Results 51 to 60 of about 19,079 (162)

Estudio de la especificidad de vías de insulina/IGF-1 en los patrones de arborización y señalización mediante el uso de virus asociados a adenovirus [PDF]

open access: yes, 2018
Objetivo: Las vías de señalización de insulina y del factor de crecimiento insulínico tipo I(IGF-1) están involucradas en el control de la arborización dendrítica, señalización y crecimientocelular.
Ribes-Navarro, Alberto   +1 more
core   +1 more source

Brain banks in Latin America: Infrastructure for diagnosis, research, and scientific equity in Mexico and the Caribbean

open access: yesAlzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract The establishment of brain banks is a strategic initiative to advance research on neurodegenerative diseases in Latin America. This article highlights the development, operations, and multidisciplinary framework of the National Dementia BioBank in Mexico and the National Brain Bank in the Dominican Republic. Both centers focus on the molecular
Nabil Itzi Luna‐Viramontes   +12 more
wiley   +1 more source

Cerebral blood flow autoregulation is impaired in schizophrenia [PDF]

open access: yes, 2017
Patients with schizophrenia have a higher risk of cardiovascular diseases and higher mortality from them than does the general population; however, the underlying mechanism remains unclear.
al, et, Ku, Hsiao-Lun, Lane, Timothy
core  

Defining and Addressing the Current Unmet Medical Needs for the Frontline Treatment of Advanced Stage Aggressive Large B‐Cell Lymphoma: A Perspective From an Ad Hoc Panel of Italian Experts

open access: yesHematological Oncology, Volume 43, Issue 6, November 2025.
ABSTRACT Aggressive large B‐cell lymphomas (LBCL) include a range of disease types characterized by heterogenous histopathologic, molecular, and genetic features. In this review, we summarize the main standardized disease assessments, treatments and patient journey and we discuss some of the questions that we will face in interpreting and applying ...
Antonio Pinto   +8 more
wiley   +1 more source

Reducing morbidity and mortality in high risk patients with statins

open access: yesVascular Health and Risk Management, 2009
Vibhuti Singh1, Prakash Deedwania21University of South Florida College of Medicine, and Suncoast Cardiovascular Center, St. Petersburg, Florida, USA; 2Cardiology Division, VACCHCS/UCSF, Fresno, CA, and UCSF School of Medicine, San Francisco, CA ...
Vibhuti Singh, Prakash Deedwania
doaj  

Vascular disease and vascular risk factors in relation to motor features and cognition in early Parkinson's disease [PDF]

open access: yes, 2016
Funded by Parkinson's UK National Institute for Health Research (NIHR) DeNDRoN network NIHR Newcastle Biomedical Research Unit Newcastle University NIHR funded Biomedical Research Centre in CambridgePeer reviewedPublisher ...
Bajaj, Nin   +14 more
core   +5 more sources

Distinct Clinicopathological Features of HER2‐Negative, HER2‐Low, and HER2‐Overexpressing Urothelial Carcinoma in a Large Chinese Cohort

open access: yesCancer Medicine, Volume 14, Issue 19, October 2025.
ABSTRACT Purpose To investigate the expression patterns of Human Epidermal Growth Factor Receptor 2 (HER2) and their clinicopathological associations across the full spectrum (negative, low, and overexpression) in a large cohort of Chinese urothelial carcinoma (UC) patients.
Shanshan Wang   +8 more
wiley   +1 more source

Transcription‐coupled repair: tangled up in convoluted repair

open access: yesThe FEBS Journal, Volume 292, Issue 20, Page 5288-5323, October 2025.
In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher   +3 more
wiley   +1 more source

Moderate intermittent hypoxic conditioning to enhance vascular function and cardiorespiratory fitness in the elderly: A randomized controlled trial

open access: yesPhysiological Reports, Volume 13, Issue 19, October 2025.
Abstract Vascular aging involves reduced endothelial function, a key factor in cardiovascular diseases. Intermittent hypoxia may improve endothelial function and cardiorespiratory fitness (CRF), but its effects in elderly individuals, especially in the mid‐term, have not yet been studied.
Hugo Randy   +10 more
wiley   +1 more source

Exercise therapy in adults with serious mental illness: a systematic review and meta-analysis [PDF]

open access: yes, 2014
Background: Individuals with serious mental illness are at a higher risk of physical ill health. Mortality rates are at least twice those of the general population with higher levels of cardiovascular disease, metabolic disease, diabetes, and respiratory
Geddes, John   +3 more
core   +2 more sources

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