Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
The Examination of Prognostic Factors and Treatment Strategies for Traumatic Cerebrospinal Fluid Leakage. [PDF]
CureusShizawa K +10 more
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Medicinal Research Reviews, Volume 46, Issue 6, Page 1897-1921, November 2026.ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu +2 more
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Endoscopic nasal multilevel skull base reconstruction combined with lumbar cistern drainage in the treatment of infection caused by cerebrospinal fluid leakage: A case report. [PDF]
Medicine (Baltimore)Zhou L, Yang X, Lv J, Chong Z.
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Magnetic Resonance in Medicine, Volume 96, Issue 5, Page 2309-2320, November 2026.ABSTRACT Purpose To determine the feasibility of measuring brain clearance of gadolinium contrast agent using standard intravenous DCE‐MRI acquisitions and evaluate the contribution of blood–brain barrier (BBB) and non‐BBB clearance routes. Methods Uptake and extended Tofts models were fit to DCE‐MRI data from people with Parkinson's disease, post ...
Martin Kozár +8 more
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Cerebrospinal Fluid Leakage Combined with Blood Biomarkers Predicts Poor Wound Healing After Posterior Lumbar Spinal Fusion: A Machine Learning Analysis. [PDF]
Int J Gen MedPang Z +9 more
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Using Manganese‐Enhanced DCE‐MRI to Assess Blood‐Cerebrospinal Fluid Barrier Transport
Magnetic Resonance in Medicine, Volume 96, Issue 5, Page 2083-2091, November 2026.ABSTRACT PurposeWe developed a dynamic, heavily T2‐weighted (hT2w) FLAIR protocol to resolve acute Mn2+ transport kinetics, as a proxy for Ca2+, across the choroid plexus (ChP)—cerebrospinal fluid (CSF) interface, in vivo. By quantifying intercompartmental Mn2+ dynamics, and comparing these with Gd‐DOTA, we sought to characterize blood‐CSF‐barrier ...
Charith Perera +9 more
wiley +1 more source
A Case of Bilateral Idiopathic Temporal Cerebrospinal Fluid Leakage With Multiple Fistulas in the Middle and Posterior Cranial Fossae Closed Using the Transmastoid Approach. [PDF]
CureusOhira S, Komori M.
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High‐Resolution IVIM MRI Characterizes Diffusion–Perfusion Properties of the Parasagittal Dura
NMR in Biomedicine, Volume 39, Issue 11, November 2026.Parasagittal dura demonstrates intermediate diffusion and elevated perfusion‐related IVIM metrics compared with brain parenchyma, reflecting its unique microfluidic environment at the CSF–dura interface. IVIM imaging of the parasagittal dura provides a rapid, noncontrast MRI approach to assess dural fluid transport and may offer a potential imaging ...
Yi‐Jui Liu +8 more
wiley +1 more source
The drainage volume control by elevation of drainage height versus head down tilt in supine position for management of cerebrospinal fluid leakage following lumbar posterior surgery. [PDF]
BMC Musculoskelet DisordDong P, Huang J, Deng X, Yang H, Luo C.
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