Results 11 to 20 of about 2,092 (196)
Treatment with Cerebrolysin Prolongs Lifespan in a Mouse Model of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy [PDF]
Advanced Biology, Volume 8, Issue 2, February 2024., 2023 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare familial neurological disorder caused by mutations in the NOTCH3 gene and characterized by migraine attacks, depressive episodes, lacunar ...
Biller, Janina +5 more
core +2 more sources
Clinical Case Reports, 2021 This clinical case is an example of a potential synergistic neuroprotective interaction of Cerebrolysin and high doses of aspirin. The case describes the significant recovery of neurological deficits in a patient with moderate ischemic stroke (NIHSS 12 ...
Alexander Borisevich +1 more
doaj +2 more sources
Effects of Cerebrolysin on Hippocampal Neuronal Death After Pilocarpine-Induced Seizure
Frontiers in Neuroscience, 2020 Epilepsy is one of the most common and severe brain diseases. The exact cause of epilepsy is unclear. Epilepsy often occurs following brain damage, such as traumatic brain injury (TBI) and ischemia.
Dong Hyeon Kang +14 more
doaj +1 more source
BMC Neurology, 2023 Background Cerebrolysin could mitigate reperfusion injury and hemorrhagic transformation (HT) in animal models of acute ischemic stroke. Methods This was a prospective, randomized, open-label, parallel-group with active control, multicenter pilot study ...
Dina R. Khasanova, Mikhail N. Kalinin
doaj +1 more source
The influence of neurotrophic factors treatment on stroke volume [PDF]
Romanian Journal of Neurology, 2013 Background. Cerebrolysin is a multimodal drug, with pleiotropic neuroprotective effects that simultaneously promotes neuroprotection while retaining the ability to influence neuroplasticity. Cerebrolysin is approved for the treatment of stroke, traumatic
Adina Dora Stan +7 more
doaj +1 more source
Cerebrolysin: spectrum of activity and research data
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018 The results of analysis of experimental and clinical studies have shown that Cerebrolysin application is safe and effective therapy for many neurological disorders ranging from stroke and ending Alzheimer’s disease.
N. D. Bukreeva, E. A. Rakityanskaya
doaj +1 more source
Pharmaceuticals, 2021 We performed a systematic search and meta-analysis of available literature to determine the safety profile of Cerebrolysin in acute ischemic stroke, filling existing safety information gaps and inconsistent results.
Stefan Strilciuc +6 more
doaj +1 more source
Medicinal Research Reviews, Volume 43, Issue 5, Page 1668-1700, September 2023., 2023 Abstract Neurotrophic factors (NTFs) are involved in the pathophysiology of neurological disorders such as dementia, stroke and traumatic brain injury (TBI), and constitute molecular targets of high interest for the therapy of these pathologies. In this review we provide an overview of current knowledge of the definition, discovery and mode of action ...
Konrad Rejdak +3 more
wiley +1 more source
Frontiers in Neuroscience, 2023 IntroductionTraumatic brain injury (TBI) is a major public health problem affecting millions worldwide. Despite significant advances in medical care, there are limited effective interventions for improving cognitive and functional outcomes in TBI ...
Olivia Verisezan Rosu +18 more
doaj +1 more source
Clinical Case Reports, Volume 10, Issue 11, November 2022., 2022 Abstract Severe traumatic brain injury (sTBI) is a major cause of death and disability worldwide, resulting in a significant individual and socioeconomic burden. Current treatment guidelines do not include any recommendations for neuroprotective or neuoregenerative drugs.
Helmut Trimmel +4 more
wiley +1 more source