Results 81 to 90 of about 3,152,690 (357)

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

open access: yesAdvanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park   +7 more
wiley   +1 more source

Effect of Low Diastolic Blood Pressure to Cardiovascular Risk in Patients With Ischemic Stroke or Transient Ischemic Attacks Under Different Systolic Blood Pressure Levels

open access: yesFrontiers in Neurology, 2020
Background: In the context of recently updated strategies of pressure management, there is a paucity of evidence on the effect of diastolic blood pressure (DBP) level on adverse events among stroke patients.
Zimo Chen   +39 more
doaj   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

open access: yesAdvanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar   +7 more
wiley   +1 more source

Differential neuropsychological profiles in Parkinsonian patients with or without vascular lesions. [PDF]

open access: yes, 2010
The purpose of this study is to compare the neuropsychological profile of patients affected by parkinsonism and vascular lesions to that in patients with PD alone (PD) and to evaluate whether the brain vascular lesion load is associated with ...
Antonini A   +6 more
core  

Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice

open access: yesAdvanced Science, EarlyView.
This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang   +16 more
wiley   +1 more source

A Tractography-Based Grading Scale of Brain Arteriovenous Malformations Close to the Corticospinal Tract to Predict Motor Outcome After Surgery

open access: yesFrontiers in Neurology, 2019
Background: Surgical decision-making for brain arteriovenous malformations (AVMs) close to the corticospinal tract (CST) is always challenging. The purpose of this study was to develop a tractography-based grading scale to improve preoperative risk ...
Maogui Li   +31 more
doaj   +1 more source

Prognostic Value of Elevated Cardiac Troponin I After Aneurysmal Subarachnoid Hemorrhage

open access: yesFrontiers in Neurology, 2021
Object: Patients with aneurysmal subarachnoid hemorrhage (aSAH) have an increased incidence of cardiac events and short-term unfavorable neurological outcomes during the acute phase of bleeding.
Fa Lin   +36 more
doaj   +1 more source

Epidemiology of transient ischemic attacks in the structure of acute cerebrovascular disorders in Ukraine and in other countries

open access: yes, 2017
Background. Few epidemiological data are available regarding the prevalence and incidence of transient ischemic attack (TIA). The purpose of our work was to analyze the epidemiology of transient ischemic attacks in the structure of acute cerebrovascular ...
S. M. Vinychuk, O. Fartushna
semanticscholar   +1 more source

Interventions for neurocognitive dysfunction [PDF]

open access: yes, 2017
Purpose of review: To evaluate current barriers to HIV cure strategies and interventions for neurocognitive dysfunction with a particular focus on recent advancements over the last three years. Recent findings: Optimal anti-retroviral therapy (ART) poses
Brew, B, Ellero, J, Lubomski, M
core   +2 more sources

Gompertz Law‐Based Biological Age (GOLD BioAge): A Simple and Practical Measurement of Biological Ageing to Capture Morbidity and Mortality Risks

open access: yesAdvanced Science, EarlyView.
The Gompertz law‐based biological age metric (GOLD BioAge) introduces interpretable convenient and interpretable calculations to capture mortality, disease, and frailty risks. Its applications to proteomics and metabolomics (ProtAge and MetAge) demonstrate clinical potential to enhance aging evaluation and prevent age‐related diseases.
Meng Hao   +14 more
wiley   +1 more source

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