepsy, is increasingly recognized. Cerebellar dysfunction in patients with epilepsy can result from genetic disorders, antiseizure medications, seizures, and seizure‐
Christopher Elder   +4 more
wiley   +1 more source

Cerebro-rhino orbital mucormycosis: An update

open access: yesJournal of Infection and Public Health, 2012
Summary: Mucormycosis is an uncommon fungal infection which can lead to fulminant necrotizing infection under optimal host condition. Fungi have the ability to invade blood vessels and can affect different parts of the body.
Upender Wali   +2 more
doaj  

Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy

open access: yesMedComm, Volume 6, Issue 5, May 2025.
Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes   +4 more
wiley   +1 more source

Presymptomatic Biological, Structural, and Functional Diagnostic Biomarkers of Autism Spectrum Disorder

open access: yesJournal of Neurochemistry, Volume 169, Issue 5, May 2025.
Autism spectrum disorder (ASD) is diagnosed after behavioral symptoms emerge, highlighting the need for early biological markers, such as brain scans, genetic profiles, and biological samples from blood and urine tests, that could predict ASD before symptoms develop.
Bonnie M. Wang   +4 more
wiley   +1 more source

Reducing morbidity and mortality in high risk patients with statins

open access: yesVascular Health and Risk Management, 2009
Vibhuti Singh1, Prakash Deedwania21University of South Florida College of Medicine, and Suncoast Cardiovascular Center, St. Petersburg, Florida, USA; 2Cardiology Division, VACCHCS/UCSF, Fresno, CA, and UCSF School of Medicine, San Francisco, CA ...
Vibhuti Singh, Prakash Deedwania
doaj  

Cardiovascular Risk Factors Impact Brain Volume and White Matter Hyperintensities: A Multiethnic Cohort Study

open access: yesJournal of Neuroimaging, Volume 35, Issue 3, May/June 2025.
ABSTRACT Background and Purpose Brain atrophy and white matter hyperintensities (WMHs) are established markers of cerebrovascular disease, yet most evidence comes from older populations of predominantly European descent. We prospectively examined the relationship between cardiovascular risk factors and brain volumes and WMHs in middle‐aged participants
Esther M. C. Vriend   +8 more
wiley   +1 more source

Effects of Cerebellar Transcranial Magnetic Stimulation on the Motor Function of Patients With Stroke: A Systematic Review and Meta‐Analysis

open access: yesBrain and Behavior, Volume 15, Issue 4, April 2025.
cTMS can effectively improve the motor function of patients with stroke, with significant efficacy in balance and limb motor function. The therapeutic effect of cTMS was more pronounced when intervening in the subacute phase, and when the excitatory stimulation mode and moderate intensity (≤ 80% RMT) were used.
Yongxin Zhu   +7 more
wiley   +1 more source

Effects of Aging, Estimated Fitness, and Cerebrovascular Status on White Matter Microstructural Health

open access: yesHuman Brain Mapping, Volume 46, Issue 5, 01 April 2025.
White matter (WM) health declines with age and improves with estimated fitness. However, the effects of age and estimated fitness do not completely overlap spatially. Cerebrovascular health mediates the relationships of WM health with both age and estimated fitness. Males show steeper declines in WM health than females.
Grace M. Clements   +6 more
wiley   +1 more source

Atherogenic Index of Plasma (AIP) as a Long‐Term Prognostic Factor Following CABG: Unveiling Insights From a Large‐Scale Tertiary Center Registry Analysis

open access: yesHealth Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background and Aims The role of the atherogenic index of plasma (AIP) in predicting major adverse cerebro‐cardiovascular events (MACCE) after coronary artery bypass grafting (CABG) surgery has not been fully explored. The present study aims to investigate the prognostic value of AIP in predicting MACCE and its individual components following ...
Abolfazl Salari   +8 more
wiley   +1 more source

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