ABSTRACT Background The loss of smell (anosmia) has been noted in numerous diseases, including COVID‐19. Inflammatory and microstructural alterations are possible underlying mechanisms of anosmia in COVID‐19. However, no atlas exists to study olfaction and the associated tissue property changes.
Marta Gaviraghi +17 more
wiley +1 more source
The Δ4-desaturation pathway for DHA biosynthesis is operative in the human species: Differences between normal controls and children with the Zellweger syndrome [PDF]
Background Docosahexaenoic acid (DHA, 22:6ω3) is a fundamental component of cell membranes, especially in the brain and retina. In the experimental animal, DHA deficiency leads to suboptimal neurological performance and visual deficiencies. Children with
Manuela Martinez +5 more
core +1 more source
This study investigated associations between 24‐hour heart rate variability (HRV)‐assessed autonomic activity and perihematomal edema (PHE) development plus functional outcomes in 312 intracerebral hemorrhage (ICH) patients. Parasympathetic hypoactivity (low high‐frequency power) independently correlated with poor 3‐month outcomes (modified Rankin ...
Kaijiang Kang +15 more
wiley +1 more source
Near Infrared Spectroscopic Monitoring During Cardiopulmonary Exercise Testing Detects Anaerobic Threshold [PDF]
Cardiopulmonary exercise testing (CPET) provides assessment of the integrative responses involving the pulmonary, cardiovascular, and skeletal muscle systems.
Danduran, Michael J. +4 more
core +1 more source
The Cerebellar Connectome Disruptions in Ischemic Stroke
Ischemic stroke disrupts the brain's modular organization (based on the Yeo/Buckner template). In patients with basal ganglia ischemic stroke, inter‐module functional connectivity is altered, characterized by increased intra‐cerebellar connectivity, reduced connectivity between ipsilesional cerebral and cerebellar modules, and enhanced connectivity ...
Xiuqin Wang +9 more
wiley +1 more source
Regulation of brain endothelial barrier function by microRNAs in health and neuroinflammation [PDF]
Brain endothelial cells constitute the major cellular element of the highly specialized blood–brain barrier (BBB) and thereby contribute to CNS homeostasis by restricting entry of circulating leukocytes and blood-borne molecules into the CNS.
Arie Reijerkerk +6 more
core +3 more sources
Integration of omics data in the diagnosis and therapy of glioblastoma
Integration of omics data in the diagnosis and therapy of glioblastoma. Abstract Since the 2016 update of the WHO Classification of Tumors of the Central Nervous System, omics data have been officially integrated into the diagnostic process for glioblastoma, the most prevalent and aggressive primary malignant brain tumor in adults.
Constantin Möller +3 more
wiley +1 more source
Estudio de la especificidad de vías de insulina/IGF-1 en los patrones de arborización y señalización mediante el uso de virus asociados a adenovirus [PDF]
Objetivo: Las vías de señalización de insulina y del factor de crecimiento insulínico tipo I(IGF-1) están involucradas en el control de la arborización dendrítica, señalización y crecimientocelular.
Ribes-Navarro, Alberto +1 more
core +1 more source
Editorial on Cerebral endothelial and glial cells are more than bricks in the Great Wall of the brain: insights into the way the blood-brain barrier actually works (celebrating the centenary of Goldman's experiments) [PDF]
Carta editorial a la revista Frontiers in cellular neuroscience sobre las células endoteliales cerebrales y gliales. Se analiza la manera en que la barrera sangre-cerebro realmente funciona.Editorial letter to Frontiers in cellular neuroscience on ...
Elena GarcÃa-MartÃn +4 more
core +2 more sources
La aterosclerosis es un proceso de origen multicausal y se acompaña de una gran variedad de manifestaciones clínicas y humorales. Son conocidos los factores de riesgo aterogénicos como dislipidemias, hipertensión arterial, diabetes mellitus, obesidad ...
Regino Piñeiro Lamas +2 more
doaj

