Reactogenicity of Cervarix and Gardasil human papillomavirus (HPV) vaccines in a randomized single blind trial in healthy UK adolescent females [PDF]
One hundred and ninety eight females aged 12–15 y were enrolled in an observer-blinded randomized trial to assess the immunogenicity and reactogenicity of the tetravalent HPV vaccine Gardasil® (group 2), in comparison to the bivalent HPV vaccine ...
Tao Haskins-Coulter +3 more
doaj +2 more sources
Cellular immunogenicity of human papillomavirus vaccines Cervarix and Gardasil in adults with HIV infection [PDF]
Human papillomavirus (HPV) infection is a frequent cause of malignant and non-malignant disease, in particular among persons with HIV. HPV serotype-specific anti L1 antibodies protect against HPV infection but little is known about prophylactic HPV ...
Maria Zurek Munk-Madsen +7 more
doaj +2 more sources
Prophylactic vaccines against HPV-caused cervical cancer: novel vaccines are still demanded [PDF]
Several high-risk types of human papillomaviruses (HPVs) are associated with cervical cancer and other malignancies. Despite the tremendous success of marketed prophylactic HPV vaccines for the past 18 years, cervical cancer remains a significant global ...
Sogand Amiri +7 more
doaj +2 more sources
Prevalence, Characteristics, and Distribution of Human Papillomavirus According to Age and HIV Status in Women of Eastern Cape Province, South Africa [PDF]
Human papillomavirus (HPV) is a sexually transmitted infection associated with the development of cervical cancer. This study investigated cervical HPV prevalence, characteristics, and distribution according to age and human immunodeficiency virus (HIV ...
Zizipho Z. A. Mbulawa +4 more
doaj +2 more sources
Mozambique has one of the highest rates of cervical cancer in the world. Human papillomavirus (HPV) vaccination was introduced in 2021. This study evaluated the health and economic impact of the current HPV vaccine (GARDASIL® hereafter referred to as ...
Esperança Lourenço Guimarães +13 more
doaj +1 more source
Human papillomavirus (HPV) prevalence and genotype distribution data is important for HPV vaccine monitoring. This study investigated the prevalence and distribution of HPV genotypes in cervical lesions of unvaccinated women referred to Nelson Mandela ...
Zizipho Z A Mbulawa +4 more
doaj +2 more sources
Capsomer vaccines protect mice from vaginal challenge with human papillomavirus. [PDF]
Capsomers were produced in bacteria as glutathione-S-transferase (GST) fusion proteins with human papillomavirus type 16 L1 lacking the first nine and final 29 residues (GST-HPV16L1Δ) alone or linked with residues 13-47 of HPV18, HPV31 and HPV45 L2 in ...
Wai-Hong Wu +7 more
doaj +1 more source
Cross-neutralizing antibodies elicited by the Cervarix® human papillomavirus vaccine display a range of Alpha-9 inter-type specificities. [PDF]
The highly efficacious human papillomavirus (HPV) vaccines contain virus-like particles (VLP) representing genotypes HPV16 and HPV18, which together account for approximately 70% of cervical cancer cases. Vaccine-type protection is thought to be mediated
Bissett SL +4 more
europepmc +2 more sources
Adjuvants in vaccines registered for human use [PDF]
Vaccination is one of the most efficient strategies for prevention of infection diseases, but with introduction of sub-unit vaccines with lower immunogenicity adjuvants were needed to enhance the immune response.
Filipić Brankica +1 more
doaj +1 more source
ContextIt has been more than 10 years since the human papillomavirus (HPV) vaccination program was initiated in most advanced countries. Thus, it seems necessary to change the uterine cervical cancer screening strategy.
Javier Freire-Salinas +8 more
doaj +1 more source

