Results 71 to 80 of about 58,328 (279)
Elevation in circulating YKL-40 concentration in patients with cerebrovascular disease
YKL-40 is a novel inflammatory protein. Elevated serum levels of YKL-40 have been reported in patients with atherosclerosis and other cardiovascular diseases, but the circulating profile of YKL-40 in patients with cerebrovascular disease has been less investigated.
Jia Xu+7 more
openaire +5 more sources
AI‐Driven Microphysiological Systems for Advancing Nanoparticle Therapeutics
This review outlines recent advances in integrating artificial intelligence with microphysiological systems for nanoparticle evaluation. It highlights data‐driven optimization, image‐based prediction, and AI‐enabled analysis frameworks that advance translational research and support the development of personalized nanomedicine. Nanoparticles (NPs) play
Yedam Lee+3 more
wiley +1 more source
Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives
ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos+8 more
wiley +1 more source
Management of Lost Atherectomy Devices in the Coronary Arteries
ABSTRACT Rotational and orbital atherectomy are important tools to treat calcific coronary disease. Entrapment of an atherectomy device, that is, rotational atherectomy burr or orbital atherectomy crown, is a serious complication during atherectomy. Loss of an atherectomy device is a more challenging complication that usually follows device entrapment.
Gregor Leibundgut+8 more
wiley +1 more source
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) continues to be an increasingly common health problem associated with a high mortality rate. Elevated levels of Growth differentiation factor‐15 (GDF15) and N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) are reportedly associated with poor clinical outcomes in a broad range of ...
Yoichiro Otaki+11 more
wiley +1 more source
In patients with Acute Myocardial Infarction related heart failure, the in‐hospital administration of ARNIs was associated with a reduced risk of MACEs and re‐hospitalizations for heart failure, as well as cardiac remodeling, compared to standard therapy.
Gianluca Di Pietro+15 more
wiley +1 more source
Abstract Objectives Acute cerebral ischemia is characterized by several pathological processes evolving during time, which contribute to the final tissue damage. Secondary processes, such as prolonged inflammatory response, impaired mitochondrial function and oxidative stress, are responsible for the progression of brain injury to the peri‐infarct area,
Fioravante Capone+8 more
wiley +1 more source
Abstract Aims Immune checkpoint inhibitors (ICI) are the cornerstone of modern oncology; however, side effects such as ICI‐related myocarditis (irM) can be fatal. Recently, Bonaca proposed criteria for irM; however, it is unknown if they correlate well with cardiovascular (CV) ICI‐related adverse events.
Lorenzo Braghieri+12 more
wiley +1 more source
Abstract Aims Mortality in cardiogenic shock (CS) remains elevated, with the potential for CS causes to impact prognosis and risk stratification. The aim was to investigate in‐hospital prognosis and mortality in CS patients according to aetiology. We also assessed the prognostic accuracy of CardShock and IABP‐SHOCK II scores.
Cosme García‐García+17 more
wiley +1 more source
Endovascular Treatment in the Subclavian Steal Syndrome
When the proximal occlusion or stenosis of the subclavian or of the brachiocephalic artery may require distal arterial filling through reversal flow from the vertebral artery, causing clinically significant blood supply reduction to the brainstem, it is ...
Luana Antunes Maranha Gatto+5 more
doaj +1 more source