Results 11 to 20 of about 3,459 (111)

Development and Validation of an Explainable Machine Learning Model for Identifying Hypertension Status in Patients With Obstructive Sleep Apnea. [PDF]

open access: yesJ Clin Hypertens (Greenwich)
ABSTRACT Obstructive sleep apnea (OSA) is an independent risk factor for hypertension (HTN) worldwide; however, OSA‐related HTN is frequently overlooked in clinical practice, partly because of the limitations of traditional clinical blood pressure measurements.
Wei F   +5 more
europepmc   +2 more sources

Fatty liver disease is not associated with increased mortality in the elderly: A prospective cohort study

open access: yesHepatology, EarlyView., 2022
Graphical abstract summarizing the study design, main results and key findings Abstract Background and Aims Fatty liver disease (FLD) has been associated with excess mortality. Screening for hepatic steatosis (HS) in patients with metabolic dysfunction is therefore recommended by several guidelines, despite a paucity of evidence on the clinical ...
Laurens A. van Kleef   +5 more
wiley   +1 more source

Relevance of Kidney‐Metabolic Multimorbidity Pattern to Metabolic Health and Mortality Among Elderly Inpatients in China [PDF]

open access: yesFood Sci Nutr
In this study, we established a large‐scale research database named as “Elderly Multimorbidity Database”. We introduced the novel identification of the “Kidney‐metabolic” multimorbidity pattern. The “Kidney‐metabolic” pattern, being the most prevalent in our study, significantly increases mortality risk, particularly in the oldest age groups.
Xu L   +6 more
europepmc   +2 more sources

Crossed cerebellar diaschisis in status epilepticus: A systematic review of the literature. [PDF]

open access: yesEpileptic Disord
Abstract Objective Crossed cerebellar diaschisis is a neuroimaging phenomenon observed in various neurological conditions, including status epilepticus. This systematic review aims to summarize the clinical and radiological characteristics of patients developing crossed cerebellar diaschisis following status epilepticus and to discuss potential ...
Tabaee Damavandi P   +6 more
europepmc   +2 more sources

牛磺酸在代谢性脑血管病中的潜在作用及其机制研究进展 Research Progress on the Potential Role of Taurine in Cerebro-Metabolic Disease and its Mechanism

open access: yesZhongguo cuzhong zazhi
代谢性脑血管病以代谢危险因素引起的脑血管损害为核心,其概念已被提出并处于早期探索阶段。代谢性脑血管病的防治重点在于控制代谢危险因素,目前临床用药策略仍是对各个代谢危险因素进行单独干预,因用药种类多和剂量大给患者带来很多困扰。因此,临床亟需一种具有多作用靶点、可协同作用的药物以减少代谢性脑血管病患者的用药负担并提高疗效。牛磺酸作为一种条件必需氨基酸,具有调节糖脂代谢、调节渗透压、稳定细胞膜、抗氧化、抗衰老等多种生物学作用,对代谢性脑血管病治疗具有潜在临床价值。本文聚焦牛磺酸多效性 ...
温家琦1,2,庞江霞1,2,陈超1,2,姜长春1,2,郝喜娃1,2 (WEN Jiaqi1,2, PANG Jiangxia1,2, CHEN Chao1,2, JIANG Changchun1,2, HAO Xiwa1,2 )
doaj   +1 more source

代谢组学在代谢性脑血管病中的应用研究 Application of Metabolomics in Cerebro-Metabolic Disease

open access: yesZhongguo cuzhong zazhi
脑血管病是全球范围内导致人类死亡和残疾的主要原因,其中很高比例与代谢紊乱相关。代谢性脑血管病是指由传统代谢危险因素和残余代谢危险因素导致的脑血管损害,以血管结构受损及功能障碍为主要病理生理学表现,干预代谢危险因素可有效改善预后的一种临床综合征。代谢组学是采用高通量组学技术对所有代谢物进行鉴定和定量的手段,是未来研究代谢性脑血管病的重要抓手。本文总结了代谢组学、脂质组学在代谢性心脑血管疾病方面的研究,旨在为代谢性脑血管病的代谢组学研究开展及其临床防治提供参考。 Abstract ...
钟文华1,薛婧2,许杰1,2 ( ZHONG Wenhua1, XUE Jing2, XU Jie1,2 )
doaj   +1 more source

DELIRIUM PERIOPERATORIO

open access: yesRevista Médica Clínica Las Condes, 2017
RESUMEN: Debido al cambio demográfico de las últimas décadas, los sistemas de salud se han visto enfrentados a atender a pacientes cada vez de mayor edad.El Delirium Perioperatorio (DPO) es la más seria y más frecuente complicación cognitiva del paciente
Jimena Rodríguez, Dra.
doaj   +1 more source

代谢性脑血管病的“多系统对话”与“多学科共管” “Multi-System Dialogue” and “Multi-Disciplinary Co-Management” of Cerebro-Metabolic Disease

open access: yesZhongguo cuzhong zazhi
代谢性脑血管病是一个新近提出的概念,指由传统代谢危险因素和残余代谢危险因素引起的脑血管损害,通过干预代谢危险因素可有效改善其预后的一种临床综合征。代谢途径并非独立存在,脑、心脏、肝脏、肾脏和肠道等多个器官的各种代谢途径相互影响、共同作用、交织成网,构成了人体的代谢网络,而代谢网络的异常导致了代谢性脑血管病的发生。同时,代谢危险因素的存在可同时造成多个靶器官损害,且神经系统与心血管系统、内分泌系统、消化系统等可通过多种病理生理过程相互影响。因此 ...
许杰, 王拥军 XU Jie, WANG Yongjun
doaj   +1 more source

肥胖相关慢性炎症与代谢性脑血管病 Obesity-Related Chronic Inflammation and Cerebro-Metabolic Disease

open access: yesZhongguo cuzhong zazhi
脑血管病目前已成为全球第二大死亡原因,其发病风险主要归因于代谢紊乱。本文就肥胖相关慢性炎症与代谢性脑血管病的发病机制进行综述。肥胖状态下免疫细胞聚集、促炎因子分泌增加、血管内皮损伤等是代谢性脑血管病的重要致病机制。以炎症为治疗靶点的生活方式干预、药物免疫治疗及减重抗炎治疗等新型、有效的防治策略,有望为降低代谢性脑血管病的发病率,提高患者的生存率和生活质量提供参考依据。 Abstract: Cerebrovascular disease has become the second cause of ...
梁小雪, 郭黎 LIANG Xiaoxue, GUO Li
doaj   +1 more source

Clinical disorders in a post war British cohort reaching retirement: evidence from the First National Birth Cohort study.

open access: yesPLoS ONE, 2012
BackgroundThe medical needs of older people are growing because the proportion of the older population is increasing and disease boundaries are widening.
Mary B Pierce   +11 more
doaj   +1 more source

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