Results 41 to 50 of about 4,845 (107)

Multimodal Imaging Investigation of the Dentato‐Thalamo‐Cortical Pathway in Friedreich's Ataxia

Movement Disorders, EarlyView.
Abstract Background Friedreich's ataxia (FRDA) is a spinocerebellar neurodegenerative disorder. The dentato‐thalamo‐cortical (DTC) pathway, an important cerebellar output involved in motor control, plays a crucial role in the neural mechanisms underlying ataxia symptoms in FRDA.
Yinghua Jing, Imis Dogan, Ravi Dadsena, Jennifer Faber, Jörg B. Schulz, Kathrin Reetz, Sandro Romanzetti, on behalf of the FACROSS study group, Stella A. Lischewski, Kerstin Konrad, Miguel Pishnamaz, Maximillian Praster, Thomas Clavel, Vera Jankowski, Joachim Jankowski, Oliver Pabst, Katharina Marx‐Schütt, Nikolaus Marx, Julia Möllmann, Malte Jacobsen, Juergen Dukart, Simon Eickhoff, Ralf‐Dieter Hilgers   +22 more
wiley   +1 more source

Mini social cognition and emotional assessment: Diagnostic performance and neural correlates in behavioural‐variant frontotemporal dementia

Journal of Neuropsychology, EarlyView.
Abstract We aimed at validating the Mini Social Cognition and Emotional Assessment (Mini‐SEA) in a German cohort of mildly impaired behavioural‐variant frontotemporal dementia (bvFTD) patients and healthy controls. The Mini‐SEA comprises the Facial Emotion Recognition Test (FERT) and the Faux Pas Test (FPT) measuring Theory of Mind (ToM) abilities in ...
Cem Doğdu, Neeraj Upadhyay, Ingo Frommann, Luca Kleineidam, Andreas Johnen, Melina Stark, Sandra Roeske, Annika Spottke, Anna Gamez, Gabor C. Petzold, Louise Droste zu Senden, Julian Hellmann‐Regen, Stefan Hetzer, Klaus Fliessbach, Carolin Miklitz, Emrah Düzel, Falk Lüsebrink, Wenzel Glanz, Stefan Teipel, Ingo Kilimann, Josef Priller, Eike Jakob Spruth, Johannes Prudlo, David Mengel, Klaus Scheffler, Matthis Synofzik, Anja Schneider, Michael Wagner   +27 more
wiley   +1 more source

Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Their bioactive constituents act through antioxidant, anti‐inflammatory, and metabolic‐regulating mechanisms, validating their classification as functional foods. Evidence from clinical and biochemical studies largely supports these benefits, although some claims stem from preliminary or in vitro findings.
Nighat Raza, Alina Sadaf, Reeha Mushtaq, Mirza Abid Mehmood, Luqman Amrao, Fakhar Islam, Muhammad Afzaal, Mohd Asif Shah   +7 more
wiley   +1 more source

The Sense of Smell (SoS) Atlas: Its Creation and First Application to Investigate COVID‐19 Related Anosmia With a Comprehensive Quantitative MRI Protocol

Journal of Magnetic Resonance Imaging, Volume 63, Issue 2, Page 574-593, February 2026.
ABSTRACT Background The loss of smell (anosmia) has been noted in numerous diseases, including COVID‐19. Inflammatory and microstructural alterations are possible underlying mechanisms of anosmia in COVID‐19. However, no atlas exists to study olfaction and the associated tissue property changes.
Marta Gaviraghi, Eleonora Lupi, Elena Grosso, Andrea Fusari, Mattia Baiguera, Anita Monteverdi, Marco Battiston, Francesco Grussu, Baris Kanber, Ferran Prados Carrasco, Rebecca S. Samson, Janine Makaronidis, Marios C. Yiannakas, Michael S. Zandi, Rachel L. Batterham, Egidio D'Angelo, Fulvia Palesi, Claudia A. M. Gandini Wheeler‐Kingshott   +17 more
wiley   +1 more source

Decreased 24‐hour Parasympathetic Activity following Intracerebral Hemorrhage: A Key Factor Correlated with Adverse Perihematomal Edema and Poor Functional Outcomes

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
This study investigated associations between 24‐hour heart rate variability (HRV)‐assessed autonomic activity and perihematomal edema (PHE) development plus functional outcomes in 312 intracerebral hemorrhage (ICH) patients. Parasympathetic hypoactivity (low high‐frequency power) independently correlated with poor 3‐month outcomes (modified Rankin ...
Kaijiang Kang, Zeqiang Ji, Yunyi Hao, Jianwei Wu, Yani Zhang, Haiyan Li, Hui Lin, Yuhao Guo, Chuanying Wang, Yang Du, Guangshuo Li, Yongshi Yao, Yijun Lin, Zheng Liu, Jiexin Liu, Xingquan Zhao   +15 more
wiley   +1 more source

The Cerebellar Connectome Disruptions in Ischemic Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Ischemic stroke disrupts the brain's modular organization (based on the Yeo/Buckner template). In patients with basal ganglia ischemic stroke, inter‐module functional connectivity is altered, characterized by increased intra‐cerebellar connectivity, reduced connectivity between ipsilesional cerebral and cerebellar modules, and enhanced connectivity ...
Xiuqin Wang, Tongyue Li, Jinhui Wang, Yanhui Fu, Zhenqiang Ma, Xiaoyan Wu, Yiying Wang, Yufeng Zang, Yulin Song, Yating Lv   +9 more
wiley   +1 more source

Gamma-aminobutyric acid as an element of the mechanisms of cerebro-renal interactions

Počki
The presence of many common aspects in autoregulatory mechanisms and processes of ensuring the constancy of the internal environment determines the uniqueness of the cerebro-renal system.
N.D. Filipets, D.D. Іvanov, О.V. Gerush, О.О. Filipets, О.Н. Kmet, N.M. Fundiur, K.V. Slobodian   +6 more
doaj   +1 more source

Antidiabéticos orais. Como começar e combinar sem risco cardiovascular

Revista Portuguesa de Cardiologia, 2013
Resumo: A diabetes é, reconhecidamente, um importante factor de risco cardiovascular e a doença cárdio-cérebro vascular constitui a principal causa de mortalidade nas pessoas com diabetes.
Rui Duarte
doaj   +1 more source

Integration of omics data in the diagnosis and therapy of glioblastoma

Brain Pathology, Volume 36, Issue 1, January 2026.
Integration of omics data in the diagnosis and therapy of glioblastoma. Abstract Since the 2016 update of the WHO Classification of Tumors of the Central Nervous System, omics data have been officially integrated into the diagnostic process for glioblastoma, the most prevalent and aggressive primary malignant brain tumor in adults.
Constantin Möller, Melanie Schoof, Keith L. Ligon, Ulrich Schüller   +3 more
wiley   +1 more source

18F‐FDG PET/CT in early phase of sporadic Creutzfeldt‐Jacob disease: A case report

Clinical Case Reports
Key Clinical Message Creutzfeldt–Jakob disease is a neurodegenerative disorder caused by brain accumulation of a misfolded form of the cellular prion protein, whose diagnosis is challenging, particularly in early stages, due to the variability and ...
Giovanni Boero, Filippo Lauriero, Donato Fusillo, Rosa Calvello, Antonia Cianciulli, Maria Antonietta Panaro, Piergianni Moda   +6 more
doaj   +1 more source