Retinal vascular reactivity is associated with white matter hyperintensities and dysfunctional cerebrovascular reactivity in cerebral small vessel disease. [PDF]
Blair GW +10 more
europepmc +1 more source
Abstract Central artery stiffening increases the haemodynamic pulsations transmitted downstream towards target organs, including the brain. While recent evidence suggests that long duration spaceflight is associated with reduced common carotid artery (CCA) distensibility, cerebrovascular pulsatility has not been extensively characterized in astronauts.
Roxanne Fournier +5 more
wiley +1 more source
Microglia modulate the cerebrovascular reactivity through ectonucleotidase CD39. [PDF]
Fu Z +17 more
europepmc +1 more source
Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley +1 more source
Assessing and Improving the Reproducibility of Cerebrovascular Reactivity Evaluations in Healthy Subjects Using Short-Breath-Hold fMRI. [PDF]
Renger E +4 more
europepmc +1 more source
Abstract Individuals with persisting post‐concussion symptoms with physiological subtype (PPCS‐P) demonstrate exercise intolerance due to exacerbation of concussion‐like symptoms during incremental exercise. We tested the hypothesis that individuals with PPCS‐P (n = 12) would have a blunted cardiac autonomic response to face cooling compared to healthy
Phillip J. Wallace +6 more
wiley +1 more source
Optimizing cerebrovascular endothelial health through shear stress modulation
Abstract The endothelium plays a pivotal role in regulating cerebrovascular blood flow, and its dysfunction increases the risk of cerebrovascular disease. Endothelial shear stress, a primary mechanical stimulus for endothelial nitric oxide production, is a key modulator of vascular adaptation.
Erika Iwamoto +2 more
wiley +1 more source
Correlation of cerebrovascular reactivity and STA-MCA bypass flow
Dr. Martina Sebök +5 more
doaj +1 more source
The influence of cardiovascular fitness and ventilatory efficiency on fMRI assessed cerebrovascular reactivity in older adults. [PDF]
Novak TS +6 more
europepmc +1 more source
Abstract Dynamic cerebral autoregulation (dCA) stabilises cerebral blood flow (CBF) against rapid fluctuations in perfusion pressure and may serve as a key physiological mediator of cognitive function. Inhibitory executive function, a core domain essential for goal‐directed behaviour, is influenced by modifiable lifestyle factors such as physical ...
Hayato Tsukamoto, Damian M. Bailey
wiley +1 more source

