Results 211 to 220 of about 1,400,457 (288)

Brain strain: Blood flow and metabolism in environmental extremes

open access: yesExperimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak   +3 more
wiley   +1 more source

Thermoregulatory and plasma neurobiomarker responses to heat tolerance assessment in exertional heat illness and matched controls

open access: yesExperimental Physiology, EarlyView.
Abstract Exercise in the heat and elevated tissue temperature are associated with neuronal stress and changes in blood–brain barrier (BBB) function. More severe thermal insult may manifest as exertional heat illness (EHI) and complication by central nervous system (CNS) dysfunction may persist post‐EHI.
Tom W. Palin   +15 more
wiley   +1 more source

Dural Injury During Spinal Surgery and Postoperative Cerebrospinal Fluid Leakage: A Single-Center Experience. [PDF]

open access: yesCureus
Kinoshita H   +9 more
europepmc   +1 more source

Deletion of the sodium leak channel NALCN in dopamine neurons alters D2R‐mediated signalling and psychostimulant responsiveness

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The sodium leak channel NALCN is an important contributor to the spontaneous pacemaker activity of midbrain dopamine neurons and is required for proper presynaptic D2 autoreceptor signalling at dopaminergic terminals. Conditional deletion of NALCN in dopamine neurons enhances psychomotor sensitization to amphetamine and cocaine ...
Angelina Rogliardo   +16 more
wiley   +1 more source

Electrophysiological properties of the dorsal motor nucleus of the vagus motoneurones controlling airway mucus secretion in rats

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Acidosis depolarises parasympathetic respiratory motoneurones in the dorsal motor nucleus of the vagus (DMV) and increases their firing frequency by reducing TWIK‐2 channel conductance. Acidosis also activates astrocytes, which further enhance neuronal excitability through NMDA receptor‐dependent glutamatergic signalling.
Daniel P. de Souza   +4 more
wiley   +1 more source

Mechanical Characterization of Cervical Spinal Cord Tissue Under Varied Environmental Conditions

open access: yesProceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.
ABSTRACT Identifying material parameters for cervical spinal cord tissue requires an understanding of how testing protocols affect the measured response. We use ovine cervical spinal cord white matter to examine the effects of hydration, temperature, adhesive fixation and repeated loading.
Hanwen Zhang, Bernd Markert
wiley   +1 more source

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