Results 31 to 40 of about 2,092 (196)

Adult Hippocampal Neurogenesis in Alzheimer’s Disease: An Overview of Human and Animal Studies with Implications for Therapeutic Perspectives Aimed at Memory Recovery

open access: yesNeural Plasticity, Volume 2022, Issue 1, 2022., 2022
The mammalian hippocampal dentate gyrus is a niche for adult neurogenesis from neural stem cells. Newborn neurons integrate into existing neuronal networks, where they play a key role in hippocampal functions, including learning and memory. In the ageing brain, neurogenic capability progressively declines while in parallel increases the risk for ...
Stefano Farioli-Vecchioli   +3 more
wiley   +1 more source

CEREBROLYSIN FOR ACUTE ISCHEMIC STROKE

open access: yesAnnals of the Russian academy of medical sciences, 2013
Cerebrolysin is a mixture of low-molecular-weight peptides and amino acids derived from pigs' brain tissue, which has potential neuroprotective and neurotrophic properties. It is widely used in the treatment of acute ischaemic stroke in Russia, China, and other Asian and post-Soviet countries.To assess the benefits and risks of Cerebrolysin for ...
Ziganshina L., Abakumova T.
openaire   +6 more sources

Pharmacological management of immune and oxidative disturbances in patients with encephalopathy on the background of hypertension [PDF]

open access: yes, 2016
Inclusion of a comprehensive drug treatment of patients with discirculatory encephalopathy cerebrolysin combination with meksidol normalizes the concentration of C3 and C4 components of the complement system, IgG, malondialdehyde, catalase activity ...
Bistrova, N. A.   +2 more
core   +2 more sources

The Role of Cerebrolysin in Promoting Axonal Regeneration and Functional Recovery after Peripheral Nerve Injury: A Focus on Macrophage Activation [PDF]

open access: yesAdvanced Pharmaceutical Bulletin
Purpose: The research investigated the neuroprotective properties of Cerebrolysin regarding functional recovery, axonal regeneration, and macrophage polarization in a rat model of acute sciatic nerve damage.
Aida Karimian   +4 more
doaj   +1 more source

Effect of cerebrolysin on oxidative stress-induced apoptosis in an experimental rat model of myocardial ischemia [PDF]

open access: yes, 2016
Apoptosis plays a role in the process of tissue damage after myocardial infarction (MI). This study was designed to investigate the possible effect of cerebrolysin against apoptosis triggered by oxidative cell stress in myocardial ischemia induced by ...
Acikel   +97 more
core   +1 more source

Nanoparticle transport across the blood brain barrier [PDF]

open access: yes, 2016
: While the role of the blood-brain barrier (BBB) is increasingly recognized in the (development of treatments targeting neurodegenerative disorders, to date, few strategies exist that enable drug delivery of non-BBB crossing molecules directly to their ...
BELLETTI, Daniela   +6 more
core   +1 more source

Cerebrolysin in Patients with TBI: Systematic Review and Meta-Analysis

open access: yesBrain Sciences, 2023
TBI (traumatic brain injury) is one of the most common causes of deaths and failure to return to society according to the latest statistics. Cerebrolysin is a drug approved for use in patients diagnosed with TBI.
Konrad Jarosz   +4 more
doaj   +1 more source

Making Waves in the Brain: What Are Oscillations, and Why Modulating Them Makes Sense for Brain Injury. [PDF]

open access: yes, 2016
Traumatic brain injury (TBI) can result in persistent cognitive, behavioral and emotional deficits. However, the vast majority of patients are not chronically hospitalized; rather they have to manage their disabilities once they are discharged to home ...
Gurkoff, Gene G   +4 more
core   +1 more source

Efficacy of Cerebrolysin Treatment as an Add-On Therapy to Mechanical Thrombectomy in Patients With Acute Ischemic Stroke Due to Large Vessel Occlusion: Study Protocol for a Prospective, Open Label, Single-Center Study With 12 Months of Follow-Up

open access: yesFrontiers in Neurology, 2022
This study is designed to determine the efficacy of Cerebrolysin treatment as an add-on therapy to mechanical thrombectomy (MT) in reducing global disability in subjects with acute ischemic stroke (AIS). We have planned a single center, prospective, open-
Jacek Staszewski   +13 more
doaj   +1 more source

Clinical efficacy of long-term treatment in patients with vascular dementia

open access: yesБюллетень сибирской медицины, 2011
To study efficacy and safety of prolonged course of cerebrolysin therapy in vascular dementia, 48 patients, aged from 59—77 years, with mild and moderate dementia have been studied.
I. A. Suvorova
doaj   +1 more source

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