Evaluation of microbial bacterial and fungal diversity in cerebrospinal fluid shunt infection. [PDF]
PLoS ONE, 2014 Cerebrospinal fluid shunt infection can be recalcitrant. Recurrence is common despite appropriate therapy for the pathogens identified by culture. Improved diagnostic and therapeutic approaches are required, and culture-independent molecular approaches ...
Tamara D Simon +8 more
doaj +1 more source
Ganciclovir penetrates into the cerebrospinal fluid of an infant with congenital cytomegalovirus infection [PDF]
, 2015 Currently, there is no evidence whether ganciclovir, or its oral prodrug valganciclovir, penetrates into the cerebrospinal fluid of human infants treated for congenital cytomegalovirus infection.
Bizzarri, Bianca +6 more
core +2 more sources
Cerebrospinal fluid cytotoxicity in amyotrophic lateral sclerosis:a systematic review of in vitro studies [PDF]
, 2020 Various studies have suggested that a neurotoxic cerebrospinal fluid profile could be implicated in amyotrophic lateral sclerosis. Here, we systematically review the evidence for cerebrospinal fluid cytotoxicity in amyotrophic lateral sclerosis and ...
Chandran, Siddharthan +4 more
core +1 more source
A model for the oscillatory flow in the cerebral aqueduct [PDF]
J. Fluid Mech. vol. 899, R1, 1-12 (2020), 2022 This paper addresses the pulsating motion of cerebrospinal fluid in the aqueduct of Sylvius, a slender canal connecting the third and fourth ventricles of the brain. Specific attention is given to the relation between the instantaneous values of the flow rate and the interventricular pressure difference, needed in clinical applications to enable ...
arxiv +1 more source
Lombalgia progressiva secundária a coleção epidural de líquor: uma complicação rara da punção lombar em adolescentes [PDF]
, 2022 Lumbar puncture is commonly performed in Pediatrics. Common complications include headache and mild pain at the puncture site. Uncommon complications after the procedure, such as epidural cerebrospinal fluid collection, have rarely been described in ...
Carvalho, Leonor +3 more
core +1 more source
Abnormal expression of cerebrospinal fluid cation chloride cotransporters in patients with Rett Syndrome [PDF]
, 2013 Objective: Rett Syndrome is a progressive neurodevelopmental disorder caused mainly by mutations in the gene encoding methyl-CpG-binding protein 2. The relevance of MeCP2 for GABAergic function was previously documented in animal models. In these models,
Armstrong, Judith +11 more
core +4 more sources
Cerebrospinal fluid dynamics [PDF]
, 2021 The classical cerebrospinal fluid (CSF) circulation theory has been accepted as an established theory of CSF physiology. It describes bulk CSF flow from production site to absorption site.
Yamada, Shinya
core +2 more sources
Alzheimer's Research & Therapy, 2020 Cerebrospinal fluid biomarker profiles characterized by decreased amyloid-beta peptide levels and increased total and phosphorylated tau levels at threonine 181 (pT181) are currently used to discriminate between Alzheimer’s disease and other ...
Nicolas R. Barthélemy +7 more
semanticscholar +1 more source
Pyridoxal in the Cerebrospinal Fluid May Be a Better Indicator of Vitamin B6–dependent Epilepsy Than Pyridoxal 5′-Phosphate [PDF]
, 2020 Background We aimed to demonstrate the biochemical characteristics of vitamin B6–dependent epilepsy, with a particular focus on pyridoxal 5′-phosphate and pyridoxal in the cerebrospinal fluid. Methods Using our laboratory database, we identified patients
Akiyama, Tomoyuki +19 more
core +1 more source
Sleep Deprivation Affects Tau Phosphorylation in Human Cerebrospinal Fluid
Annals of Neurology, 2020 Tau hyperphosphorylation is an early step in tau‐mediated neurodegeneration and is associated with intracellular aggregation of tau as neurofibrillary tangles, neuronal and synaptic loss, and eventual cognitive dysfunction in Alzheimer disease.
Nicolas R. Barthélemy +5 more
semanticscholar +1 more source