Results 21 to 30 of about 3,459 (111)

Airway Involvement in Conradi–Hünermann–Happle Syndrome: A Novel Clinical Manifestation

The Laryngoscope, EarlyView.
We report the first documented case of airway involvement in Conradi–Hünermann–Happle syndrome (CDPX2), an X‐linked dominant form of chondrodysplasia punctata caused by pathogenic variants in EBP. A 2‐month‐old female with genetically confirmed CDPX2 developed severe subglottic stenosis and persistent respiratory distress requiring CPAP; cross ...
Enrique G. Villarreal, Jackie Chiang, Evan J. Propst, Nikolaus E. Wolter   +3 more
wiley   +1 more source

Antidiabéticos orais. Como começar e combinar sem risco cardiovascular

Revista Portuguesa de Cardiologia, 2013
Resumo: A diabetes é, reconhecidamente, um importante factor de risco cardiovascular e a doença cárdio-cérebro vascular constitui a principal causa de mortalidade nas pessoas com diabetes.
Rui Duarte
doaj   +1 more source

Molecular Profiling of Genes Associated With Methylphenidate Pathway Therapy and Discovery of New Variants in Amazonian Amerindian Populations

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 4, Page 291-299, June 2026.
ABSTRACT In Attention Deficit Hyperactivity Disorder (ADHD), methylphenidate is one of the most widely used drugs, in which patient response significantly impacts prognosis. This study aimed to characterize the molecular profile of 10 genes associated with methylphenidate therapy.
Aline Pasquini Santos, Tatiane Carinta de Souza, Kaio Evandro Cardoso Aguiar, Ana Caroline Alves da Costa, Natasha Monte, Juliana Carla Gomes Rodrigues, Giovanna Gilioli da Costa Nunes, Rita de Cássia Calderaro Coelho, Ândrea Ribeiro‐dos‐Santos, André Maurício Ribeiro dos Santos, Sandro José de Souza, Sidney Emanuel Batista dos Santos, Rommel Mario Rodriguez Burbano, Marianne Rodrigues Fernandes, Ney Pereira Carneiro dos Santos   +14 more
wiley   +1 more source

Hair Cortisol Concentrations in Children: A Longitudinal Analysis Across Childhood

Developmental Psychobiology, Volume 68, Issue 3, May 2026.
ABSTRACT Hair cortisol concentration (HCC) reflects long‐term cortisol exposure and is commonly used as a biomarker of hypothalamic–pituitary–adrenal axis activity. Although increasingly applied in pediatric populations, developmental changes in HCC and potential sex differences remain unclear.
Miguel Ángel Baos‐González, Javier De Echarri‐Lorente, María Ángeles García‐León, Raquel González‐Pérez, María Isabel Peralta‐Ramírez   +4 more
wiley   +1 more source

The Association of Periodontitis With Cardiovascular Disease Parameters: A Synthesis of Systematic Reviews

International Journal of Dental Hygiene, Volume 24, Issue 2, Page 278-306, May 2026.
ABSTRACT Focused Question What is the association of periodontal disease (PerioD) and cardiovascular diseases (CVD/CVE) as reported in existing systematic reviews (SRs)? Methods MEDLINE‐PubMed and Cochrane‐CENTRAL databases were searched. Papers that primarily evaluate cardiovascular parameters of CVD and CVE in PerioD patients compared to non‐PerioD ...
Max G. P. Schoenmakers, Lotte P. M. Weijdijk, Eveline J. S. Willems, Fridus (G. A.) van der Weijden, Dagmar Else Slot   +4 more
wiley   +1 more source

Regional cerebellar structural deficits distinguish psychostimulant‐free ADHD youth with and without familial risk for bipolar I disorder: a cross‐sectional morphometric analysis

Journal of Child Psychology and Psychiatry, Volume 67, Issue 5, Page 766-776, May 2026.
Background Although attention‐deficit/hyperactivity disorder (ADHD) with familial risk for bipolar I disorder (BD) may represent a more severe illness conferring greater risk for developing BD, associated neurostructural substrates remain poorly understood.
Biqiu Tang, L. Rodrigo Patino, Wenjing Zhang, Su Lui, Melissa P. DelBello, Robert K. McNamara   +5 more
wiley   +1 more source

The words community dwelling, Spanish‐preferring Mexican/Mexican American adults use to talk about Alzheimer's disease and genetic testing: Implications for education and outreach

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 2, April/June 2026.
Abstract INTRODUCTION Hispanic/Latino (H/L) adults are more likely than non‐Hispanic White individuals to have Alzheimer's disease (AD), yet fewer than one in five H/L adults has apolipoprotein E (APOE) Ɛ4, underscoring gaps in understanding genetic risk across H/L heritage groups.
Jamie C. Fong, Fatima I. Chavez, Karla Silos, Mirna L. Arroyo‐Miranda, Gabriela Castro Castro, Mark E. Kunik, Joshua M. Shulman, Luis D. Medina   +7 more
wiley   +1 more source

The landscape of dementia research, diagnosis, treatment, and care in Latin America

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Latin America is undergoing rapid population aging alongside a rising burden of dementia. While the region holds substantial potential for dementia risk reduction, challenges remain, such as delayed diagnoses, limited access to specialized care and biomarker testing, persistent stigma, and deep‐rooted structural inequities.
Claudia K. Suemoto, Nilton Custodio, Diego Aguilar, José A. Avila‐Funes, Sandra Baez, Pablo M. Bagnati, Lisa L. Barnes, Sonia M. D. Brucki, Ismael L. Calandri, Paulo Caramelli, Mario Cornejo‐Olivas, Carolina Delgado Derio, Sergio T. Ferreira, Adolfo M. García, Lea T. Grinberg, Agustin M. Ibanez, Rosario Isasi, Sylvia E. Josephy‐Hernández, Maria Lazo Porras, Jorge J. Llibre‐Guerra, Juan J. Llibre‐Rodriguez, Mychael V. Lourenco, B. Marcela Mar Meza, Joaquin Migeot, J. Jaime Miranda, Claudia Miranda‐Castillo, Catherine J. Mummery, José F. Parodi, Natalia Pozo Castro, Rosa María Salinas Contreras, Hernando Santamaría‐García, Andrea Slachevsky, Juliana N. Souza‐Talarico, Ezequiel I. Surace, Leonel T. Takada, Elena Tsoy, Martha Unaucho Pilalumbo, Eduardo R. Zimmer, Igor C Fontana, Simin Mahinrad, Heather M. Snyder, Maria C. Carrillo   +41 more
wiley   +1 more source

Clinical, biological and cytometric characteristics of two patients with a homozygous A91V PRF1 mutation

Clinical &Translational Immunology, Volume 15, Issue 3, 2026.
Familial haemophagocytic lymphohistiocytosis (FHL) is a rare, inherited granzyme–perforin system defect that predisposes individuals to haemophagocytic lymphohistiocytosis. This article presents two original case reports of FHL type 2, along with a comprehensive literature review. Together, these elements aim to enhance the current understanding of FHL
Nicolas Perrard, Claire Poggi, Sébastien Sanges, Bruno Lemarchant, Wadih Abou Chahlah, Louis Terriou, Stéphanie Delangue, Jacques Trauet, Myriam Labalette, Eric Hachulla, Despina Moshous, Guillaume Lefevre, David Launay   +12 more
wiley   +1 more source

Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Their bioactive constituents act through antioxidant, anti‐inflammatory, and metabolic‐regulating mechanisms, validating their classification as functional foods. Evidence from clinical and biochemical studies largely supports these benefits, although some claims stem from preliminary or in vitro findings.
Nighat Raza, Alina Sadaf, Reeha Mushtaq, Mirza Abid Mehmood, Luqman Amrao, Fakhar Islam, Muhammad Afzaal, Mohd Asif Shah   +7 more
wiley   +1 more source