Results 11 to 20 of about 7,828 (111)
Systematic identification of pathological mechanisms, prognostic biomarkers and therapeutic targets by integrating lncRNA expression variation in salivary gland mucoepidermoid carcinoma [PDF]
Scientific ReportsBiological processes intricately intertwine with tumorigenesis, significantly influencing treatment outcomes and prognosis. However, the mechanisms fostering mucoepidermoid carcinoma (MEC) remain inadequately elucidated. This research utilizes expression
Yan-ping Zou +6 more
doaj +2 more sources
Kaohsiung J Med Sci, 2022 The Kaohsiung Journal of Medical Sciences, Volume 38, Issue 10, Page 1024-1025, October 2022.
europepmc +2 more sources
The evolving process of ferroptosis in thyroid cancer: Novel mechanisms and opportunities. [PDF]
J Cell Mol MedAbstract Thyroid cancer (TC) is a prevalent endocrine malignancy, with a significant increase in incidence worldwide. Ferroptosis is a novel form of programmed cell death, primarily caused by iron overload and reactive oxygen species (ROS)‐dependent accumulation of lipid peroxides.
Yin L, Luo X, Zhang X, Cheng B.
europepmc +2 more sources
The Expanding Roles of Long Non‐Coding RNAs in Pancreatic Cancer
Advanced Therapeutics, Volume 6, Issue 12, December 2023., 2023 This review summarizes the roles of long non‐coding RNAs (lncRNAs) in occurrence, development, and therapeutic resistance of pancreatic cancer by categorizing regulation of epigenetic inheritance, transcription, post‐transcription, and related signaling pathways.
Yu Yan +7 more
wiley +1 more source
Frontiers in Oncology, 2020 Growing evidence has illustrated critical roles of competing endogenous RNA (ceRNA) regulatory network in human cancers including hepatocellular carcinoma.
Junjie Zhang, Weiyang Lou
doaj +1 more source
Cabazitaxel suppresses colorectal cancer cell growth via enhancing the p53 antitumor pathway
FEBS Open Bio, Volume 11, Issue 11, Page 3032-3050, November 2021., 2021 In the present study, we screened 160 drugs approved by the Food and Drug Administration, aiming to identify novel chemotherapeutic agents for colorectal cancer (CRC) treatment. We identified that the microtubule inhibitor cabazitaxel (CBT) has a suppressive effect on CRC cells both in vitro and in vivo. Transcriptome analysis revealed that CBT induced
Wen Zhang +9 more
wiley +1 more source
Screen and identification of BVES-AS1-201-50aa.
, 2023 (A) Venn diagram showed the lncRNAs that are aberrant expression in CRC, are associated with poor prognosis of CRC patients, and are predicted to have encoding potential.
Weiwei Zheng (140828) +9 more
core +1 more source
CEBPγ facilitates lamellipodia formation and cancer cell migration through CERS6 upregulation
Cancer Science, Volume 112, Issue 7, Page 2770-2780, July 2021., 2021 Schematic illustration showing CEBPγ functions for cancer cell migration. Abstract Ceramide synthase 6 (CERS6) promotes lung cancer metastasis by stimulating cancer cell migration. To examine the underlying mechanisms, we performed luciferase analysis of the CERS6 promoter region and identified the Y‐box as a cis‐acting element.
Hanxiao Shi +17 more
wiley +1 more source
, 2022 This study aimed to investigate the roles of microRNA-886 (miR-886) and long non-coding RNA (lncRNA) OXCT1-AS1 in osteosarcoma (OS). We predicted that they might interact with each other.
Han Liu (288039), Wen Dai (1607932)
core +1 more source
Lipid metabolism in cancer progression and therapeutic strategies
MedComm, Volume 2, Issue 1, Page 27-59, March 2021., 2021 Lipid metabolic reprogramming‐mediated crosstalk between cancer cells and tumor microenvironment contributes to cancer progression. Stromal cells, such as adipocyte, CAF, epithelia cells contribute to lipid metabolic reprogramming in cancer cells. Cancer cells undergo lipid metabolism rewiring to generate building materials for membrane, lipid second ...
Yan Fu +11 more
wiley +1 more source