Cerebrospinal fluid dynamics coupled to the global circulation in holistic setting: Mathematical models, numerical methods and applications. [PDF]
Toro EF +6 more
europepmc +2 more sources
Quantitative and Qualitative Analysis of CSF Flow Dynamics
Disorders of cerebrospinal fluid (CSF) secretion, dynamics and absorption are common in different illnesses and injuries of the central nervous system (CNS).
A. S. Tokarev +3 more
doaj +1 more source
MRI markers of cerebrospinal fluid dynamics predict dementia and mediate the impact of cardiovascular risk. [PDF]
INTRODUCTION: Impaired cerebrospinal fluid (CSF) dynamics may contribute to dementia, but human evidence is limited. We examined associations between magnetic resonance imaging-based proxies of CSF dynamics and incident dementia, and whether CSF ...
Hong H +5 more
europepmc +3 more sources
Alzheimer’s disease (AD) is a global health problem, with incidence and prevalence considered to increase during the next decades. However, no currently available effective treatment exists despite numerous clinical trials in progress. Moreover, although
Thomas Gabriel Schreiner +2 more
doaj +1 more source
Cerebrospinal fluid dynamics and discordant amyloid biomarkers. [PDF]
Do MRI-based metrics of a CSF-dynamics disorder, disproportionately enlarged subarachnoid-space hydrocephalus (DESH), correlate with discordant amyloid biomarkers (low CSF β-amyloid 1-42, normal Aβ-PET scan)? Individuals ≥50 years from the Mayo Clinic Study of Aging, with MRI, 11C-Pittsburgh compound B (Aβ) PET scans, and CSF phosphorylated-tau protein
Graff-Radford J +14 more
europepmc +4 more sources
Cerebrospinal fluid dynamics in non-acute post-traumatic ventriculomegaly
Background Post-traumatic hydrocephalus (PTH) is potentially under-diagnosed and under-treated, generating the need for a more efficient diagnostic tool. We aim to report CSF dynamics of patients with post-traumatic ventriculomegaly.
Afroditi D. Lalou +7 more
doaj +1 more source
Sheep are popular large animals in which to model human disorders and to study physiological processes such as cerebrospinal fluid dynamics. However, little is known about vascular compensatory mechanisms affecting cerebrospinal fluid pressures during ...
Nina Eva Trimmel +6 more
doaj +1 more source
Cisternal versus lumbar cerebrospinal fluid lactate concentration in healthy dogs
The analysis of cerebrospinal fluid biomarkers provides a wide range of information about the neurological health of a patient. Lactate is a metabolic precursor necessary for brain gluconeogenesis.
Alba Galan +6 more
doaj +1 more source
"Compensated hyperosmolarity" of cerebrospinal fluid and the development of hydrocephalus [PDF]
Acute osmolar loading of cerebrospinal fluid within one lateral ventricle of dogs was examined as a cause of water extraction from the bloodstream and an increase in intracranial pressure.
Vladić, Anton +4 more
core +1 more source
Cerebrospinal fluid supports viability and proliferation of cortical cells in vitro, mirroring in vivo development. [PDF]
Background The central nervous system develops around a fluid filled compartment. Recently, attention has turned to the potential role of the fluid (cerebrospinal fluid, CSF) in the developmental process.
Miyan Jaleel A +14 more
core +1 more source

