Results 41 to 50 of about 79,790 (226)

Dicritical nilpotent holomorphic foliations

open access: yes, 2017
We study in this paper several properties concerning singularities of foliations in $(\mathbb{C}^3,\mathbf{0})$ that are pull-back of dicritical foliations in $(\mathbb{C}^2,\mathbf{0})$. Particularly, we will investigate the existence of first integrals
Fernández, Jorge Mozo   +2 more
core   +1 more source

Transforming Brain Health With Neurotechnology Convergence (Part II): Intelligent Neurointervention Systems for Neurological Disorders

open access: yesBrain Health, EarlyView.
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye   +14 more
wiley   +1 more source

Raconte-moi une histoire : La rencontre entre mythologie égyptienne et les neurosciences de l'éducation au service des jeunes placés en institution

open access: yesCortica, 2023
L’objectif central de ce travail est d’oser la multidisciplinarité entre sciences sociales et neuroscience afin de mieux cibler l’intervention auprès des jeunes ayant vécus des traumatismes.
Olivier Mottier
doaj   +1 more source

Weaning from ketogenic diet therapy in children with epilepsy: Insights from a retrospective study

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to describe weaning practices following ketogenic diet therapy (KDT) in children with epilepsy and to identify clinical factors associated with seizure exacerbation or antiseizure medication adjustments during or after weaning from KDT.
Noémie Donnard   +10 more
wiley   +1 more source

Les « plis de la mémoire » chez Descartes et ses contemporains : médecine et métaphysique

open access: yesCahiers François Viète
This article discusses the issue of memory traces, and more specifically the notion of « fold of memory » in René Descartes and some of his contemporaries and successors.
Juliette Morice
doaj   +1 more source

Exploring pathways leading to drug‐resistant epilepsy for patients with cryptogenic new onset refractory status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective Cryptogenic new onset refractory status epilepticus (cNORSE) carries high risks of long‐term disability and post‐NORSE epilepsy, but mechanisms remain unclear. We aimed to assess the predictive value of inflammatory and brain injury biomarkers and determine whether immune disturbances persist in the chronic phase. Methods We enrolled
Aurélie Hanin   +34 more
wiley   +1 more source

Effet-dose de l’acide oléique alimentaire. Cet acide est-il conditionnellement essentiel ?

open access: yesOléagineux, Corps gras, Lipides, 2000
Dans un travail précédent [1] nous avons montré que, globalement, au terme de la période de gestation-lactation chez des rats de 21 jours, la carence alimentaire en acide oléique entraîne une diminution de la concentration en 18:1(n-9); la synthèse ...
Bourre Jean-Marie   +2 more
doaj   +1 more source

Evolution of the European Medicines Agency clinical guidelines for epilepsy drug development between 2010 and 2025: A comparative analysis by the ILAE Task Force on Regulatory Affairs

open access: yesEpilepsia, EarlyView.
Abstract Objective The latest European Medicines Agency (EMA) guideline on the clinical investigation of medicines to treat epileptic disorders was adopted by the EMA Committee for Medicinal Products for Human Use in 2025. We compared this guideline with the previous version (2010), highlighting areas where significant revisions were introduced ...
Stéphane Auvin   +7 more
wiley   +1 more source

A phase 3, randomized clinical trial of soticlestat as adjunctive therapy for Lennox–Gastaut syndrome

open access: yesEpilepsia, EarlyView.
Soticlestat as adjunctive therapy for Lennox–Gastaut syndrome. Abstract Objective There remains a need for new treatments for Lennox–Gastaut syndrome (LGS), a developmental and epileptic encephalopathy with a heterogenous patient population that often requires polytherapy. The phase 3, randomized SKYWAY study (NCT04938427) investigated the efficacy and
Renzo Guerrini   +15 more
wiley   +1 more source

On the Singular Scheme of Split Foliations

open access: yes, 2014
We prove that the tangent sheaf of a codimension one locally free distribution splits as a sum of line bundles if and only if its singular scheme is arithmetically Cohen-Macaulay.
Corrêa Jr, Maurício   +2 more
core   +1 more source

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