Results 141 to 150 of about 1,400,457 (288)

Gene Therapy for Amino Acid Decarboxylase Deficiency: Clinical and Imaging Outcomes in a French Cohort

Movement Disorders, EarlyView.
Abstract Background Intracerebral gene therapy is effective for amino acid decarboxylase (AADC) deficiency, but relationships between anatomical putaminal coverage, metabolic dynamics, and clinical recovery remain poorly understood. Objectives Assess safety, long‐term efficacy, and clinical–radiological correlations in a genetically diverse European ...
Clément Dunoyer, Gaëtan Poulen, Marie‐Céline François‐Heude, Eline Chauvet‐Piat, Bérénice Lecardonnel, Emmanuel Roze, Marie‐Ange Nguyen Morel, Domitille Gras, Adeline Quintard, Gaelle Baroux, Pierre Meyer, Philippe Coubes, Christophe Milesi, Julien Baleine, Chrystelle Sola, Vivien Szabo, Bénédicte Delye, Jana Haberlova, Mohamed Osman Eltahir Babiker, Mohammed Al Muqbil, Stéphanie Sanchez, Souad Touati, Nicolas Leboucq, Virginie Kouyoumdjian, Sylvia Sanquer, Denis Mariano‐Goulart, Thomas Roujeau, Agathe Roubertie   +27 more
wiley   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal, Katherine A. Dudley, Stacey Sullivan, Kate T. Brizzi, Katherine M. Burke, Sydney Hall, Kiersten Pease, Joshua N. Goldstein, James D. Berry, Doreen T. Ho   +9 more
wiley   +1 more source

Intracranial Haematoma Concealed by Leakage of Cerebrospinal Fluid [PDF]

BMJ, 1956
openaire   +2 more sources

Idiopathic Intracranial Hypertension Associated With Transverse Sinus Giant Arachnoid Granulation Successfully Treated by Endovascular Stenting

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT The incidence of Idiopathic intracranial hypertension (IIH), defined as increased intracranial pressure of unknown origin, has been reported to be very low in Japan. A 42‐year‐old Japanese woman was admitted to our hospital with headache, blurred vision, and tinnitus.
Hiroka Sakaguchi, Mizuki Tagami, Akira Ueda, Satoshi Nozuchi, Kosuke Okamoto, Itsuki Hasegawa, Shigeru Honda, Yusuke Watanabe, Mio Nakamine, Takeo Goto, Yoshiaki Itoh   +10 more
wiley   +1 more source

Serum elemental profile‐based machine learning models for Alzheimer's disease identification and cognitive score prediction

Neuroprotection, EarlyView.
Serum elemental profiling combined with machine learning supports exploratory Alzheimer's disease (AD) identification and cognitive score prediction. In this retrospective cross‐sectional study, 874 participants from the BANC‐PUMC, including cognitively normal controls and patients with AD, were analyzed.
Haotian Liu, Xinnan Liu, Yashuang Chen, Meng Pan, Ying Fu, Chao Ma, Wei Ge   +6 more
wiley   +1 more source

Chronic high‐altitude exposure and intracerebral hemorrhage: A novel perspective from the vascular‐immune‐neuronal network

Neuroprotection, EarlyView.
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang, Linjie Wei, Mingxi Li, Bo Wu, Rongjian Ouyang, Gang Zhu, Yujie Chen   +6 more
wiley   +1 more source

Immediate Resumption of Positive Airway Pressure Following Sinus Surgery: A Prospective Controlled Multicenter Study

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Untreated obstructive sleep apnea (OSA) in the perioperative period confers significant cardiopulmonary risk. However, many otolaryngologists defer restarting positive airway pressure (PAP) therapy following functional endoscopic sinus surgery (FESS) due to perceived risk of epistaxis, mucosal injury, and wound healing.
Garret Choby, Jose L. Mattos, Erin K. O'Brien, Devyani Lal, Michael J. Marino, Spencer Payne, Carlos N. Pinheiro‐Neto, Nicholas R. Rowan, Anthony Tang, Eric W. Wang, Janalee Stokken   +10 more
wiley   +1 more source

Identification of Cerebrospinal Fluid Leakage by Cisternography in Recurrent Meningitis Associated With Inner Ear Malformation. [PDF]

Cureus
Oshika S, Kabaya K, Moribe K, Iwasaki S.
europepmc   +1 more source

Applications and prospects of artificial intelligence and digital medicine in pediatric nasal skull base tumors

Pediatric Investigation, EarlyView.
Pediatric nasal skull base tumors present diagnostic and therapeutic challenges due to their deep location, nonspecific symptoms, and the narrow nasal cavity in children. Although artificial intelligence (AI) and digital medicine have advanced early diagnosis, multidisciplinary treatment, and prognosis, their application in these rare tumors remains ...
Xiuping Wu, Jing Wei, Chen Liu, Pengpeng Wang, Wentong Ge, Yang Han   +5 more
wiley   +1 more source

Pneumocephalus with suspected cerebrospinal fluid leakage after epiduroscopic epidural neuroplasty: a case report. [PDF]

Ewha Med J
Kang MJ, Kang BK, Yoo SH, Kim WJ.
europepmc   +1 more source