Results 41 to 50 of about 7,828 (111)

DataSheet_7_Long Non-Coding RNA CD27-AS1-208 Facilitates Melanoma Progression by Activating STAT3 Pathway.zip

, 2022
Melanoma is the most lethal skin cancer that originates from epidermal melanocytes. Recently, long non-coding RNAs (lncRNAs) are emerging as critical regulators of cancer pathogenesis and potential therapeutic targets.
Tao Zhao (341704), Jingjing Ma (419752), Tianwen Gao (262800), Peng Xu (17962), Qiong Shi (244677), Xiuli Yi (166944), Yuqi Yang (1608304), Weinan Guo (4727631), Sen Guo (1846828), Lin Liu (74495), Chunying Li (166955), Weigang Zhang (1333242), Yu Liu (6938), Qiao Yue (11939732)   +13 more
core   +1 more source

DataSheet_4_Long Non-Coding RNA CD27-AS1-208 Facilitates Melanoma Progression by Activating STAT3 Pathway.zip

, 2022
Melanoma is the most lethal skin cancer that originates from epidermal melanocytes. Recently, long non-coding RNAs (lncRNAs) are emerging as critical regulators of cancer pathogenesis and potential therapeutic targets.
Tao Zhao (341704), Jingjing Ma (419752), Tianwen Gao (262800), Peng Xu (17962), Qiong Shi (244677), Xiuli Yi (166944), Yuqi Yang (1608304), Weinan Guo (4727631), Sen Guo (1846828), Lin Liu (74495), Chunying Li (166955), Weigang Zhang (1333242), Yu Liu (6938), Qiao Yue (11939732)   +13 more
core   +1 more source

Generation of CerS6^ADAAAIA mice.

, 2022
The CerS6 genomic region showing the CRISPR/Cas9 design for editing the CerS6 DDRSDIE motif. Genomic location (mm10 chr2:68,861,441–69,114,282) of the guide RNA cleavage site is shown as a dashed line.
Tammar Joseph (13113473), Shifra Ben-Dor (539029), Anthony H. Futerman (440004), Jiyoon Kim (758075), Yael Pewzner-Jung (587457)   +4 more
core   +1 more source

Image_8_Long Non-Coding RNA CD27-AS1-208 Facilitates Melanoma Progression by Activating STAT3 Pathway.tif

, 2022
Melanoma is the most lethal skin cancer that originates from epidermal melanocytes. Recently, long non-coding RNAs (lncRNAs) are emerging as critical regulators of cancer pathogenesis and potential therapeutic targets.
Tao Zhao (341704), Jingjing Ma (419752), Tianwen Gao (262800), Peng Xu (17962), Qiong Shi (244677), Xiuli Yi (166944), Yuqi Yang (1608304), Weinan Guo (4727631), Sen Guo (1846828), Lin Liu (74495), Chunying Li (166955), Weigang Zhang (1333242), Yu Liu (6938), Qiao Yue (11939732)   +13 more
core   +1 more source

Proposed two-step mechanism for CerS6-dependent MTX cytotoxicity.

, 2016
Step 1: MTX induces p53, which functions as the transcriptional activator of CerS6 and increases levels of the protein in ER. Step 2: MTX induces ER stress leading to aggregation of CerS6-containing ER membranes.
Natalia I. Krupenko (439696), Amin Esmaeilniakooshkghazi (846617), Baharan Fekry (846616), Sergey A. Krupenko (439695)   +3 more
core   +1 more source

The complex regulatory network of the 336 unique proteins interacted with BVES-AS1-201-50aa.

, 2023
The complex regulatory network of the 336 unique proteins interacted with BVES-AS1-201-50aa.
Weiwei Zheng (140828), Yucheng Song (14231285), Yingchang Guo (16425979), Guangtan Zhang (16425982), Xuebin Bao (16425988), Junwei Bai (9730322), Xiaofei Song (3111648), Qinhui Zhu (16425985), Chao Zhang (51048), Gang Wu (23885)   +9 more
core   +1 more source

Integrated Analysis of Cuproptosis Regulators Reveals Prognostic Significance and Therapeutic Targets in IDH1 Mutant Glioma

MedComm – Future Medicine, Volume 4, Issue 1, March 2025.
This study performed a comprehensive analysis of cuproptosis‐related genes (CRGs) in IDH1‐mutant glioma samples from the TCGA database. Two novel IDH1‐mutant glioma subtypes were identified based on CRG expression patterns. FDX1 and SLC31A1 were identified as key regulators.
Yuxuan Luan, Yong Meng, Chunming Sun, Ruixin Wu, Qimeng Chang, Yilin Wang, Minfeng Shu   +6 more
wiley   +1 more source

Osteoarthritis Bone Marrow MSCs Retain Regenerative Competence and Chemokine Responsiveness for Drug‐Based In Situ Tissue Engineering

Stem Cells International, Volume 2025, Issue 1, 2025.
Background Mesenchymal stromal cells (MSCs) support tissue repair in osteoarthritis (OA), with migration to damaged tissue being a key strategy in in situ tissue engineering. Their regenerative potential depends on factors such as differentiation, level of senescence, and responsiveness to signaling molecules.
Julia Sonnleitner, Katja Gulich, Axel Pruss, Carsten Perka, Angelika Gursche, Daniel Kendoff, Michael Sittinger, Shabnam Hemmati-Sadeghi, Tilo Dehne, Yuriy Petrenko   +9 more
wiley   +1 more source

CERS6 promotes ESCC cell proliferation by increasing the stability of RPN1

, 2023
Esophageal squamous cell carcinoma (ESCC) has a poor prognosis because it is typically diagnosed at a moderate or advanced stage. Investigating the precise molecular mechanism of ESCC pathogenesis is essential for developing new therapeutic strategies ...
Kangdong Liu (14143195), Yanan Jiang (16832245), Yuhan Zhang (2792089), Yuxin Zhai (2499973), Junyong Wang (3807964), Dan Gao (410390), Qiong Wu (84327), Jimin Zhao (482148), Weizhe Zhang (286664), Zhiying Zhao (188792), Xiaoxiao Yang (3800128), Xiaokun Zhao (212561), Nannan Zhao (4331221), Zigang Dong (180050), Wenjing Chen (383602), Qiang Yuan (240079)   +15 more
core   +1 more source

Abstracts of the 79th Annual Meeting of the Japanese Cancer Association; 2020 Oct 1‐3; Hiroshima, Japan as Cancer Science, Supplement 1, Vol 112 (2021)

, 2021
Cancer Science, Volume 112, Issue S1, Page 1-1072, February 2021.
wiley   +1 more source