Results 151 to 160 of about 359,951 (311)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Enhancement of Collagen and Elastic Fibers by Direct Contact Cooling–Based Monopolar Radiofrequency in a Minipig Model

Clinical, Cosmetic and Investigational Dermatology
Hyeyoon Goo,1 Chayeon Kim,2 Namgue Hong,1 Yea-Jin Lee,1 Eun Young Kim,1 Sun-Hyang Choi,1 Ji On Park,1,3 Mun-Hui Baek,1,3 Su Ji Hwang,1,3 Jae Won Lee,1,3 Wonho Lee,2 Ryeohoon Kim,4 Yongjik Lee,2 Jin-Chul Ahn1,31Medical Laser Research Center, Graduate ...
Goo H, Kim C, Hong N, Lee YJ, Kim EY, Choi SH, Park JO, Baek MH, Hwang SJ, Lee JW, Lee W, Kim R, Lee Y, Ahn JC   +13 more
doaj  

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Certification of William Frederick Milton Arny

Certification dated February 10, 1865 by William Frederick Milton Arny, Secretary of the Territory of New Mexico, for copies of the Revised Laws of the Territory of New Mexico, Legislature, 1865. Page 2 is the translation into Spanish.

core  

If You Can't Trust the Farmer, Who Can You Trust? The Effect of Certification Types on Purchases of Organic Produce [PDF]

An information asymmetry exists in the market for organic produce since consumers cannot determine whether produce is organically or conventionally grown.
Hunnicutt, Lynn, Ward, Ruby A., Keith, John E.   +2 more
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Proficiency in lung ultrasound and perceived barriers to adoption among emergency physicians after a short pneumonia training programme: a multicentre observational study in Swiss emergency department. [PDF]

BMJ Open
Bessat C, Erard A, Roux A, Brahier T, Suttels V, Bingisser R, Schwendinger M, Bulaty T, Fournier Y, Della Santa V, Pfeil M, Schwab D, Leuppi JD, Geigy N, Steuer S, Roos F, Christ M, Sirova A, Atzl A, Napieralski F, Tagan D, Albricht WC, Hugli O, Boillat-Blanco N, Garcia E.   +24 more
europepmc   +1 more source