Results 31 to 40 of about 3,459 (111)
Reducing morbidity and mortality in high risk patients with statins
Vascular Health and Risk Management, 2009 Vibhuti Singh1, Prakash Deedwania21University of South Florida College of Medicine, and Suncoast Cardiovascular Center, St. Petersburg, Florida, USA; 2Cardiology Division, VACCHCS/UCSF, Fresno, CA, and UCSF School of Medicine, San Francisco, CA ...
Vibhuti Singh, Prakash Deedwania
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The Cerebellar Connectome Disruptions in Ischemic Stroke
CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.Ischemic stroke disrupts the brain's modular organization (based on the Yeo/Buckner template). In patients with basal ganglia ischemic stroke, inter‐module functional connectivity is altered, characterized by increased intra‐cerebellar connectivity, reduced connectivity between ipsilesional cerebral and cerebellar modules, and enhanced connectivity ...
Xiuqin Wang +9 more
wiley +1 more source
Lateralization of the sgACC‐Based Neural Network in Treatment‐Resistant Depression
Depression and Anxiety, Volume 2026, Issue 1, 2026.Background While the left subgenual anterior cingulate cortex (sgACC) is a validated target for treating major depressive disorder (MDD) (e.g., with rTMS), the therapeutic relevance of the right sgACC is unknown. Given emerging evidence that treatment‐resistant depression (TRD) and non‐TRD (nTRD) may involve distinct neural circuits, a more precise ...
Xinyu Zhao +11 more
wiley +1 more source
Journal of Nucleic Acids, Volume 2026, Issue 1, 2026.Autism spectrum disorder is a complex neurological and developmental disorder that is characterized by altered brain structures and interconnectivity, which results in a vast array of psychosocial and physiological irregularities. This is due to the complex genetic topography of autism and to the intersectionality of genetic and environmental factors ...
Rachel A. Hellmann Whitaker +9 more
wiley +1 more source
Therapeutic potential of stem cells in pediatric neurology: Insights from clinical trials
Neuroprotection, Volume 3, Issue 4, Page 303-321, December 2025.Key characteristics of stem cells. Stem cells are essential in therapy due to their ability to self‐renew, ensuring a continuous supply of cells. They can derive from various sources, primarily embryonic tissue, and adult organs such as bone marrow and adipose tissue.
Daniel Bou Najm, Saada Alame
wiley +1 more source
Journal of Neurochemistry, Volume 169, Issue 12, December 2025.Elevated homocysteine results from genetic variants, impaired one‐carbon metabolism, nutritional deficiencies, and metabolic disorders. Hyperhomocysteinemia drives oxidative stress, inflammation, excitotoxicity, and epigenetic disruption, affecting multiple organs and systems.
Osmar Vieira Ramires Júnior +5 more
wiley +1 more source
残余代谢危险因素与青年卒中 Residual Metabolic Risk Factors and Stroke in Young Adults
Zhongguo cuzhong zazhi青年卒中一般指在18～50岁年龄段内发生的卒中，其发病率上升给我国带来了日益增加的社会经济负担。在探讨青年卒中的代谢危险因素时，除了传统的高血压、糖代谢异常、脂代谢异常和肥胖外，残余代谢危险因素亦不容忽视。本文重点关注了炎症、高同型半胱氨酸血症、高尿酸血症和肠道微生物群代谢产物这4种残余代谢危险因素对青年卒中的影响。炎症在青年卒中中的作用显著，与心源性脑栓塞这一重要病因的发生发展密切相关。高同型半胱氨酸血症通过影响血管内皮和凝血功能促进血栓形成，是有望预测卒中风险及预后的重要指标 ...
钱宇彤1，2，张书凡1，2，韩振翔3，吴维诚4，韩翔1，2 (QIAN Yutong1,2, ZHANG Shufan1,2, HAN Zhenxiang3, WU Weicheng4, HAN Xiang1,2 )
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Journal of Sleep Research, Volume 34, Issue 6, December 2025.ABSTRACT The bidirectional interaction between sleep and epilepsy is well known. In particular, it has been established that sleep apnea can worsen epilepsy, whereas sleep apnea (SA) treatment has a beneficial effect on seizure control. However, the exact mechanisms whereby SA promotes epileptic seizures are unknown.
Christian M. Horvath +4 more
wiley +1 more source
Preventive cytoprotection in social diseases
Терапевтический архив, 2015 Among many cytoprotective drugs, only a few of them that have a targeted metabolic effect include agents that partially inhibit oxidation of free fatty acids, the so-called p-FOX inhibitors (partial fatty acid oxidation inhibitors). Aim.
A S Skotnikov +4 more
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Revista Cubana de Investigaciones Biomédicas, 2012 La aterosclerosis es un proceso de origen multicausal y se acompaña de una gran variedad de manifestaciones clínicas y humorales. Son conocidos los factores de riesgo aterogénicos como dislipidemias, hipertensión arterial, diabetes mellitus, obesidad ...
Regino Piñeiro Lamas +2 more
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