Results 71 to 80 of about 113,579 (302)
Revista Educação em Saúde, 2015 Objective: To present and analyze the sample laboratory findings of cerebrospinal fluid of patients with lung tumor. Case report and comments: Laboratory data analyzed were derived from the cerebrospinal fluid routine examination, culture, resistant acid-
Heitor Gomes de Souza Pereira +1 more
doaj
Advanced Healthcare Materials, EarlyView.Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco +7 more
wiley +1 more source
Advanced Materials, EarlyView.A thermally adaptive plasmonic metasurface, functionalized with poly(N‐isopropylacrylamide) (PNIPAM) and anti‐CD63 antibodies, enables precise, on‐demand capture and release of extracellular vesicles (EVs). Delivering high recovery, improved purity, and intact vesicle structure, the platform offers a versatile, label‐free solution for real‐time EV ...
Beyza Nur Kucuk +7 more
wiley +1 more source
Profiling cerebrospinal fluid proteins in Alzheimer's disease [PDF]
, 2011 Alzheimer’s disease (AD) is a progressive, irreversible, neurodegenerative disease that affects more than 5 million people in USA alone and is expected to increase to 7 million by 2020. Currently, there are no drugs available that can halt or prevent the
Krishnamachari, Sesha
core +1 more source
European Journal of Cell BiologyThe blood–cerebrospinal fluid barrier (BCSFB) is formed by the choroid plexus and represents the interface between the blood and cerebrospinal fluid (CSF).
Petra Majerova +8 more
doaj +1 more source
Label‐Free Detection of a Neurotransmitter Using an Aptamer‐Functionalized Amorphous IGZO Transistor
Advanced Materials Interfaces, EarlyView.An aptamer‐functionalized amorphous IGZO thin‐film transistor enables label‐free electrical detection of the neurotransmitter serotonin under liquid‐gated operation. Stepwise surface functionalization ensures stable biomolecule integration and efficient electrostatic coupling.
Ngoc Thanh Ho +3 more
wiley +1 more source
Depletion of highly abundant proteins from human cerebrospinal fluid: a cautionary note [PDF]
, 2015 Affinity-based techniques, both for enrichment or depletion of proteins of interest, suffer from unwanted interactions between the bait or matrix material and molecules different from the original target.
Krause, Eberhard +9 more
core +1 more source
Fatigue in primary Sjögren’s syndrome: A proteomic pilot study of cerebrospinal fluid
SAGE Open Medicine, 2019 Objectives: Fatigue is a frequent and often disabling phenomenon that occurs in patients with chronic inflammatory and immunological diseases, and the underlying biological mechanisms are largely unknown.
Eivind Larssen +9 more
doaj +1 more source
A chronic fatigue syndrome – related proteome in human cerebrospinal fluid
BMC Neurology, 2005 Background Chronic Fatigue Syndrome (CFS), Persian Gulf War Illness (PGI), and fibromyalgia are overlapping symptom complexes without objective markers or known pathophysiology. Neurological dysfunction is common.
Baraniuk James N +5 more
doaj +1 more source
Advanced Science, EarlyView.Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng +8 more
wiley +1 more source