Results 111 to 120 of about 42,575 (291)

MUC1 as a Survival Effector of Radiotherapy‐Induced Epithelial Hybrid States in Basal‐Like Breast Cancer

International Journal of Cancer, EarlyView.
Basal‐like breast cancer (BLBC) is aggressive and often exhibits inherent or acquired resistance to radiotherapy (RT), a primary treatment option. RT resistance is underpinned by molecular alterations, many of which are poorly understood. Here, RT‐induced transcriptomic changes were analyzed using bulk and spatial sequencing in a BLBC mouse model and ...
Garyfallia Pantelaiou‐Prokaki, Husam Bamahmoud, Nadine S. Georges, Shaishavi Jansari, Annika Jung, Daniela Grimm, Evangelos Prokakis, Fabian Alexander Gayer, Maryam Deldar, Christian Dullin, Julia Gallwas, Florian Wegwitz, Frauke Alves   +12 more
wiley   +1 more source

Case Report of Spinal Cord Trauma with Incidental Finding of Rare Cervical Spine Malformation: Bipartite Atlas

Antecedentes: Las anomalías congénitas del atlas son hallazgos raros y a menudo asintomáticos, detectados accidentalmente en pacientes traumatizados y más raramente, en pacientes no traumatizados.
Buenrostro Torres, Luis Manuel, Ruiz Flores, Milton Inocencio, Mizrahi Aguado, Abraham, Morales Valencia, Carlos, Morales Valencia , Carlos, Reyna Martinez , Eduardo, Rodriguez Vega, Kevin Biblain   +6 more
core   +1 more source

Anterior cervical vertebrae of the theropod Aerosteon riocoloradensis.

, 2013
Atlas and cervical 3 centrum (MCNA-PV-3137; cast) in left lateral view. (A)-Atlas. (B)-Cervical 3 centrum. Scale bars equal 5 cm. Abbreviations: ic, intercentrum; na, neural arch; pa, parapophysis; pl, pleurocoel; pnec, pneumatocoel.
Oscar A. Alcober (197700), Ricardo N. Martinez (197696), Jeffrey A. Wilson (36584), Paul C. Sereno (36583), Hans C. E. Larsson (210480), David J. Varricchio (132149)   +5 more
core   +1 more source

Deep learning‐based prediction of cervical lymph node metastasis and genetic alterations from whole‐slide images of thyroid cancer frozen sections

Interdisciplinary Medicine, EarlyView.
Deep learning models accurately predict cervical lymph node metastasis and key genetic mutations (BRAF/TERT) directly from thyroid cancer frozen sections. This AI‐driven pipeline provides a rapid real‐time tool to guide intraoperative surgical decisions, helping to optimize surgical extent and prevent both over‐ and under‐treatment without the need for
Mingxing Qiu, Jinbang Li, Shujing Guo, Danyi Li, Chengyu Lu, Chenglong Zhao, Jiankun He, Hanxi Wang, Qiao Bai, Aihetaimu Aimaier, Zhijian Cen, Rui Mao, Zimo Ye, Jiaxue Zang, Zhining Zhuo, Lijuan Qu, Yueping Liu, Jing Cui, Xiaohong Yao, Xiuwu Bian, Li Liang   +20 more
wiley   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Cerebral Blood Transit in Sickle Cell Anemia

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Sickle cell anemia (SCA) patients upregulate cerebral blood flow to compensate for decreased arterial oxygen content. Such hyperemic conditions can manifest as venous hyperintense signal on arterial spin labeling (ASL) MRI, which may reflect faster capillary blood transit, altered oxygen extraction fraction (OEF), and infarct risk ...
Wesley T. Richerson, Megan A. Aumann, Alexander K. Song, Samantha Davis, Lauren Milner, Maria Garza, Dann Martin, L. Taylor Davis, Sumit Pruthi, Lori C. Jordan, Manus J. Donahue   +10 more
wiley   +1 more source

Comparison of Kinesiology Taping and Instrument Assisted Soft Tissue Mobilization in Cervicogenic Headache: A Randomized Clinical Trial

Journal Riphah College of Rehabilitation Sciences
: Background: Cervicogenic headache is a common condition caused by issue in the cervical spine, leading to chronic head pain. Various treatments exist, including kinesiology Taping and Instrument Assisted Soft Tissue Mobilization, but there is limited
Sana Javaid, Zainab Noor Qazi, Muhammad Ansar, Mahnoor Zia   +3 more
doaj  

Shared foraging behaviors between hyenas and hominins in the Middle Paleolithic Levant: New evidence from Geula Cave, Israel

Journal of Quaternary Science, EarlyView.
ABSTRACT While competition with large carnivores is likely to have shaped Middle Paleolithic hominins' subsistence behavior, palimpsested human and carnivore accumulations render the signal challenging to isolate. This study presents a detailed zooarchaeological and taphonomic analysis of a non‐anthropogenic faunal assemblage from a MIS 5 (~130–80 ka ...
Meir Orbach, Omry Barzilai, Israel Hershkovitz, Ma'ayan Lev, Reuven Yeshurun   +4 more
wiley   +1 more source

Servikal disk hernisi tanılı hastalarda spinal dekompresyon tedavisi ile yüksek yoğunluklu lazer terapinin etkinliğinin araştırılması = Investigation of the efficacy of spinal local decompression therapy and high intensity laser therapy in patients with cervical disc herniation

, 2023
Servikal disk hernisi, disk dejenarasyonu ile aynı zamanda kemik ve eklemlerdeki doğal yapının bozulmasıyla beraber ortaya çıkmaktadır. Bu çalışmanın amacı, servikal disk hernisi tanılı hastalarda tedavisinde kullanılan Spinal Lokal Dekompresyon Tedavisi
Jabbarlı, Rufat
core  

WDR72 Drives Esophageal Squamous Cell Carcinoma Progression by Inhibiting Autophagy via the PI3K/Akt/mTOR Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with a high rate of recurrence and metastasis, necessitating the identification of novel therapeutic targets. WD repeat‐containing protein 72 (WDR72) has been linked to various cancers, but its specific biological function and underlying mechanism in ESCC remain largely ...
Hao Wu, Zhong‐Xiang Jiang, Zheng Jiang
wiley   +1 more source