Effect and Mechanism of lncRNA CERS6-AS1 on the Biological Behavior of Prostate Cancer Cell
Applied Bionics and Biomechanics, 2022 Objective. To investigate the effect of long noncoding RNA (lncRNA) CERS6 antisense RNA1 (CERS6-AS1) on the biological behavior of prostate cancer cells DU145 and its mechanism. Methods.
Fu Huang, Li Quan Zhou
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CERS6‐AS1 contributes to the malignant phenotypes of colorectal cancer cells by interacting with miR‐15b‐5p to regulate SPTBN2 [PDF]
Kaohsiung Journal of Medical Sciences, 2022 Accumulating evidence indicates that long noncoding RNAs (lncRNAs) act as tumor promoters or suppressors in various types of cancer. Previous investigations suggest that ceramide synthase 6 (CERS6) antisense RNA 1 (CERS6‐AS1) acts as an oncogene in ...
Shi‐Yu Zhao +6 more
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CERS6‐AS1 promotes cell proliferation and represses cell apoptosis in pancreatic cancer via miR‐195‐5p/WIPI2 axis [PDF]
Kaohsiung Journal of Medical Sciences, 2022 Pancreatic cancer (PC) is a lethal malignancy that threatens human health. Long noncoding RNAs (lncRNAs) act as important mediators in PC development. Our study aimed to investigate the function and mechanism of lncRNA ceramide synthase 6 antisense RNA 1
Kan‐Fei Gao +4 more
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Retracted: Effect and Mechanism of lncRNA CERS6-AS1 on the Biological Behavior of Prostate Cancer Cell [PDF]
Applied Bionics and Biomechanics, 2023 Applied Bionics and Biomechanics, Volume 2023, Issue 1, 2023.
Applied Bionics and Biomechanics
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Long noncoding RNA CERS6‐AS1 functions as a malignancy promoter in breast cancer by binding to IGF2BP3 to enhance the stability of CERS6 mRNA [PDF]
Cancer Medicine, 2020 Breast cancer (BC) leads to the highest mortality in women worldwide, characterized by inevitable proliferation and metastasis of BC cells. Mounting evidence confirm that lncRNAs play a significant role in the tumorigenesis and development of BC.
Gang Bao +4 more
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LncRNA CERS6-AS1 promotes proliferation and metastasis through the upregulation of YWHAG and activation of ERK signaling in pancreatic cancer [PDF]
Cell Death and Disease, 2021 LncRNAs play essential regulatory roles in pancreatic cancer (PC) tumorigenesis and progression. We aimed to investigate the role of lncRNA CERS6-AS1 in PC. CERS6-AS1 expression was determined in PC tissues and cell lines by PCR analysis.
Jian Xu +7 more
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Long noncoding RNA CERS6-AS1 modulates glucose metabolism and tumor progression in hepatocellular carcinoma by promoting the MDM2/p53 signaling pathway [PDF]
Cell Death Discovery, 2022 Hepatocellular carcinoma (HCC) is one of the most serious malignant cancers and has a high fatality rate. However, clinical strategies for the effective treatment of HCC remain lacking.
Bo Xu +6 more
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lncRNA CERS6-AS1 upregulates the expression of ANLN by sponging miR-424-5p to promote the progression and drug resistance of lung adenocarcinoma [PDF]
Non-coding RNA ResearchLong non-coding RNAs (lncRNAs) play a crucial role in tumor generation and progression. However, the exact functional significance and underlying molecular mechanism by which lncRNA CERS6-AS1 operates in the context of lung adenocarcinoma (LUAD) remain ...
Zhuo Ting +10 more
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Revisiting tricuspid regurgitation: Historical insights and emerging research perspectives. [PDF]
Eur J Clin InvestTricuspid regurgitation (TR), once seen as benign, is now recognized as a serious and increasingly prevalent condition linked to aging and better imaging. Its association with greater morbidity and mortality has shifted clinical perspectives towards early diagnosis and intervention.
Gonzalez-Cucharero C +5 more
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Integrative Analyses of Genes Associated With Right Ventricular Cardiomyopathy Induced by Tricuspid Regurgitation [PDF]
Frontiers in Genetics, 2021 Tricuspid regurgitation (TR) induces right ventricular cardiomyopathy, a common heart disease, and eventually leads to severe heart failure and serious clinical complications.
Chengnan Tian +13 more
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